ADAPTIVE IMMUNE RESPONSE |
GO_-_Biological_Process.gmt.txt |
-3.2 |
0.04011 |
8.0 |
3.0 |
0.47 |
APC/C-mediated degradation of cell cycle proteins |
Pathways_-_Reactome.gmt.txt |
-3.0 |
0.01417 |
53.0 |
9.0 |
3.14 |
APC/C:Cdc20 mediated degradation of Securin |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.00951 |
39.0 |
8.0 |
2.31 |
APC/C:Cdc20 mediated degradation of mitotic proteins |
Pathways_-_Reactome.gmt.txt |
-3.1 |
0.01332 |
43.0 |
8.0 |
2.55 |
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
Pathways_-_Reactome.gmt.txt |
-3.1 |
0.01332 |
43.0 |
8.0 |
2.55 |
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
Pathways_-_Reactome.gmt.txt |
-3.0 |
0.01417 |
44.0 |
8.0 |
2.6 |
Activation of ATR in response to replication stress |
Pathways_-_Reactome.gmt.txt |
-2.4 |
0.035 |
27.0 |
5.0 |
1.6 |
Activation of NF-kappaB in B Cells |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.01001 |
48.0 |
9.0 |
2.84 |
Antigen processing-Cross presentation |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.01001 |
48.0 |
9.0 |
2.84 |
Apoptosis |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.01001 |
85.0 |
13.0 |
5.03 |
Assembly of the ORC complex at the origin of replication |
Pathways_-_Reactome.gmt.txt |
-3.8 |
0.00673 |
6.0 |
3.0 |
0.36 |
Assembly of the pre-replicative complex |
Pathways_-_Reactome.gmt.txt |
-4.9 |
0.00318 |
47.0 |
11.0 |
2.78 |
Association of licensing factors with the pre-replicative complex |
Pathways_-_Reactome.gmt.txt |
-3.9 |
0.00626 |
10.0 |
4.0 |
0.59 |
Autodegradation of Cdh1 by Cdh1:APC/C |
Pathways_-_Reactome.gmt.txt |
-3.5 |
0.00925 |
38.0 |
8.0 |
2.25 |
Autodegradation of the E3 ubiquitin ligase COP1 |
Pathways_-_Reactome.gmt.txt |
-3.8 |
0.00642 |
35.0 |
8.0 |
2.07 |
BIOCARTA ACTINY PATHWAY |
Pathways_-_KEGGBioCarta.gmt.txt |
-3.2 |
0.02389 |
13.0 |
4.0 |
0.77 |
BIOCARTA ATM PATHWAY |
Pathways_-_KEGGBioCarta.gmt.txt |
-2.5 |
0.0406 |
11.0 |
3.0 |
0.65 |
BIOCARTA P53HYPOXIA PATHWAY |
Pathways_-_KEGGBioCarta.gmt.txt |
-2.5 |
0.0406 |
11.0 |
3.0 |
0.65 |
BIOCARTA SALMONELLA PATHWAY |
Pathways_-_KEGGBioCarta.gmt.txt |
-2.9 |
0.02854 |
9.0 |
3.0 |
0.53 |
CDC6 association with the ORC:origin complex |
Pathways_-_Reactome.gmt.txt |
-2.9 |
0.01759 |
9.0 |
3.0 |
0.53 |
CDK-mediated phosphorylation and removal of Cdc6 |
Pathways_-_Reactome.gmt.txt |
-3.9 |
0.00574 |
34.0 |
8.0 |
2.01 |
CDT1 association with the CDC6:ORC:origin complex |
Pathways_-_Reactome.gmt.txt |
-5.7 |
7.5E-4 |
40.0 |
11.0 |
2.37 |
Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
Pathways_-_Reactome.gmt.txt |
-3.1 |
0.01332 |
43.0 |
8.0 |
2.55 |
Cell Cycle |
Pathways_-_Reactome.gmt.txt |
-2.8 |
0.01955 |
260.0 |
27.0 |
15.39 |
Cell Cycle Checkpoints |
Pathways_-_Reactome.gmt.txt |
-3.7 |
0.0073 |
79.0 |
13.0 |
4.68 |
Cross-presentation of soluble exogenous antigens (endosomes) |
Pathways_-_Reactome.gmt.txt |
-3.5 |
0.00951 |
31.0 |
7.0 |
1.83 |
Cyclin A:Cdk2-associated events at S phase entry |
Pathways_-_Reactome.gmt.txt |
-3.6 |
0.00848 |
45.0 |
9.0 |
2.66 |
Cyclin E associated events during G1/S transition |
Pathways_-_Reactome.gmt.txt |
-3.6 |
0.00848 |
45.0 |
9.0 |
2.66 |
DNA Replication |
Pathways_-_Reactome.gmt.txt |
-3.7 |
0.00753 |
140.0 |
19.0 |
8.29 |
DNA Replication Pre-Initiation |
Pathways_-_Reactome.gmt.txt |
-4.0 |
0.00574 |
57.0 |
11.0 |
3.37 |
Degradation of beta-catenin by the destruction complex |
Pathways_-_Reactome.gmt.txt |
-3.5 |
0.00951 |
47.0 |
9.0 |
2.78 |
Destabilization of mRNA by AUF1 (hnRNP D0) |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.00951 |
39.0 |
8.0 |
2.31 |
Downstream Signaling Events Of B Cell Receptor (BCR) |
Pathways_-_Reactome.gmt.txt |
-2.6 |
0.02687 |
70.0 |
10.0 |
4.14 |
E2F-enabled inhibition of pre-replication complex formation |
Pathways_-_Reactome.gmt.txt |
-2.7 |
0.02225 |
10.0 |
3.0 |
0.59 |
ENDONUCLEASE ACTIVITY |
GO_-_Molecular_Function.gmt.txt |
-2.7 |
0.04505 |
10.0 |
3.0 |
0.59 |
ER-Phagosome pathway |
Pathways_-_Reactome.gmt.txt |
-3.7 |
0.0073 |
44.0 |
9.0 |
2.6 |
G1/S DNA Damage Checkpoints |
Pathways_-_Reactome.gmt.txt |
-3.8 |
0.00666 |
43.0 |
9.0 |
2.55 |
G1/S Transition |
Pathways_-_Reactome.gmt.txt |
-3.2 |
0.01267 |
79.0 |
12.0 |
4.68 |
GCATTTG,MIR-105 |
TFmiRNA_Targets.gmt.txt |
-3.4 |
0.04965 |
65.0 |
11.0 |
3.85 |
GTAGGCA,MIR-189 |
TFmiRNA_Targets.gmt.txt |
-4.3 |
0.01708 |
13.0 |
5.0 |
0.77 |
GTTGNYNNRGNAAC UNKNOWN |
TFmiRNA_Targets.gmt.txt |
-3.7 |
0.03976 |
29.0 |
7.0 |
1.72 |
Generic Transcription Pathway |
Pathways_-_Reactome.gmt.txt |
-3.2 |
0.01135 |
108.0 |
15.0 |
6.39 |
HIV HIV Infection |
HIV_Collection.gmt.txt |
-2.6 |
0.03465 |
135.0 |
16.0 |
7.99 |
HIV Host Interactions of HIV factors |
HIV_Collection.gmt.txt |
-3.1 |
0.0246 |
90.0 |
13.0 |
5.33 |
HIV Vif-mediated degradation of APOBEC3G |
HIV_Collection.gmt.txt |
-3.7 |
0.01349 |
36.0 |
8.0 |
2.13 |
HIV Vpu mediated degradation of CD4 |
HIV_Collection.gmt.txt |
-3.7 |
0.01349 |
36.0 |
8.0 |
2.13 |
KEGG PROTEASOME |
Pathways_-_KEGGBioCarta.gmt.txt |
-2.9 |
0.02854 |
29.0 |
6.0 |
1.72 |
M/G1 Transition |
Pathways_-_Reactome.gmt.txt |
-4.0 |
0.00574 |
57.0 |
11.0 |
3.37 |
Metabolism of amino acids and derivatives |
Pathways_-_Reactome.gmt.txt |
-2.4 |
0.035 |
85.0 |
11.0 |
5.03 |
Mitotic G1-G1/S phases |
Pathways_-_Reactome.gmt.txt |
-2.9 |
0.01863 |
95.0 |
13.0 |
5.62 |
Mitotic M-M/G1 phases |
Pathways_-_Reactome.gmt.txt |
-3.5 |
0.00951 |
123.0 |
17.0 |
7.28 |
NEGATIVE REGULATION OF SIGNAL TRANSDUCTION |
GO_-_Biological_Process.gmt.txt |
-2.9 |
0.04823 |
15.0 |
4.0 |
0.89 |
Orc1 removal from chromatin |
Pathways_-_Reactome.gmt.txt |
-4.7 |
0.00318 |
49.0 |
11.0 |
2.9 |
PROTEASOME COMPLEX |
GO_-_Cellular_Component.gmt.txt |
-2.7 |
0.03333 |
16.0 |
4.0 |
0.95 |
Pre-NOTCH Transcription and Translation |
Pathways_-_Reactome.gmt.txt |
-2.5 |
0.02905 |
11.0 |
3.0 |
0.65 |
RESPONSE TO RADIATION |
GO_-_Biological_Process.gmt.txt |
-3.3 |
0.03473 |
25.0 |
6.0 |
1.48 |
Regulation of APC/C activators between G1/S and early anaphase |
Pathways_-_Reactome.gmt.txt |
-2.7 |
0.02318 |
49.0 |
8.0 |
2.9 |
Regulation of Apoptosis |
Pathways_-_Reactome.gmt.txt |
-4.4 |
0.00382 |
37.0 |
9.0 |
2.19 |
Regulation of DNA replication |
Pathways_-_Reactome.gmt.txt |
-4.5 |
0.00318 |
51.0 |
11.0 |
3.02 |
Regulation of activated PAK-2p34 by proteasome mediated degradation |
Pathways_-_Reactome.gmt.txt |
-3.9 |
0.00574 |
34.0 |
8.0 |
2.01 |
Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
Pathways_-_Reactome.gmt.txt |
-2.5 |
0.03156 |
62.0 |
9.0 |
3.67 |
Regulation of mitotic cell cycle |
Pathways_-_Reactome.gmt.txt |
-3.0 |
0.01417 |
53.0 |
9.0 |
3.14 |
Regulation of ornithine decarboxylase (ODC) |
Pathways_-_Reactome.gmt.txt |
-4.1 |
0.00574 |
33.0 |
8.0 |
1.95 |
Removal of licensing factors from origins |
Pathways_-_Reactome.gmt.txt |
-4.7 |
0.00318 |
49.0 |
11.0 |
2.9 |
S Phase |
Pathways_-_Reactome.gmt.txt |
-4.2 |
0.00492 |
81.0 |
14.0 |
4.79 |
SCF(Skp2)-mediated degradation of p27/p21 |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.01001 |
40.0 |
8.0 |
2.37 |
SCF-beta-TrCP mediated degradation of Emi1 |
Pathways_-_Reactome.gmt.txt |
-3.7 |
0.00727 |
36.0 |
8.0 |
2.13 |
Signaling by Wnt |
Pathways_-_Reactome.gmt.txt |
-3.5 |
0.00951 |
47.0 |
9.0 |
2.78 |
Sphingolipid metabolism |
Pathways_-_Reactome.gmt.txt |
-2.3 |
0.04035 |
20.0 |
4.0 |
1.18 |
Stabilization of p53 |
Pathways_-_Reactome.gmt.txt |
-3.7 |
0.00727 |
36.0 |
8.0 |
2.13 |
Switching of origins to a post-replicative state |
Pathways_-_Reactome.gmt.txt |
-4.7 |
0.00318 |
49.0 |
11.0 |
2.9 |
Synthesis of DNA |
Pathways_-_Reactome.gmt.txt |
-4.2 |
0.00463 |
71.0 |
13.0 |
4.2 |
TRANSCRIPTION ELONGATION REGULATOR ACTIVITY |
GO_-_Molecular_Function.gmt.txt |
-3.2 |
0.03238 |
8.0 |
3.0 |
0.47 |
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A |
Pathways_-_Reactome.gmt.txt |
-4.5 |
0.00318 |
36.0 |
9.0 |
2.13 |
Ubiquitin-dependent degradation of Cyclin D |
Pathways_-_Reactome.gmt.txt |
-3.9 |
0.00574 |
34.0 |
8.0 |
2.01 |
Ubiquitin-dependent degradation of Cyclin D1 |
Pathways_-_Reactome.gmt.txt |
-3.9 |
0.00574 |
34.0 |
8.0 |
2.01 |
chr10p15 |
Chromosomal_Bands.gmt.txt |
-2.9 |
0.01782 |
15.0 |
4.0 |
0.89 |
chr12p12 |
Chromosomal_Bands.gmt.txt |
-2.4 |
0.028 |
19.0 |
4.0 |
1.12 |
chr12q15 |
Chromosomal_Bands.gmt.txt |
-4.1 |
0.00333 |
9.0 |
4.0 |
0.53 |
chr13q34 |
Chromosomal_Bands.gmt.txt |
-2.7 |
0.0213 |
10.0 |
3.0 |
0.59 |
chr1p13 |
Chromosomal_Bands.gmt.txt |
-2.5 |
0.02637 |
34.0 |
6.0 |
2.01 |
chr1p21 |
Chromosomal_Bands.gmt.txt |
-2.4 |
0.028 |
12.0 |
3.0 |
0.71 |
chr2p22 |
Chromosomal_Bands.gmt.txt |
-2.5 |
0.02637 |
18.0 |
4.0 |
1.07 |
chr2q12 |
Chromosomal_Bands.gmt.txt |
-2.2 |
0.03259 |
13.0 |
3.0 |
0.77 |
chr3q22 |
Chromosomal_Bands.gmt.txt |
-2.5 |
0.02595 |
11.0 |
3.0 |
0.65 |
chr5q11 |
Chromosomal_Bands.gmt.txt |
-3.4 |
0.0089 |
12.0 |
4.0 |
0.71 |
chr5q12 |
Chromosomal_Bands.gmt.txt |
-5.7 |
2.1E-4 |
17.0 |
7.0 |
1.01 |
chr8p22 |
Chromosomal_Bands.gmt.txt |
-2.4 |
0.028 |
12.0 |
3.0 |
0.71 |
chr8q21 |
Chromosomal_Bands.gmt.txt |
-2.7 |
0.0208 |
16.0 |
4.0 |
0.95 |
chr9q21 |
Chromosomal_Bands.gmt.txt |
-2.1 |
0.04 |
14.0 |
3.0 |
0.83 |
chr9q31 |
Chromosomal_Bands.gmt.txt |
-2.4 |
0.028 |
12.0 |
3.0 |
0.71 |
chrxq24 |
Chromosomal_Bands.gmt.txt |
-2.2 |
0.03259 |
13.0 |
3.0 |
0.77 |
chrxq26 |
Chromosomal_Bands.gmt.txt |
-2.4 |
0.028 |
12.0 |
3.0 |
0.71 |
p53-Dependent G1 DNA Damage Response |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.01001 |
40.0 |
8.0 |
2.37 |
p53-Dependent G1/S DNA damage checkpoint |
Pathways_-_Reactome.gmt.txt |
-3.4 |
0.01001 |
40.0 |
8.0 |
2.37 |
p53-Independent DNA Damage Response |
Pathways_-_Reactome.gmt.txt |
-4.5 |
0.00318 |
36.0 |
9.0 |
2.13 |
p53-Independent G1/S DNA damage checkpoint |
Pathways_-_Reactome.gmt.txt |
-4.5 |
0.00318 |
36.0 |
9.0 |
2.13 |