PEACHi
GeneSet HIV HIV Infection (HIV_Collection.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.6 0.03465 135.0 30.0 18.65
o-o -2.4 0.04111 135.0 20.0 11.32
o+o -2.6 0.03465 135.0 16.0 7.99
DownRegulated -2.4 0.0286 135.0 94.0 79.72
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000094914 AAAS o--a
ENSG00000100280 AP1B1 o--b
ENSG00000166747 AP1G1 o+-
ENSG00000072958 AP1M1 o--b
ENSG00000106367 AP1S1 ---
ENSG00000182287 AP1S2 -+o
ENSG00000196961 AP2A1 ---
ENSG00000006125 AP2B1 ---
ENSG00000161203 AP2M1 ---
ENSG00000042753 AP2S1 o--b
ENSG00000143761 ARF1 o--b
ENSG00000047249 ATP6V1H o+o
ENSG00000166710 B2M o+o
ENSG00000175334 BANF1 o--b
ENSG00000166167 BTRC --o
ENSG00000134480 CCNH -o-
ENSG00000082258 CCNT2 o-o
ENSG00000198821 CD247 NonAssociatedWithProgression
ENSG00000178562 CD28 o+o
ENSG00000010610 CD4 o--b
ENSG00000134058 CDK7 o+o
ENSG00000188986 COBRA1 o--b
ENSG00000060069 CTDP1 ---
ENSG00000166266 CUL5 o--b
ENSG00000121966 CXCR4 o--b
ENSG00000134516 DOCK2 o--a
ENSG00000105656 ELL o--a
ENSG00000155849 ELMO1 o+o
ENSG00000104884 ERCC2 ---
ENSG00000163161 ERCC3 o-o
ENSG00000168496 FEN1 NonAssociatedWithProgression
ENSG00000010810 FYN +oo
ENSG00000140307 GTF2A2 NonAssociatedWithProgression
ENSG00000137947 GTF2B NonAssociatedWithProgression
ENSG00000153767 GTF2E1 o++b
ENSG00000197265 GTF2E2 NonAssociatedWithProgression
ENSG00000125651 GTF2F1 o--a
ENSG00000188342 GTF2F2 NonAssociatedWithProgression
ENSG00000110768 GTF2H1 o++b
ENSG00000145736 GTF2H2 o++b
ENSG00000111358 GTF2H3 NonAssociatedWithProgression
ENSG00000206503 HLA-A +-o
ENSG00000137309 HMGA1 o--b
ENSG00000114030 KPNA1 NonAssociatedWithProgression
ENSG00000108424 KPNB1 o--a
ENSG00000182866 LCK o-o
ENSG00000105486 LIG1 o--a
ENSG00000174405 LIG4 -+o
ENSG00000136937 NCBP1 o+-
ENSG00000114503 NCBP2 o--b
ENSG00000136448 NMT1 o--b
ENSG00000152465 NMT2 NonAssociatedWithProgression
ENSG00000181163 NPM1 o--b
ENSG00000111581 NUP107 -+o
ENSG00000069248 NUP133 o+-
ENSG00000124789 NUP153 o+-
ENSG00000113569 NUP155 NonAssociatedWithProgression
ENSG00000030066 NUP160 NonAssociatedWithProgression
ENSG00000095319 NUP188 ---
ENSG00000155561 NUP205 -o-
ENSG00000132182 NUP210 o-o
ENSG00000126883 NUP214 NonAssociatedWithProgression
ENSG00000163002 NUP35 oo-
ENSG00000075188 NUP37 NonAssociatedWithProgression
ENSG00000093000 NUP50 NonAssociatedWithProgression
ENSG00000138750 NUP54 o-o
ENSG00000213024 NUP62 o--a
ENSG00000125450 NUP85 o--b
ENSG00000108559 NUP88 NonAssociatedWithProgression
ENSG00000102900 NUP93 o-o
ENSG00000110713 NUP98 o--a
ENSG00000139496 NUPL1 +-o
ENSG00000136243 NUPL2 o+-
ENSG00000175115 PACS1 ---
ENSG00000180370 PAK2 ---
ENSG00000181222 POLR2A ---
ENSG00000047315 POLR2B +oo
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000144231 POLR2D o--b
ENSG00000100142 POLR2F NonAssociatedWithProgression
ENSG00000168002 POLR2G NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000105258 POLR2I --o
ENSG00000005075 POLR2J ---
ENSG00000177700 POLR2L o-o
ENSG00000196313 POM121 o--b
ENSG00000196262 PPIA NonAssociatedWithProgression
ENSG00000164985 PSIP1 o-o
ENSG00000129084 PSMA1 o--a
ENSG00000106588 PSMA2 o+o
ENSG00000100567 PSMA3 o+o
ENSG00000041357 PSMA4 -+o
ENSG00000143106 PSMA5 o--a
ENSG00000100902 PSMA6 NonAssociatedWithProgression
ENSG00000101182 PSMA7 -+o
ENSG00000008018 PSMB1 o-o
ENSG00000126067 PSMB2 oo-
ENSG00000108294 PSMB3 -+o
ENSG00000159377 PSMB4 NonAssociatedWithProgression
ENSG00000100804 PSMB5 o--b
ENSG00000142507 PSMB6 o-o
ENSG00000136930 PSMB7 NonAssociatedWithProgression
ENSG00000204264 PSMB8 o--b
ENSG00000240065 PSMB9 o-o
ENSG00000100764 PSMC1 NonAssociatedWithProgression
ENSG00000161057 PSMC2 o+o
ENSG00000165916 PSMC3 o-o
ENSG00000013275 PSMC4 NonAssociatedWithProgression
ENSG00000087191 PSMC5 -+o
ENSG00000100519 PSMC6 o+o
ENSG00000173692 PSMD1 NonAssociatedWithProgression
ENSG00000101843 PSMD10 o+o
ENSG00000108671 PSMD11 NonAssociatedWithProgression
ENSG00000197170 PSMD12 oo-
ENSG00000185627 PSMD13 o--b
ENSG00000115233 PSMD14 o+o
ENSG00000175166 PSMD2 ---
ENSG00000108344 PSMD3 ---
ENSG00000159352 PSMD4 NonAssociatedWithProgression
ENSG00000095261 PSMD5 o++b
ENSG00000163636 PSMD6 o+o
ENSG00000099341 PSMD8 o--b
ENSG00000110801 PSMD9 o--b
ENSG00000100911 PSME2 NonAssociatedWithProgression
ENSG00000131467 PSME3 o-o
ENSG00000068878 PSME4 o--b
ENSG00000125818 PSMF1 o-+
ENSG00000136238 RAC1 NonAssociatedWithProgression
ENSG00000101146 RAE1 -o-
ENSG00000132341 RAN o--b
ENSG00000099901 RANBP1 NonAssociatedWithProgression
ENSG00000153201 RANBP2 o+o
ENSG00000100401 RANGAP1 o-o
ENSG00000100387 RBX1 o--a
ENSG00000180198 RCC1 o--a
ENSG00000204356 RDBP o-o
ENSG00000111880 RNGTT NonAssociatedWithProgression
ENSG00000101654 RNMT NonAssociatedWithProgression
ENSG00000143947 RPS27A o+o
ENSG00000085415 SEH1L o-o
ENSG00000113558 SKP1 ---
ENSG00000151729 SLC25A4 -oo
ENSG00000005022 SLC25A5 NonAssociatedWithProgression
ENSG00000169100 SLC25A6 o-o
ENSG00000149136 SSRP1 o--b
ENSG00000092201 SUPT16H o--a
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000147133 TAF1 NonAssociatedWithProgression
ENSG00000166337 TAF10 o--a
ENSG00000064995 TAF11 o--b
ENSG00000120656 TAF12 o--a
ENSG00000197780 TAF13 o+o
ENSG00000130699 TAF4 o++b
ENSG00000141384 TAF4B NonAssociatedWithProgression
ENSG00000148835 TAF5 o--a
ENSG00000106290 TAF6 NonAssociatedWithProgression
ENSG00000085231 TAF9 o+o
ENSG00000112592 TBP NonAssociatedWithProgression
ENSG00000187735 TCEA1 NonAssociatedWithProgression
ENSG00000154582 TCEB1 NonAssociatedWithProgression
ENSG00000103363 TCEB2 o--a
ENSG00000011007 TCEB3 NonAssociatedWithProgression
ENSG00000101158 TH1L o--b
ENSG00000047410 TPR o+-
ENSG00000074319 TSG101 NonAssociatedWithProgression
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---
ENSG00000160948 VPS28 o-o
ENSG00000155975 VPS37A +o+
ENSG00000139722 VPS37B o--b
ENSG00000185049 WHSC2 o--b
ENSG00000082898 XPO1 o-o
ENSG00000152422 XRCC4 o++a
ENSG00000079246 XRCC5 -o-
ENSG00000196419 XRCC6 o--b