PEACHi
GeneSet Regulation of mRNA Stability by Proteins that Bind AU-rich Elements (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.5 0.03236 62.0 16.0 8.57
oo- -2.2 0.04432 62.0 4.0 1.18
o+o -2.5 0.03156 62.0 9.0 3.67
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000140350 ANP32A o--a
ENSG00000162290 DCP1A o+o
ENSG00000172795 DCP2 o-o
ENSG00000083520 DIS3 o--a
ENSG00000114867 EIF4G1 ---
ENSG00000066044 ELAVL1 NonAssociatedWithProgression
ENSG00000171311 EXOSC1 NonAssociatedWithProgression
ENSG00000130713 EXOSC2 o--b
ENSG00000107371 EXOSC3 NonAssociatedWithProgression
ENSG00000178896 EXOSC4 --o
ENSG00000077348 EXOSC5 o--a
ENSG00000223496 EXOSC6 o--a
ENSG00000075914 EXOSC7 NonAssociatedWithProgression
ENSG00000123737 EXOSC9 o--b
ENSG00000138668 HNRNPD oo-
ENSG00000204389 HSPA1A o--b
ENSG00000109971 HSPA8 ---
ENSG00000106211 HSPB1 o--b
ENSG00000088247 KHSRP o--b
ENSG00000112062 MAPK14 o++b
ENSG00000162889 MAPKAPK2 o--a
ENSG00000126883 NUP214 NonAssociatedWithProgression
ENSG00000070756 PABPC1 o--b
ENSG00000140694 PARN o-o
ENSG00000154229 PRKCA oo+
ENSG00000163932 PRKCD NonAssociatedWithProgression
ENSG00000129084 PSMA1 o--a
ENSG00000106588 PSMA2 o+o
ENSG00000100567 PSMA3 o+o
ENSG00000041357 PSMA4 -+o
ENSG00000143106 PSMA5 o--a
ENSG00000100902 PSMA6 NonAssociatedWithProgression
ENSG00000101182 PSMA7 -+o
ENSG00000008018 PSMB1 o-o
ENSG00000126067 PSMB2 oo-
ENSG00000108294 PSMB3 -+o
ENSG00000159377 PSMB4 NonAssociatedWithProgression
ENSG00000100804 PSMB5 o--b
ENSG00000142507 PSMB6 o-o
ENSG00000136930 PSMB7 NonAssociatedWithProgression
ENSG00000204264 PSMB8 o--b
ENSG00000240065 PSMB9 o-o
ENSG00000100764 PSMC1 NonAssociatedWithProgression
ENSG00000161057 PSMC2 o+o
ENSG00000165916 PSMC3 o-o
ENSG00000013275 PSMC4 NonAssociatedWithProgression
ENSG00000087191 PSMC5 -+o
ENSG00000100519 PSMC6 o+o
ENSG00000173692 PSMD1 NonAssociatedWithProgression
ENSG00000101843 PSMD10 o+o
ENSG00000108671 PSMD11 NonAssociatedWithProgression
ENSG00000197170 PSMD12 oo-
ENSG00000185627 PSMD13 o--b
ENSG00000115233 PSMD14 o+o
ENSG00000175166 PSMD2 ---
ENSG00000108344 PSMD3 ---
ENSG00000159352 PSMD4 NonAssociatedWithProgression
ENSG00000095261 PSMD5 o++b
ENSG00000163636 PSMD6 o+o
ENSG00000099341 PSMD8 o--b
ENSG00000110801 PSMD9 o--b
ENSG00000100911 PSME2 NonAssociatedWithProgression
ENSG00000131467 PSME3 o-o
ENSG00000068878 PSME4 o--b
ENSG00000125818 PSMF1 o-+
ENSG00000143947 RPS27A o+o
ENSG00000119335 SET o--b
ENSG00000083312 TNPO1 oo-
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---
ENSG00000082898 XPO1 o-o
ENSG00000114127 XRN1 o++b
ENSG00000166913 YWHAB o--b
ENSG00000164924 YWHAZ o--b
ENSG00000128016 ZFP36 o--b
ENSG00000185650 ZFP36L1 o-o