PEACHi
GeneSet Apoptosis (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -3.0 0.01417 85.0 22.0 11.74
o+o -3.4 0.01001 85.0 13.0 5.03
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000100813 ACIN1 ---
ENSG00000087274 ADD1 +o+
ENSG00000142208 AKT1 ---
ENSG00000120868 APAF1 o++b
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000157500 APPL1 o+o
ENSG00000030110 BAK1 o--b
ENSG00000105327 BBC3 +oo
ENSG00000185825 BCAP31 ---
ENSG00000171791 BCL2 NonAssociatedWithProgression
ENSG00000171552 BCL2L1 ---
ENSG00000153094 BCL2L11 NonAssociatedWithProgression
ENSG00000015475 BID -oo
ENSG00000110330 BIRC2 NonAssociatedWithProgression
ENSG00000104081 BMF +-o
ENSG00000164305 CASP3 o++b
ENSG00000138794 CASP6 o++b
ENSG00000165806 CASP7 o-o
ENSG00000064012 CASP8 +-o
ENSG00000003402 CFLAR +-o
ENSG00000168036 CTNNB1 o--b
ENSG00000172115 CYCS o--b
ENSG00000196730 DAPK1 o++a
ENSG00000136279 DBNL o--a
ENSG00000160049 DFFA NonAssociatedWithProgression
ENSG00000184047 DIABLO o--a
ENSG00000087470 DNM1L NonAssociatedWithProgression
ENSG00000046604 DSG2 NonAssociatedWithProgression
ENSG00000096696 DSP NonAssociatedWithProgression
ENSG00000088986 DYNLL1 --o
ENSG00000121083 DYNLL2 NonAssociatedWithProgression
ENSG00000101412 E2F1 o--b
ENSG00000168040 FADD o--b
ENSG00000026103 FAS NonAssociatedWithProgression
ENSG00000168522 FNTA o-o
ENSG00000189060 H1F0 o--b
ENSG00000187837 HIST1H1C o--b
ENSG00000124575 HIST1H1D ---
ENSG00000189403 HMGB1 o--b
ENSG00000164104 HMGB2 o--b
ENSG00000114030 KPNA1 NonAssociatedWithProgression
ENSG00000108424 KPNB1 o--a
ENSG00000113368 LMNB1 o--b
ENSG00000179222 MAGED1 NonAssociatedWithProgression
ENSG00000107643 MAPK8 o+o
ENSG00000186868 MAPT o++a
ENSG00000136448 NMT1 o--b
ENSG00000180370 PAK2 ---
ENSG00000081277 PKP1 NonAssociatedWithProgression
ENSG00000178209 PLEC o--a
ENSG00000141682 PMAIP1 oo-
ENSG00000120910 PPP3CC NonAssociatedWithProgression
ENSG00000221823 PPP3R1 +oo
ENSG00000163932 PRKCD NonAssociatedWithProgression
ENSG00000065675 PRKCQ o+o
ENSG00000129084 PSMA1 o--a
ENSG00000106588 PSMA2 o+o
ENSG00000100567 PSMA3 o+o
ENSG00000041357 PSMA4 -+o
ENSG00000143106 PSMA5 o--a
ENSG00000100902 PSMA6 NonAssociatedWithProgression
ENSG00000101182 PSMA7 -+o
ENSG00000008018 PSMB1 o-o
ENSG00000126067 PSMB2 oo-
ENSG00000108294 PSMB3 -+o
ENSG00000159377 PSMB4 NonAssociatedWithProgression
ENSG00000100804 PSMB5 o--b
ENSG00000142507 PSMB6 o-o
ENSG00000136930 PSMB7 NonAssociatedWithProgression
ENSG00000204264 PSMB8 o--b
ENSG00000240065 PSMB9 o-o
ENSG00000100764 PSMC1 NonAssociatedWithProgression
ENSG00000161057 PSMC2 o+o
ENSG00000165916 PSMC3 o-o
ENSG00000013275 PSMC4 NonAssociatedWithProgression
ENSG00000087191 PSMC5 -+o
ENSG00000100519 PSMC6 o+o
ENSG00000173692 PSMD1 NonAssociatedWithProgression
ENSG00000101843 PSMD10 o+o
ENSG00000108671 PSMD11 NonAssociatedWithProgression
ENSG00000197170 PSMD12 oo-
ENSG00000185627 PSMD13 o--b
ENSG00000115233 PSMD14 o+o
ENSG00000175166 PSMD2 ---
ENSG00000108344 PSMD3 ---
ENSG00000159352 PSMD4 NonAssociatedWithProgression
ENSG00000095261 PSMD5 o++b
ENSG00000163636 PSMD6 o+o
ENSG00000099341 PSMD8 o--b
ENSG00000110801 PSMD9 o--b
ENSG00000100911 PSME2 NonAssociatedWithProgression
ENSG00000131467 PSME3 o-o
ENSG00000068878 PSME4 o--b
ENSG00000125818 PSMF1 o-+
ENSG00000137275 RIPK1 o--b
ENSG00000067900 ROCK1 o+o
ENSG00000143947 RPS27A o+o
ENSG00000182568 SATB1 o--a
ENSG00000197694 SPTAN1 NonAssociatedWithProgression
ENSG00000102572 STK24 o--b
ENSG00000198176 TFDP1 -o-
ENSG00000119139 TJP2 o++b
ENSG00000120889 TNFRSF10B o+o
ENSG00000067182 TNFRSF1A NonAssociatedWithProgression
ENSG00000141510 TP53 o--a
ENSG00000102871 TRADD NonAssociatedWithProgression
ENSG00000127191 TRAF2 o--b
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---
ENSG00000026025 VIM o--b
ENSG00000101966 XIAP o+-
ENSG00000166913 YWHAB o--b