GeneSet ADAPTIVE_IMMUNE_RESPONSE (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o+o -3.2 0.04011 8.0 3.0 0.47
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142867 BCL10 o+o
ENSG00000166278 C2 NonAssociatedWithProgression
ENSG00000137496 IL18BP o++a
ENSG00000113520 IL4 NonAssociatedWithProgression
ENSG00000172175 MALT1 +o+
ENSG00000135341 MAP3K7 NonAssociatedWithProgression
ENSG00000081237 PTPRC o+o
ENSG00000101082 SLA2 o+o
ENSG00000171150 SOCS5 oo-
ENSG00000105329 TGFB1 o--a
ENSG00000127191 TRAF2 o--b
ENSG00000175104 TRAF6 NonAssociatedWithProgression