PEACHi
GeneSet Generic Transcription Pathway (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o+o -3.2 0.01135 108.0 15.0 6.39
+o+ -3.4 0.01001 108.0 12.0 4.41
NonAssociatedWithProgression -3.3 0.00587 175.0 67.0 47.52
UpRegulated -4.2 0.00142 108.0 47.0 29.21
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000112237 CCNC o--a
ENSG00000132964 CDK8 o+o
ENSG00000177200 CHD9 o--a
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000173153 ESRRA ---
ENSG00000108773 KAT2A o--a
ENSG00000114166 KAT2B NonAssociatedWithProgression
ENSG00000161021 MAML1 o--b
ENSG00000013619 MAMLD1 oo+
ENSG00000125686 MED1 NonAssociatedWithProgression
ENSG00000133398 MED10 o+o
ENSG00000108510 MED13 NonAssociatedWithProgression
ENSG00000180182 MED14 -oo
ENSG00000099917 MED15 NonAssociatedWithProgression
ENSG00000175221 MED16 ---
ENSG00000124641 MED20 NonAssociatedWithProgression
ENSG00000112282 MED23 NonAssociatedWithProgression
ENSG00000008838 MED24 NonAssociatedWithProgression
ENSG00000104973 MED25 NonAssociatedWithProgression
ENSG00000105085 MED26 o--a
ENSG00000160563 MED27 o--a
ENSG00000164758 MED30 o+-
ENSG00000136146 MED4 NonAssociatedWithProgression
ENSG00000133997 MED6 NonAssociatedWithProgression
ENSG00000155868 MED7 NonAssociatedWithProgression
ENSG00000159479 MED8 o--b
ENSG00000084676 NCOA1 NonAssociatedWithProgression
ENSG00000140396 NCOA2 NonAssociatedWithProgression
ENSG00000124151 NCOA3 o+o
ENSG00000198646 NCOA6 o--b
ENSG00000148400 NOTCH1 o+o
ENSG00000134250 NOTCH2 o-o
ENSG00000074181 NOTCH3 o--b
ENSG00000174738 NR1D2 NonAssociatedWithProgression
ENSG00000131408 NR1H2 o--a
ENSG00000120798 NR2C1 NonAssociatedWithProgression
ENSG00000177463 NR2C2 NonAssociatedWithProgression
ENSG00000160113 NR2F6 NonAssociatedWithProgression
ENSG00000113580 NR3C1 o--a
ENSG00000115216 NRBP1 ---
ENSG00000186951 PPARA o++a
ENSG00000112033 PPARD ---
ENSG00000168214 RBPJ o--b
ENSG00000069667 RORA NonAssociatedWithProgression
ENSG00000198963 RORB NonAssociatedWithProgression
ENSG00000143365 RORC o--b
ENSG00000124813 RUNX2 +oo
ENSG00000186350 RXRA ---
ENSG00000204231 RXRB NonAssociatedWithProgression
ENSG00000082014 SMARCD3 +oo
ENSG00000100603 SNW1 NonAssociatedWithProgression
ENSG00000101849 TBL1X +-o
ENSG00000177565 TBL1XR1 o-o
ENSG00000187079 TEAD1 NonAssociatedWithProgression
ENSG00000137574 TGS1 NonAssociatedWithProgression
ENSG00000126351 THRA --o
ENSG00000130726 TRIM28 o--a
ENSG00000018408 WWTR1 NonAssociatedWithProgression
ENSG00000184517 ZFP1 NonAssociatedWithProgression
ENSG00000184939 ZFP90 +o+
ENSG00000187626 ZKSCAN4 NonAssociatedWithProgression
ENSG00000196652 ZKSCAN5 o--b
ENSG00000197020 ZNF100 NonAssociatedWithProgression
ENSG00000164631 ZNF12 NonAssociatedWithProgression
ENSG00000196418 ZNF124 NonAssociatedWithProgression
ENSG00000125846 ZNF133 o++a
ENSG00000196646 ZNF136 NonAssociatedWithProgression
ENSG00000197008 ZNF138 o+o
ENSG00000105708 ZNF14 NonAssociatedWithProgression
ENSG00000196387 ZNF140 NonAssociatedWithProgression
ENSG00000204920 ZNF155 o--a
ENSG00000196345 ZNF167 oo+
ENSG00000154957 ZNF18 o--a
ENSG00000096654 ZNF184 +o+
ENSG00000136870 ZNF189 +o+
ENSG00000005801 ZNF195 NonAssociatedWithProgression
ENSG00000186448 ZNF197 +o+
ENSG00000010539 ZNF200 NonAssociatedWithProgression
ENSG00000166261 ZNF202 ---
ENSG00000121417 ZNF211 oo+
ENSG00000170260 ZNF212 o--b
ENSG00000085644 ZNF213 o-o
ENSG00000159885 ZNF222 o++b
ENSG00000186019 ZNF224 +o+
ENSG00000167380 ZNF226 +o+
ENSG00000131115 ZNF227 NonAssociatedWithProgression
ENSG00000167377 ZNF23 o+o
ENSG00000159915 ZNF233 o++a
ENSG00000159917 ZNF235 o+o
ENSG00000198105 ZNF248 NonAssociatedWithProgression
ENSG00000213096 ZNF254 NonAssociatedWithProgression
ENSG00000198393 ZNF26 NonAssociatedWithProgression
ENSG00000006194 ZNF263 o--a
ENSG00000083844 ZNF264 o--a
ENSG00000090612 ZNF268 +oo
ENSG00000198039 ZNF273 NonAssociatedWithProgression
ENSG00000171606 ZNF274 o--a
ENSG00000198538 ZNF28 NonAssociatedWithProgression
ENSG00000170265 ZNF282 o--b
ENSG00000187607 ZNF286A o+o
ENSG00000141040 ZNF287 +o+
ENSG00000166526 ZNF3 ---
ENSG00000089335 ZNF302 o+o
ENSG00000131845 ZNF304 +o+
ENSG00000130803 ZNF317 o--a
ENSG00000182986 ZNF320 o++b
ENSG00000130844 ZNF331 o+o
ENSG00000160961 ZNF333 +o+
ENSG00000130684 ZNF337 +-o
ENSG00000189180 ZNF33A o--a
ENSG00000196693 ZNF33B NonAssociatedWithProgression
ENSG00000196378 ZNF34 -o-
ENSG00000088876 ZNF343 NonAssociatedWithProgression
ENSG00000169131 ZNF354A o-o
ENSG00000075407 ZNF37A -oo
ENSG00000161298 ZNF382 o+-
ENSG00000160908 ZNF394 ---
ENSG00000197024 ZNF398 o-o
ENSG00000170954 ZNF415 o++b
ENSG00000083817 ZNF416 o-+
ENSG00000105136 ZNF419 o--b
ENSG00000197050 ZNF420 NonAssociatedWithProgression
ENSG00000140987 ZNF434 o--a
ENSG00000125945 ZNF436 +o+
ENSG00000197044 ZNF441 NonAssociatedWithProgression
ENSG00000198342 ZNF442 o++a
ENSG00000180855 ZNF443 o++b
ENSG00000185219 ZNF445 -oo
ENSG00000124459 ZNF45 o+o
ENSG00000204604 ZNF468 o+o
ENSG00000142528 ZNF473 o--b
ENSG00000198464 ZNF480 -o-
ENSG00000198298 ZNF485 +oo
ENSG00000196268 ZNF493 NonAssociatedWithProgression
ENSG00000162714 ZNF496 o--b
ENSG00000197037 ZNF498 o-o
ENSG00000081665 ZNF506 NonAssociatedWithProgression
ENSG00000081386 ZNF510 +-o
ENSG00000167555 ZNF528 o++a
ENSG00000186020 ZNF529 o--a
ENSG00000198131 ZNF544 NonAssociatedWithProgression
ENSG00000188785 ZNF548 +o+
ENSG00000178935 ZNF552 o--a
ENSG00000167785 ZNF558 ---
ENSG00000188321 ZNF559 NonAssociatedWithProgression
ENSG00000171469 ZNF561 NonAssociatedWithProgression
ENSG00000171466 ZNF562 NonAssociatedWithProgression
ENSG00000249709 ZNF564 NonAssociatedWithProgression
ENSG00000186017 ZNF566 NonAssociatedWithProgression
ENSG00000189042 ZNF567 NonAssociatedWithProgression
ENSG00000198453 ZNF568 -+o
ENSG00000196437 ZNF569 NonAssociatedWithProgression
ENSG00000180479 ZNF571 NonAssociatedWithProgression
ENSG00000171574 ZNF584 NonAssociatedWithProgression
ENSG00000083828 ZNF586 oo-
ENSG00000164048 ZNF589 +-o
ENSG00000196458 ZNF605 NonAssociatedWithProgression
ENSG00000166704 ZNF606 o++b
ENSG00000198182 ZNF607 o+o
ENSG00000167554 ZNF610 o++b
ENSG00000213020 ZNF611 NonAssociatedWithProgression
ENSG00000142556 ZNF614 NonAssociatedWithProgression
ENSG00000197619 ZNF615 NonAssociatedWithProgression
ENSG00000204611 ZNF616 NonAssociatedWithProgression
ENSG00000172888 ZNF621 NonAssociatedWithProgression
ENSG00000197566 ZNF624 NonAssociatedWithProgression
ENSG00000213297 ZNF625 +o+
ENSG00000198551 ZNF627 o+o
ENSG00000167528 ZNF641 NonAssociatedWithProgression
ENSG00000187815 ZNF642 o++b
ENSG00000187801 ZNF643 NonAssociatedWithProgression
ENSG00000197343 ZNF655 o++b
ENSG00000182141 ZNF708 NonAssociatedWithProgression
ENSG00000152439 ZNF773 o-o
ENSG00000146757 ZNF92 o+o