PEACHi
GeneSet hsa-miR-375_targets (TarBase_6beta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
UpRegulated -2.8 0.01801 199.0 72.0 53.82
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000100439 ABHD4 ---
ENSG00000138443 ABI2 o-o
ENSG00000123983 ACSL3 NonAssociatedWithProgression
ENSG00000068366 ACSL4 o+-
ENSG00000006831 ADIPOR2 oo-
ENSG00000139154 AEBP2 NonAssociatedWithProgression
ENSG00000155189 AGPAT5 -o-
ENSG00000135049 AGTPBP1 NonAssociatedWithProgression
ENSG00000168710 AHCYL1 -+o
ENSG00000118507 AKAP7 o++a
ENSG00000116127 ALMS1 NonAssociatedWithProgression
ENSG00000101935 AMMECR1 o--b
ENSG00000186106 ANKRD46 NonAssociatedWithProgression
ENSG00000138613 APH1B o++b
ENSG00000136044 APPL2 NonAssociatedWithProgression
ENSG00000198826 ARHGAP11A oo-
ENSG00000102931 ARL2BP o++b
ENSG00000029153 ARNTL2 oo+
ENSG00000197548 ATG7 ---
ENSG00000163512 AZI2 NonAssociatedWithProgression
ENSG00000030110 BAK1 o--b
ENSG00000198604 BAZ1A NonAssociatedWithProgression
ENSG00000142867 BCL10 o+o
ENSG00000171791 BCL2 NonAssociatedWithProgression
ENSG00000153094 BCL2L11 NonAssociatedWithProgression
ENSG00000164039 BDH2 o++b
ENSG00000023445 BIRC3 o++a
ENSG00000182919 C11orf54 o++b
ENSG00000133641 C12orf29 NonAssociatedWithProgression
ENSG00000133943 C14orf159 o++a
ENSG00000186073 C15orf41 o++a
ENSG00000106392 C1GALT1 o++b
ENSG00000108561 C1QBP NonAssociatedWithProgression
ENSG00000174007 C3orf34 +o+
ENSG00000135932 CAB39 +o+
ENSG00000128595 CALU o--b
ENSG00000105483 CARD8 o++a
ENSG00000164305 CASP3 o++b
ENSG00000136682 CBWD2 -+o
ENSG00000196873 CBWD3 o++b
ENSG00000070831 CDC42 +oo
ENSG00000164649 CDCA7L o-o
ENSG00000140743 CDR2 o--b
ENSG00000117724 CENPF o--a
ENSG00000114107 CEP70 NonAssociatedWithProgression
ENSG00000165410 CFL2 o--a
ENSG00000123989 CHPF ---
ENSG00000111666 CHPT1 o++b
ENSG00000131873 CHSY1 o-+
ENSG00000136108 CKAP2 NonAssociatedWithProgression
ENSG00000111726 CMAS o+o
ENSG00000183723 CMTM4 NonAssociatedWithProgression
ENSG00000117519 CNN3 NonAssociatedWithProgression
ENSG00000135775 COG2 o--a
ENSG00000110880 CORO1C +oo
ENSG00000080819 CPOX NonAssociatedWithProgression
ENSG00000107175 CREB3 NonAssociatedWithProgression
ENSG00000176390 CRLF3 NonAssociatedWithProgression
ENSG00000101811 CSTF2 o-o
ENSG00000175215 CTDSP2 o-+
ENSG00000109861 CTSC o++a
ENSG00000166266 CUL5 o--b
ENSG00000154639 CXADR NonAssociatedWithProgression
ENSG00000119004 CYP20A1 oo-
ENSG00000155016 CYP2U1 NonAssociatedWithProgression
ENSG00000183283 DAZAP2 o-o
ENSG00000166847 DCTN5 o--a
ENSG00000109184 DCUN1D4 NonAssociatedWithProgression
ENSG00000077044 DGKD NonAssociatedWithProgression
ENSG00000151240 DIP2C NonAssociatedWithProgression
ENSG00000132535 DLG4 ---
ENSG00000105877 DNAH11 ---
ENSG00000126698 DNAJC8 NonAssociatedWithProgression
ENSG00000173852 DPY19L1 -+o
ENSG00000117505 DR1 o--a
ENSG00000139318 DUSP6 NonAssociatedWithProgression
ENSG00000128951 DUT o--a
ENSG00000147654 EBAG9 NonAssociatedWithProgression
ENSG00000123179 EBPL NonAssociatedWithProgression
ENSG00000102189 EEA1 NonAssociatedWithProgression
ENSG00000125266 EFNB2 o-o
ENSG00000108883 EFTUD2 -o-
ENSG00000055332 EIF2AK2 o--a
ENSG00000134001 EIF2S1 o--a
ENSG00000148730 EIF4EBP2 NonAssociatedWithProgression
ENSG00000075151 EIF4G3 NonAssociatedWithProgression
ENSG00000154380 ENAH o++b
ENSG00000145293 ENOPH1 NonAssociatedWithProgression
ENSG00000174371 EXO1 o++b
ENSG00000138190 EXOC6 o--b
ENSG00000103876 FAH o-o
ENSG00000155744 FAM126B o--a
ENSG00000203667 FAM36A o+o
ENSG00000196937 FAM3C o+o
ENSG00000128923 FAM63B NonAssociatedWithProgression
ENSG00000166797 FAM96A o++a
ENSG00000164117 FBXO8 o++b
ENSG00000088832 FKBP1A ---
ENSG00000070404 FSTL3 ---
ENSG00000122068 FYTTD1 o+o
ENSG00000141013 GAS8 NonAssociatedWithProgression
ENSG00000157259 GATAD1 NonAssociatedWithProgression
ENSG00000104381 GDAP1 NonAssociatedWithProgression
ENSG00000164347 GFM2 NonAssociatedWithProgression
ENSG00000165113 GKAP1 NonAssociatedWithProgression
ENSG00000144674 GOLGA4 NonAssociatedWithProgression
ENSG00000180758 GPR157 o-o
ENSG00000164284 GRPEL2 o-o
ENSG00000107937 GTPBP4 o--b
ENSG00000051108 HERPUD1 +oo
ENSG00000164683 HEY1 +o+
ENSG00000159399 HK2 o--b
ENSG00000189159 HN1 o-+
ENSG00000132541 HRSP12 o++a
ENSG00000080824 HSP90AA1 NonAssociatedWithProgression
ENSG00000126709 IFI6 oo+
ENSG00000068885 IFT80 -+o
ENSG00000177663 IL17RA NonAssociatedWithProgression
ENSG00000196083 IL1RAP o+o
ENSG00000125629 INSIG2 o-+
ENSG00000150093 ITGB1 NonAssociatedWithProgression
ENSG00000096968 JAK2 o++a
ENSG00000110906 KCTD10 NonAssociatedWithProgression
ENSG00000138030 KHK ---
ENSG00000170871 KIAA0232 NonAssociatedWithProgression
ENSG00000135709 KIAA0513 -+o
ENSG00000122203 KIAA1191 o--b
ENSG00000163507 KIAA1524 o+-
ENSG00000164118 KIAA1712 o++b
ENSG00000185909 KLHDC8B ---
ENSG00000122550 KLHL7 o+o
ENSG00000186432 KPNA4 NonAssociatedWithProgression
ENSG00000111716 LDHB o-o
ENSG00000104660 LEPROTL1 o-o
ENSG00000189067 LITAF o++a
ENSG00000169223 LMAN2 o--b
ENSG00000161654 LSM12 o--b
ENSG00000065559 MAP2K4 NonAssociatedWithProgression
ENSG00000119487 MAPKAP1 o--a
ENSG00000038274 MAT2B o+o
ENSG00000134046 MBD2 ---
ENSG00000159479 MED8 o--b
ENSG00000165055 METTL2B NonAssociatedWithProgression
ENSG00000133606 MKRN1 o--b
ENSG00000106330 MOSPD3 o--a
ENSG00000072415 MPP5 NonAssociatedWithProgression
ENSG00000153029 MR1 NonAssociatedWithProgression
ENSG00000118242 MREG o++b
ENSG00000147649 MTDH o--b
ENSG00000105887 MTPN NonAssociatedWithProgression
ENSG00000185697 MYBL1 o++a
ENSG00000103174 NAGPA NonAssociatedWithProgression
ENSG00000111912 NCOA7 oo+
ENSG00000070614 NDST1 NonAssociatedWithProgression
ENSG00000100503 NIN oo+
ENSG00000073536 NLE1 o--b
ENSG00000166197 NOLC1 o--b
ENSG00000115216 NRBP1 ---
ENSG00000088833 NSFL1C ---
ENSG00000076685 NT5C2 o--b
ENSG00000167005 NUDT21 NonAssociatedWithProgression
ENSG00000139496 NUPL1 +-o
ENSG00000153989 NUS1 NonAssociatedWithProgression
ENSG00000101888 NXT2 NonAssociatedWithProgression
ENSG00000136811 ODF2 o--b
ENSG00000087263 OGFOD1 NonAssociatedWithProgression
ENSG00000198836 OPA1 o-+
ENSG00000091039 OSBPL8 o-o
ENSG00000115507 OTX1 NonAssociatedWithProgression
ENSG00000154814 OXNAD1 +o+
ENSG00000007168 PAFAH1B1 o+-
ENSG00000158006 PAFAH2 o++b
ENSG00000164329 PAPD4 NonAssociatedWithProgression
ENSG00000170915 PAQR8 +o+
ENSG00000143799 PARP1 o--b
ENSG00000163346 PBXIP1 o--b
ENSG00000180628 PCGF5 NonAssociatedWithProgression
ENSG00000152256 PDK1 NonAssociatedWithProgression
ENSG00000089220 PEBP1 NonAssociatedWithProgression
ENSG00000169299 PGM2 o-+
ENSG00000129292 PHF20L1 o++b
ENSG00000118482 PHF3 NonAssociatedWithProgression
ENSG00000139289 PHLDA1 o++b
ENSG00000006576 PHTF2 +o+
ENSG00000069943 PIGB o++b
ENSG00000116095 PLEKHA3 -oo
ENSG00000127125 PPCS o++a
ENSG00000184203 PPP1R2 NonAssociatedWithProgression
ENSG00000092020 PPP2R3C o++b
ENSG00000117450 PRDX1 --o
ENSG00000165672 PRDX3 o+o
ENSG00000154229 PRKCA oo+
ENSG00000183943 PRKX o--b
ENSG00000164985 PSIP1 o-o
ENSG00000068878 PSME4 o--b
ENSG00000184007 PTP4A2 o--a
ENSG00000110536 PTPMT1 o-+
ENSG00000196396 PTPN1 +oo
ENSG00000127947 PTPN12 +oo
ENSG00000084733 RAB10 NonAssociatedWithProgression
ENSG00000157869 RAB28 o--b
ENSG00000175582 RAB6A o++b
ENSG00000123728 RAP2C o++b
ENSG00000107263 RAPGEF1 NonAssociatedWithProgression
ENSG00000123094 RASSF8 o+-
ENSG00000023287 RB1CC1 o+o
ENSG00000101773 RBBP8 NonAssociatedWithProgression
ENSG00000168214 RBPJ o--b
ENSG00000117906 RCN2 NonAssociatedWithProgression
ENSG00000072042 RDH11 o--a
ENSG00000145331 RG9MTD2 -+o
ENSG00000067560 RHOA o-o
ENSG00000119729 RHOQ o+o
ENSG00000117016 RIMS3 NonAssociatedWithProgression
ENSG00000117000 RLF o-o
ENSG00000156313 RPGR NonAssociatedWithProgression
ENSG00000103494 RPGRIP1L NonAssociatedWithProgression
ENSG00000163902 RPN1 o-o
ENSG00000118705 RPN2 o--a
ENSG00000165526 RPUSD4 o--b
ENSG00000083750 RRAGB o-+
ENSG00000116954 RRAGC +o+
ENSG00000125744 RTN2 o--a
ENSG00000132330 SCLY o++a
ENSG00000100934 SEC23A o++b
ENSG00000176986 SEC24C ---
ENSG00000079387 SENP1 o+-
ENSG00000120742 SERP1 --o
ENSG00000179833 SERTAD2 NonAssociatedWithProgression
ENSG00000119335 SET o--b
ENSG00000145391 SETD7 o++a
ENSG00000183955 SETD8 o--b
ENSG00000213064 SFT2D2 +o+
ENSG00000163535 SGOL2 NonAssociatedWithProgression
ENSG00000105738 SIPA1L3 -+o
ENSG00000102743 SLC25A15 NonAssociatedWithProgression
ENSG00000181035 SLC25A42 +o+
ENSG00000117620 SLC35A3 NonAssociatedWithProgression
ENSG00000205060 SLC35B4 NonAssociatedWithProgression
ENSG00000163798 SLC4A1AP o+o
ENSG00000131389 SLC6A6 o+o
ENSG00000103064 SLC7A6 o--b
ENSG00000131876 SNRPA1 o--b
ENSG00000109762 SNX25 o++a
ENSG00000135899 SP110 NonAssociatedWithProgression
ENSG00000008294 SPAG9 oo-
ENSG00000211455 STK38L NonAssociatedWithProgression
ENSG00000165209 STRBP --o
ENSG00000166900 STX3 -+o
ENSG00000113387 SUB1 +-o
ENSG00000178691 SUZ12 o--b
ENSG00000135316 SYNCRIP o--b
ENSG00000165632 TAF3 o--a
ENSG00000131374 TBC1D5 NonAssociatedWithProgression
ENSG00000140262 TCF12 o--a
ENSG00000101158 TH1L o--b
ENSG00000126351 THRA --o
ENSG00000134375 TIMM17A -oo
ENSG00000117500 TMED5 o+o
ENSG00000106460 TMEM106B o++b
ENSG00000125037 TMEM111 NonAssociatedWithProgression
ENSG00000149582 TMEM25 -+o
ENSG00000155099 TMEM55A NonAssociatedWithProgression
ENSG00000125247 TMTC4 --o
ENSG00000064419 TNPO3 NonAssociatedWithProgression
ENSG00000169905 TOR1AIP2 NonAssociatedWithProgression
ENSG00000047410 TPR o+-
ENSG00000196428 TSC22D2 o+-
ENSG00000165914 TTC7B -+o
ENSG00000114062 UBE3A NonAssociatedWithProgression
ENSG00000164332 UBLCP1 NonAssociatedWithProgression
ENSG00000118939 UCHL3 NonAssociatedWithProgression
ENSG00000148154 UGCG o+o
ENSG00000162607 USP1 o--b
ENSG00000103194 USP10 NonAssociatedWithProgression
ENSG00000103404 USP31 NonAssociatedWithProgression
ENSG00000109189 USP46 o++a
ENSG00000115652 UXS1 NonAssociatedWithProgression
ENSG00000144560 VGLL4 o--a
ENSG00000071127 WDR1 NonAssociatedWithProgression
ENSG00000147548 WHSC1L1 o--b
ENSG00000146457 WTAP o-o
ENSG00000143324 XPR1 -+o
ENSG00000164924 YWHAZ o--b
ENSG00000214717 ZBED1 ---
ENSG00000105939 ZC3HAV1 +-o
ENSG00000152518 ZFP36L2 NonAssociatedWithProgression
ENSG00000186660 ZFP91 +-o
ENSG00000180479 ZNF571 NonAssociatedWithProgression
ENSG00000142556 ZNF614 NonAssociatedWithProgression
ENSG00000229809 ZNF688 o-+