PEACHi
GeneSet hsa-miR-34a-5p_targets (TarBase_6beta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -4.5 0.004 216.0 51.0 29.84
DownRegulated -4.8 2.7E-4 216.0 156.0 127.56
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000151726 ACSL1 NonAssociatedWithProgression
ENSG00000068366 ACSL4 o+-
ENSG00000154930 ACSS1 ---
ENSG00000101126 ADNP NonAssociatedWithProgression
ENSG00000169129 AFAP1L2 NonAssociatedWithProgression
ENSG00000106305 AIMP2 NonAssociatedWithProgression
ENSG00000117448 AKR1A1 ---
ENSG00000053371 AKR7A2 o-o
ENSG00000143149 ALDH9A1 o--b
ENSG00000196975 ANXA4 NonAssociatedWithProgression
ENSG00000196961 AP2A1 ---
ENSG00000006125 AP2B1 ---
ENSG00000161203 AP2M1 ---
ENSG00000164062 APEH o-o
ENSG00000165527 ARF6 NonAssociatedWithProgression
ENSG00000175220 ARHGAP1 NonAssociatedWithProgression
ENSG00000168488 ATXN2L ---
ENSG00000158850 B4GALT3 o--a
ENSG00000204463 BAT3 ---
ENSG00000171791 BCL2 NonAssociatedWithProgression
ENSG00000099968 BCL2L13 oo+
ENSG00000029363 BCLAF1 NonAssociatedWithProgression
ENSG00000134717 BTF3L4 NonAssociatedWithProgression
ENSG00000197771 C10orf119 o+-
ENSG00000078237 C12orf5 o++b
ENSG00000120685 C13orf23 o--a
ENSG00000084774 CAD o--a
ENSG00000171735 CAMTA1 o-o
ENSG00000014216 CAPN1 ---
ENSG00000135387 CAPRIN1 -o-
ENSG00000077549 CAPZB o--b
ENSG00000163660 CCNL1 NonAssociatedWithProgression
ENSG00000026508 CD44 o++b
ENSG00000094880 CDC23 NonAssociatedWithProgression
ENSG00000096401 CDC5L NonAssociatedWithProgression
ENSG00000135446 CDK4 o--a
ENSG00000105810 CDK6 o--a
ENSG00000168564 CDKN2AIP NonAssociatedWithProgression
ENSG00000123080 CDKN2C o-o
ENSG00000172757 CFL1 o-o
ENSG00000085872 CHERP o-o
ENSG00000175216 CKAP5 NonAssociatedWithProgression
ENSG00000175416 CLTB ---
ENSG00000111726 CMAS o+o
ENSG00000162368 CMPK1 NonAssociatedWithProgression
ENSG00000172725 CORO1B o--b
ENSG00000157184 CPT2 o-+
ENSG00000168036 CTNNB1 o--b
ENSG00000085733 CTTN o--b
ENSG00000103018 CYB5B o+-
ENSG00000179958 DCTPP1 o--a
ENSG00000178105 DDX10 +o+
ENSG00000165732 DDX21 -o-
ENSG00000089737 DDX24 NonAssociatedWithProgression
ENSG00000136271 DDX56 o--b
ENSG00000172893 DHCR7 o--b
ENSG00000140829 DHX38 o--a
ENSG00000105993 DNAJB6 o+-
ENSG00000185721 DRG1 NonAssociatedWithProgression
ENSG00000096696 DSP NonAssociatedWithProgression
ENSG00000168393 DTYMK o-o
ENSG00000128951 DUT o--a
ENSG00000112242 E2F3 NonAssociatedWithProgression
ENSG00000122882 ECD +-o
ENSG00000142634 EFHD2 o-o
ENSG00000110047 EHD1 ---
ENSG00000114867 EIF4G1 ---
ENSG00000079819 EPB41L2 o-o
ENSG00000177106 EPS8L2 --o
ENSG00000186871 ERCC6L o-o
ENSG00000107566 ERLIN1 o-o
ENSG00000147475 ERLIN2 o+o
ENSG00000117868 ESYT2 o++b
ENSG00000103876 FAH o-o
ENSG00000133193 FAM104A o--a
ENSG00000196937 FAM3C o+o
ENSG00000009780 FAM76A o++b
ENSG00000168496 FEN1 NonAssociatedWithProgression
ENSG00000114861 FOXP1 oo-
ENSG00000172728 FUT10 o++a
ENSG00000114416 FXR1 ---
ENSG00000138757 G3BP2 NonAssociatedWithProgression
ENSG00000165219 GAPVD1 NonAssociatedWithProgression
ENSG00000180447 GAS1 o++b
ENSG00000006007 GDE1 o--a
ENSG00000203879 GDI1 o-o
ENSG00000082516 GEMIN5 NonAssociatedWithProgression
ENSG00000198380 GFPT1 NonAssociatedWithProgression
ENSG00000204120 GIGYF2 NonAssociatedWithProgression
ENSG00000113552 GNPDA1 o++a
ENSG00000115806 GORASP2 ---
ENSG00000177885 GRB2 NonAssociatedWithProgression
ENSG00000077235 GTF3C1 o--b
ENSG00000119041 GTF3C3 -oo
ENSG00000163754 GYG1 -oo
ENSG00000184897 H1FX o--a
ENSG00000163041 H3F3A NonAssociatedWithProgression
ENSG00000132475 H3F3B o--b
ENSG00000116478 HDAC1 ---
ENSG00000115677 HDLBP o--a
ENSG00000187837 HIST1H1C o--b
ENSG00000124575 HIST1H1D ---
ENSG00000137259 HIST1H2AB oo-
ENSG00000180573 HIST1H2AC NonAssociatedWithProgression
ENSG00000196787 HIST1H2AG NonAssociatedWithProgression
ENSG00000196747 HIST1H2AI ---
ENSG00000198374 HIST1H2AL ---
ENSG00000233224 HIST1H2AM o--b
ENSG00000196226 HIST1H2BB o--b
ENSG00000197409 HIST1H3D +-o
ENSG00000196176 HIST1H4A ---
ENSG00000124529 HIST1H4B +-o
ENSG00000188987 HIST1H4D o--a
ENSG00000197238 HIST1H4J o-+
ENSG00000197914 HIST1H4K o-+
ENSG00000198558 HIST1H4L NonAssociatedWithProgression
ENSG00000183558 HIST2H2AA3 o--b
ENSG00000203812 HIST2H2AA4 o--b
ENSG00000184678 HIST2H2BE NonAssociatedWithProgression
ENSG00000183941 HIST2H4A ---
ENSG00000182217 HIST2H4B o--b
ENSG00000105323 HNRNPUL1 o--b
ENSG00000072506 HSD17B10 o--b
ENSG00000204389 HSPA1A o--b
ENSG00000204388 HSPA1B o--b
ENSG00000086758 HUWE1 o-o
ENSG00000136231 IGF2BP3 o-+
ENSG00000113141 IK o--a
ENSG00000132305 IMMT NonAssociatedWithProgression
ENSG00000177971 IMP3 o--a
ENSG00000106348 IMPDH1 o--a
ENSG00000091409 ITGA6 NonAssociatedWithProgression
ENSG00000165572 KBTBD6 o-+
ENSG00000164961 KIAA0196 o++b
ENSG00000138160 KIF11 o+-
ENSG00000068796 KIF2A o+o
ENSG00000142945 KIF2C o--b
ENSG00000090889 KIF4A NonAssociatedWithProgression
ENSG00000170759 KIF5B NonAssociatedWithProgression
ENSG00000114030 KPNA1 NonAssociatedWithProgression
ENSG00000126777 KTN1 NonAssociatedWithProgression
ENSG00000155506 LARP1 o--b
ENSG00000134333 LDHA +-o
ENSG00000138795 LEF1 -o-
ENSG00000139233 LLPH o--a
ENSG00000066557 LRRC40 o+o
ENSG00000135341 MAP3K7 NonAssociatedWithProgression
ENSG00000047849 MAP4 o-+
ENSG00000073111 MCM2 o--a
ENSG00000104738 MCM4 o--a
ENSG00000100297 MCM5 o--b
ENSG00000076003 MCM6 o--a
ENSG00000166508 MCM7 o--b
ENSG00000164024 METAP1 o--b
ENSG00000148773 MKI67 o--a
ENSG00000155229 MMS19 o--b
ENSG00000155363 MOV10 ---
ENSG00000125901 MRPS26 o--b
ENSG00000149480 MTA2 ---
ENSG00000099810 MTAP -o-
ENSG00000147649 MTDH o--b
ENSG00000104643 MTMR9 +oo
ENSG00000136997 MYC o--b
ENSG00000197879 MYO1C ---
ENSG00000132780 NASP o--a
ENSG00000109805 NCAPG +-o
ENSG00000114503 NCBP2 o--b
ENSG00000104419 NDRG1 o--b
ENSG00000112992 NNT -+o
ENSG00000076685 NT5C2 o--b
ENSG00000069275 NUCKS1 ---
ENSG00000108256 NUFIP2 --o
ENSG00000213024 NUP62 o--a
ENSG00000110713 NUP98 o--a
ENSG00000087263 OGFOD1 NonAssociatedWithProgression
ENSG00000119403 PHF19 NonAssociatedWithProgression
ENSG00000143442 POGZ NonAssociatedWithProgression
ENSG00000062822 POLD1 o--a
ENSG00000181222 POLR2A ---
ENSG00000104356 POP1 o+o
ENSG00000143190 POU2F1 NonAssociatedWithProgression
ENSG00000214517 PPME1 o--b
ENSG00000221823 PPP3R1 +oo
ENSG00000198056 PRIM1 ---
ENSG00000137492 PRKRIR NonAssociatedWithProgression
ENSG00000147471 PROSC -+o
ENSG00000196504 PRPF40A -o-
ENSG00000159335 PTMS o--a
ENSG00000055917 PUM2 o-o
ENSG00000091127 PUS7 NonAssociatedWithProgression
ENSG00000241945 PWP2 NonAssociatedWithProgression
ENSG00000183010 PYCR1 o-o
ENSG00000100994 PYGB ---
ENSG00000151552 QDPR NonAssociatedWithProgression
ENSG00000118873 RAB3GAP2 ---
ENSG00000101146 RAE1 -o-
ENSG00000244462 RBM12 o--b
ENSG00000139746 RBM26 NonAssociatedWithProgression
ENSG00000049449 RCN1 o-+
ENSG00000072042 RDH11 o--a
ENSG00000103549 RNF40 o--a
ENSG00000153574 RPIA o--a
ENSG00000126458 RRAS NonAssociatedWithProgression
ENSG00000125844 RRBP1 ---
ENSG00000171848 RRM2 o--a
ENSG00000160208 RRP1B o--a
ENSG00000148484 RSU1 -oo
ENSG00000115310 RTN4 +oo
ENSG00000196754 S100A2 +o+
ENSG00000119042 SATB2 -+o
ENSG00000079387 SENP1 o+-
ENSG00000021355 SERPINB1 o++a
ENSG00000183576 SETD3 -o-
ENSG00000126821 SGPP1 o-+
ENSG00000142669 SH3BGRL3 o--b
ENSG00000096717 SIRT1 +-o
ENSG00000105281 SLC1A5 o--b
ENSG00000059804 SLC2A3 NonAssociatedWithProgression
ENSG00000033867 SLC4A7 oo+
ENSG00000127616 SMARCA4 o--b
ENSG00000173473 SMARCC1 o--a
ENSG00000139613 SMARCC2 --o
ENSG00000092531 SNAP23 o+o
ENSG00000147164 SNX12 o--b
ENSG00000180008 SOCS4 +o+
ENSG00000134243 SORT1 o-+
ENSG00000197694 SPTAN1 NonAssociatedWithProgression
ENSG00000115306 SPTBN1 oo-
ENSG00000167978 SRRM2 o--a
ENSG00000101972 STAG2 o--b
ENSG00000174353 STAG3L3 NonAssociatedWithProgression
ENSG00000115415 STAT1 oo+
ENSG00000023734 STRAP o--b
ENSG00000196235 SUPT5H o--b
ENSG00000148248 SURF4 o--b
ENSG00000054654 SYNE2 o--b
ENSG00000157014 TATDN2 o--a
ENSG00000183751 TBL3 o--b
ENSG00000070814 TCOF1 o--b
ENSG00000072274 TFRC o++a
ENSG00000101158 TH1L o--b
ENSG00000125676 THOC2 oo-
ENSG00000119139 TJP2 o++b
ENSG00000110108 TMEM109 o-o
ENSG00000128872 TMOD2 -+o
ENSG00000083312 TNPO1 oo-
ENSG00000064419 TNPO3 NonAssociatedWithProgression
ENSG00000130204 TOMM40 o--a
ENSG00000076554 TPD52 +oo
ENSG00000140416 TPM1 oo+
ENSG00000211460 TSN NonAssociatedWithProgression
ENSG00000108219 TSPAN14 ---
ENSG00000100304 TTLL12 o--a
ENSG00000198431 TXNRD1 o+o
ENSG00000176890 TYMS NonAssociatedWithProgression
ENSG00000137073 UBAP2 o--a
ENSG00000108106 UBE2S o--a
ENSG00000009335 UBE3C o--a
ENSG00000153560 UBP1 o-+
ENSG00000188021 UBQLN2 +oo
ENSG00000127481 UBR4 o-o
ENSG00000034063 UHRF1 o--b
ENSG00000156697 UTP14A NonAssociatedWithProgression
ENSG00000035403 VCL o++a
ENSG00000139722 VPS37B o--b
ENSG00000136631 VPS45 o++b
ENSG00000158195 WASF2 NonAssociatedWithProgression
ENSG00000084463 WBP11 o--b
ENSG00000073050 XRCC1 ---
ENSG00000114127 XRN1 o++b
ENSG00000100811 YY1 o--b
ENSG00000115085 ZAP70 o--b
ENSG00000130749 ZC3H4 NonAssociatedWithProgression
ENSG00000056097 ZFR o--b
ENSG00000122482 ZNF644 NonAssociatedWithProgression