PEACHi
GeneSet hsa-miR-21-5p_targets (TarBase_6beta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
+o+ -4.6 0.004 218.0 22.0 8.89
UpRegulated -7.1 0.0 218.0 94.0 58.95
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000117528 ABCD3 NonAssociatedWithProgression
ENSG00000075239 ACAT1 NonAssociatedWithProgression
ENSG00000107897 ACBD5 o--b
ENSG00000138071 ACTR2 o+o
ENSG00000101126 ADNP NonAssociatedWithProgression
ENSG00000119844 AFTPH NonAssociatedWithProgression
ENSG00000164252 AGGF1 +o+
ENSG00000173209 AHSA2 o++b
ENSG00000112297 AIM1 +o+
ENSG00000127914 AKAP9 NonAssociatedWithProgression
ENSG00000116127 ALMS1 NonAssociatedWithProgression
ENSG00000003393 ALS2 o++b
ENSG00000206560 ANKRD28 +o+
ENSG00000185009 AP3M1 o--a
ENSG00000120868 APAF1 o++b
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000178878 APOLD1 oo+
ENSG00000157500 APPL1 o+o
ENSG00000066777 ARFGEF1 NonAssociatedWithProgression
ENSG00000107863 ARHGAP21 +o+
ENSG00000032219 ARID4A o-+
ENSG00000102401 ARMCX3 o++b
ENSG00000162174 ASRGL1 NonAssociatedWithProgression
ENSG00000119778 ATAD2B NonAssociatedWithProgression
ENSG00000115966 ATF2 NonAssociatedWithProgression
ENSG00000166454 ATMIN o++b
ENSG00000058063 ATP11B NonAssociatedWithProgression
ENSG00000058668 ATP2B4 o++b
ENSG00000085224 ATRX -oo
ENSG00000158321 AUTS2 o++b
ENSG00000009954 BAZ1B oo-
ENSG00000060982 BCAT1 +-o
ENSG00000164039 BDH2 o++b
ENSG00000015475 BID -oo
ENSG00000204217 BMPR2 NonAssociatedWithProgression
ENSG00000012048 BRCA1 NonAssociatedWithProgression
ENSG00000204256 BRD2 o--b
ENSG00000100916 BRMS1L o--b
ENSG00000132640 BTBD3 o+o
ENSG00000011114 BTBD7 NonAssociatedWithProgression
ENSG00000159388 BTG2 o-o
ENSG00000174718 C12orf35 +-o
ENSG00000120685 C13orf23 o--a
ENSG00000141034 C17orf39 o--a
ENSG00000196227 C20orf177 o++b
ENSG00000118961 C2orf43 NonAssociatedWithProgression
ENSG00000106771 C9orf5 ---
ENSG00000135387 CAPRIN1 -o-
ENSG00000175455 CCDC14 oo+
ENSG00000109881 CCDC34 NonAssociatedWithProgression
ENSG00000113328 CCNG1 +o+
ENSG00000196776 CD47 NonAssociatedWithProgression
ENSG00000164045 CDC25A o--b
ENSG00000111328 CDK2AP1 --o
ENSG00000105810 CDK6 o--a
ENSG00000119397 CEP110 +o+
ENSG00000175216 CKAP5 NonAssociatedWithProgression
ENSG00000171365 CLCN5 -+o
ENSG00000115295 CLIP4 o++a
ENSG00000106789 CORO2A NonAssociatedWithProgression
ENSG00000107864 CPEB3 o++b
ENSG00000113712 CSNK1A1 o+o
ENSG00000036257 CUL3 o--a
ENSG00000071967 CYBRD1 NonAssociatedWithProgression
ENSG00000145476 CYP4V2 NonAssociatedWithProgression
ENSG00000131002 CYorf15B oo+
ENSG00000100592 DAAM1 o++b
ENSG00000162290 DCP1A o+o
ENSG00000085788 DDHD2 NonAssociatedWithProgression
ENSG00000215301 DDX3X oo-
ENSG00000145833 DDX46 NonAssociatedWithProgression
ENSG00000075711 DLG1 NonAssociatedWithProgression
ENSG00000135164 DMTF1 NonAssociatedWithProgression
ENSG00000111817 DSE NonAssociatedWithProgression
ENSG00000163840 DTX3L oo+
ENSG00000184545 DUSP8 ---
ENSG00000135720 DYNC1LI2 NonAssociatedWithProgression
ENSG00000172071 EIF2AK3 NonAssociatedWithProgression
ENSG00000123908 EIF2C2 o--b
ENSG00000134698 EIF2C4 +o+
ENSG00000148730 EIF4EBP2 NonAssociatedWithProgression
ENSG00000100664 EIF5 o--b
ENSG00000118402 ELOVL4 +-o
ENSG00000154380 ENAH o++b
ENSG00000112425 EPM2A +oo
ENSG00000139163 ETNK1 o--a
ENSG00000070367 EXOC5 NonAssociatedWithProgression
ENSG00000162636 FAM102B o+o
ENSG00000155744 FAM126B o--a
ENSG00000116199 FAM20B o--b
ENSG00000196937 FAM3C o+o
ENSG00000128923 FAM63B NonAssociatedWithProgression
ENSG00000140525 FANCI o--b
ENSG00000026103 FAS NonAssociatedWithProgression
ENSG00000145743 FBXL17 -oo
ENSG00000118564 FBXL5 o-+
ENSG00000138081 FBXO11 +o+
ENSG00000110429 FBXO3 o+o
ENSG00000096060 FKBP5 o--b
ENSG00000102081 FMR1 o+-
ENSG00000187239 FNBP1 o--b
ENSG00000053254 FOXN3 oo+
ENSG00000162613 FUBP1 +oo
ENSG00000165219 GAPVD1 NonAssociatedWithProgression
ENSG00000106415 GLCCI1 o-o
ENSG00000090863 GLG1 o-+
ENSG00000156052 GNAQ oo+
ENSG00000114450 GNB4 -+o
ENSG00000159921 GNE NonAssociatedWithProgression
ENSG00000144674 GOLGA4 NonAssociatedWithProgression
ENSG00000119927 GPAM o-o
ENSG00000152642 GPD1L o++a
ENSG00000164284 GRPEL2 o-o
ENSG00000077809 GTF2I o+-
ENSG00000092148 HECTD1 NonAssociatedWithProgression
ENSG00000122557 HERPUD2 NonAssociatedWithProgression
ENSG00000029993 HMGB3 o--b
ENSG00000110756 HPS5 o++b
ENSG00000125430 HS3ST3B1 +o+
ENSG00000136381 IREB2 o--b
ENSG00000198399 ITSN2 o+o
ENSG00000116679 IVNS1ABP NonAssociatedWithProgression
ENSG00000104369 JPH1 NonAssociatedWithProgression
ENSG00000165572 KBTBD6 o-+
ENSG00000120696 KBTBD7 NonAssociatedWithProgression
ENSG00000144320 KIAA1715 NonAssociatedWithProgression
ENSG00000075945 KIFAP3 NonAssociatedWithProgression
ENSG00000102554 KLF5 o-+
ENSG00000087448 KLHDC5 NonAssociatedWithProgression
ENSG00000174010 KLHL15 NonAssociatedWithProgression
ENSG00000114796 KLHL24 o++b
ENSG00000146021 KLHL3 o++b
ENSG00000145332 KLHL8 NonAssociatedWithProgression
ENSG00000005893 LAMP2 o-+
ENSG00000133706 LARS NonAssociatedWithProgression
ENSG00000172292 LASS6 -+o
ENSG00000178177 LCORL +o+
ENSG00000148943 LIN7C NonAssociatedWithProgression
ENSG00000105983 LMBR1 -oo
ENSG00000123684 LPGAT1 o++b
ENSG00000134324 LPIN1 NonAssociatedWithProgression
ENSG00000186687 LYRM7 o++b
ENSG00000172175 MALT1 +o+
ENSG00000095015 MAP3K1 o--a
ENSG00000169967 MAP3K2 +o+
ENSG00000152601 MBNL1 NonAssociatedWithProgression
ENSG00000198625 MDM4 o-o
ENSG00000068305 MEF2A NonAssociatedWithProgression
ENSG00000143995 MEIS1 o++b
ENSG00000174197 MGA o+-
ENSG00000071073 MGAT4A NonAssociatedWithProgression
ENSG00000101752 MIB1 NonAssociatedWithProgression
ENSG00000099875 MKNK2 o--b
ENSG00000165943 MOAP1 NonAssociatedWithProgression
ENSG00000159256 MORC3 NonAssociatedWithProgression
ENSG00000072415 MPP5 NonAssociatedWithProgression
ENSG00000048544 MRPS10 -o-
ENSG00000095002 MSH2 +oo
ENSG00000150712 MTMR12 NonAssociatedWithProgression
ENSG00000104643 MTMR9 +oo
ENSG00000105887 MTPN NonAssociatedWithProgression
ENSG00000185499 MUC1 +-o
ENSG00000005810 MYCBP2 -+o
ENSG00000104177 MYEF2 NonAssociatedWithProgression
ENSG00000066933 MYO9A NonAssociatedWithProgression
ENSG00000083168 MYST3 +-o
ENSG00000172915 NBEA -+o
ENSG00000162736 NCSTN o--b
ENSG00000151414 NEK7 NonAssociatedWithProgression
ENSG00000102908 NFAT5 o--b
ENSG00000147862 NFIB NonAssociatedWithProgression
ENSG00000100503 NIN oo+
ENSG00000164190 NIPBL NonAssociatedWithProgression
ENSG00000114857 NKTR ---
ENSG00000177463 NR2C2 NonAssociatedWithProgression
ENSG00000076685 NT5C2 o--b
ENSG00000108256 NUFIP2 --o
ENSG00000070882 OSBPL3 NonAssociatedWithProgression
ENSG00000129116 PALLD NonAssociatedWithProgression
ENSG00000152520 PAN3 NonAssociatedWithProgression
ENSG00000143799 PARP1 o--b
ENSG00000138496 PARP9 NonAssociatedWithProgression
ENSG00000163939 PBRM1 NonAssociatedWithProgression
ENSG00000150593 PDCD4 oo-
ENSG00000198721 PECI o++a
ENSG00000197329 PELI1 NonAssociatedWithProgression
ENSG00000123836 PFKFB2 o+-
ENSG00000164040 PGRMC2 o--a
ENSG00000112419 PHACTR2 o++a
ENSG00000102221 PHF16 NonAssociatedWithProgression
ENSG00000077684 PHF17 o--b
ENSG00000025293 PHF20 o--a
ENSG00000129292 PHF20L1 o++b
ENSG00000146247 PHIP NonAssociatedWithProgression
ENSG00000116793 PHTF1 o+o
ENSG00000197563 PIGN --o
ENSG00000163964 PIGX o--a
ENSG00000011405 PIK3C2A o++b
ENSG00000145675 PIK3R1 o--a
ENSG00000118762 PKD2 oo+
ENSG00000160199 PKNOX1 o--b
ENSG00000107679 PLEKHA1 +o+
ENSG00000013503 POLR3B -+o
ENSG00000067113 PPAP2A o+-
ENSG00000186951 PPARA o++a
ENSG00000163590 PPM1L o++b
ENSG00000138078 PREPL o+o
ENSG00000131791 PRKAB2 NonAssociatedWithProgression
ENSG00000185246 PRPF39 NonAssociatedWithProgression
ENSG00000164244 PRRC1 o--b
ENSG00000134222 PSRC1 NonAssociatedWithProgression
ENSG00000188647 PTAR1 o+o
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000158079 PTPDC1 +o+
ENSG00000070159 PTPN3 NonAssociatedWithProgression
ENSG00000185129 PURA ---
ENSG00000146676 PURB o--a
ENSG00000107560 RAB11FIP2 NonAssociatedWithProgression
ENSG00000124209 RAB22A o+-
ENSG00000118873 RAB3GAP2 ---
ENSG00000175582 RAB6A o++b
ENSG00000222014 RAB6C o++b
ENSG00000011454 RABGAP1 o--a
ENSG00000116191 RALGPS2 oo+
ENSG00000158987 RAPGEF6 NonAssociatedWithProgression
ENSG00000172575 RASGRP1 -+o
ENSG00000091009 RBM27 oo-
ENSG00000072042 RDH11 o--a
ENSG00000122707 RECK NonAssociatedWithProgression
ENSG00000135945 REV1 ---
ENSG00000009413 REV3L o-o
ENSG00000164292 RHOBTB3 NonAssociatedWithProgression
ENSG00000119729 RHOQ o+o
ENSG00000153561 RMND5A NonAssociatedWithProgression
ENSG00000135828 RNASEL +o+
ENSG00000123091 RNF11 o++b
ENSG00000137075 RNF38 o--b
ENSG00000119314 ROD1 o--b
ENSG00000102218 RP2 o-o
ENSG00000251474 RPL32P3 o-o
ENSG00000177189 RPS6KA3 NonAssociatedWithProgression
ENSG00000116954 RRAGC +o+
ENSG00000048649 RSF1 +-o
ENSG00000159579 RSPRY1 o+o
ENSG00000137815 RTF1 NonAssociatedWithProgression
ENSG00000018189 RUFY3 -oo
ENSG00000211456 SACM1L o+o
ENSG00000079332 SAR1A NonAssociatedWithProgression
ENSG00000136193 SCRN1 --o
ENSG00000000457 SCYL3 o++b
ENSG00000025796 SEC63 o--a
ENSG00000163536 SERPINI1 -+o
ENSG00000187231 SESTD1 o-+
ENSG00000164466 SFXN1 --o
ENSG00000163069 SGCB NonAssociatedWithProgression
ENSG00000145604 SKP2 o++b
ENSG00000109171 SLAIN2 +-o
ENSG00000119899 SLC17A5 +o+
ENSG00000155850 SLC26A2 +o+
ENSG00000198743 SLC5A3 NonAssociatedWithProgression
ENSG00000198689 SLC9A6 NonAssociatedWithProgression
ENSG00000065613 SLK NonAssociatedWithProgression
ENSG00000163681 SLMAP o+o
ENSG00000072501 SMC1A o--a
ENSG00000198887 SMC5 NonAssociatedWithProgression
ENSG00000119953 SMNDC1 +oo
ENSG00000163788 SNRK o-o
ENSG00000071189 SNX13 NonAssociatedWithProgression
ENSG00000148158 SNX30 o-+
ENSG00000180008 SOCS4 +o+
ENSG00000171150 SOCS5 oo-
ENSG00000104133 SPG11 NonAssociatedWithProgression
ENSG00000106723 SPIN1 NonAssociatedWithProgression
ENSG00000135250 SRPK2 o-o
ENSG00000138434 SSFA2 o--b
ENSG00000073849 ST6GAL1 NonAssociatedWithProgression
ENSG00000101972 STAG2 o--b
ENSG00000168610 STAT3 o--b
ENSG00000165209 STRBP --o
ENSG00000164506 STXBP5 -+o
ENSG00000178691 SUZ12 o--b
ENSG00000054654 SYNE2 o--b
ENSG00000147526 TACC1 o+o
ENSG00000147133 TAF1 NonAssociatedWithProgression
ENSG00000148835 TAF5 o--a
ENSG00000177565 TBL1XR1 o-o
ENSG00000070759 TESK2 +o+
ENSG00000163513 TGFBR2 +o+
ENSG00000125676 THOC2 oo-
ENSG00000135048 TMEM2 NonAssociatedWithProgression
ENSG00000083312 TNPO1 oo-
ENSG00000100354 TNRC6B o+o
ENSG00000131747 TOP2A o--b
ENSG00000169905 TOR1AIP2 NonAssociatedWithProgression
ENSG00000140416 TPM1 oo+
ENSG00000196459 TRAPPC2 o++b
ENSG00000109654 TRIM2 o+o
ENSG00000197323 TRIM33 NonAssociatedWithProgression
ENSG00000213186 TRIM59 NonAssociatedWithProgression
ENSG00000092439 TRPM7 NonAssociatedWithProgression
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000121297 TSHZ3 +oo
ENSG00000211460 TSN NonAssociatedWithProgression
ENSG00000113638 TTC33 NonAssociatedWithProgression
ENSG00000114999 TTL NonAssociatedWithProgression
ENSG00000153575 TUBGCP5 o-o
ENSG00000104517 UBR5 +oo
ENSG00000115464 USP34 -o-
ENSG00000187555 USP7 ---
ENSG00000152818 UTRN -+o
ENSG00000143494 VASH2 o++b
ENSG00000197969 VPS13A NonAssociatedWithProgression
ENSG00000122958 VPS26A o+o
ENSG00000136100 VPS36 ---
ENSG00000006715 VPS41 NonAssociatedWithProgression
ENSG00000143952 VPS54 o--a
ENSG00000085433 WDR47 o-+
ENSG00000091157 WDR7 NonAssociatedWithProgression
ENSG00000109685 WHSC1 o--b
ENSG00000147548 WHSC1L1 o--b
ENSG00000060237 WNK1 NonAssociatedWithProgression
ENSG00000136758 YME1L1 NonAssociatedWithProgression
ENSG00000180667 YOD1 o--b
ENSG00000047188 YTHDC2 NonAssociatedWithProgression
ENSG00000196323 ZBTB44 NonAssociatedWithProgression
ENSG00000039319 ZFYVE16 +o+
ENSG00000121741 ZMYM2 NonAssociatedWithProgression
ENSG00000010244 ZNF207 NonAssociatedWithProgression
ENSG00000171940 ZNF217 o--b
ENSG00000187607 ZNF286A o+o
ENSG00000188994 ZNF292 NonAssociatedWithProgression
ENSG00000162664 ZNF326 o+o
ENSG00000165244 ZNF367 NonAssociatedWithProgression
ENSG00000019995 ZRANB1 NonAssociatedWithProgression
ENSG00000162378 ZYG11B NonAssociatedWithProgression