GeneSet TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D (TFmiRNA_Targets.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
+-o -5.1 0.01046 208.0 19.0 6.51
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000166016 ABTB2 NonAssociatedWithProgression
ENSG00000151726 ACSL1 NonAssociatedWithProgression
ENSG00000049192 ADAMTS6 o++a
ENSG00000197381 ADARB1 o++b
ENSG00000148926 ADM +oo
ENSG00000173020 ADRBK1 o--b
ENSG00000172493 AFF1 +-o
ENSG00000072364 AFF4 NonAssociatedWithProgression
ENSG00000204310 AGPAT1 o--b
ENSG00000117020 AKT3 o++b
ENSG00000118454 ANKRD13C oo-
ENSG00000198944 ANKRD43 NonAssociatedWithProgression
ENSG00000151458 ANKRD50 NonAssociatedWithProgression
ENSG00000166747 AP1G1 o+-
ENSG00000124198 ARFGEF2 o+o
ENSG00000102606 ARHGEF7 NonAssociatedWithProgression
ENSG00000162980 ARL5A NonAssociatedWithProgression
ENSG00000113369 ARRDC3 NonAssociatedWithProgression
ENSG00000057663 ATG5 +o+
ENSG00000101974 ATP11C o++b
ENSG00000143153 ATP1B1 -oo
ENSG00000174437 ATP2A2 -o-
ENSG00000070961 ATP2B1 +-o
ENSG00000157087 ATP2B2 o++b
ENSG00000124788 ATXN1 oo+
ENSG00000086062 B4GALT1 ---
ENSG00000112182 BACH2 +-o
ENSG00000175866 BAIAP2 NonAssociatedWithProgression
ENSG00000076108 BAZ2A o++b
ENSG00000123636 BAZ2B -+o
ENSG00000119866 BCL11A ---
ENSG00000153094 BCL2L11 NonAssociatedWithProgression
ENSG00000029363 BCLAF1 NonAssociatedWithProgression
ENSG00000115760 BIRC6 -+o
ENSG00000204217 BMPR2 NonAssociatedWithProgression
ENSG00000100425 BRD1 o--b
ENSG00000185658 BRWD1 NonAssociatedWithProgression
ENSG00000132640 BTBD3 o+o
ENSG00000156384 C10orf78 o++a
ENSG00000100744 C14orf129 o++b
ENSG00000119669 C14orf4 NonAssociatedWithProgression
ENSG00000156030 C14orf43 o--a
ENSG00000141034 C17orf39 o--a
ENSG00000117616 C1orf63 NonAssociatedWithProgression
ENSG00000112308 C6orf62 o-o
ENSG00000007402 CACNA2D2 NonAssociatedWithProgression
ENSG00000148660 CAMK2G o+o
ENSG00000130559 CAMSAP1 +-o
ENSG00000108509 CAMTA2 --o
ENSG00000198286 CARD11 ---
ENSG00000078699 CBFA2T2 o--a
ENSG00000129993 CBFA2T3 NonAssociatedWithProgression
ENSG00000114423 CBLB +oo
ENSG00000141582 CBX4 o+-
ENSG00000100307 CBX7 --o
ENSG00000060339 CCAR1 o--b
ENSG00000107443 CCNJ o--b
ENSG00000090061 CCNK +-o
ENSG00000010610 CD4 o--b
ENSG00000143776 CDC42BPA NonAssociatedWithProgression
ENSG00000134371 CDC73 o--b
ENSG00000153046 CDYL o--a
ENSG00000163320 CGGBP1 NonAssociatedWithProgression
ENSG00000171316 CHD7 o++b
ENSG00000177200 CHD9 o--a
ENSG00000074054 CLASP1 NonAssociatedWithProgression
ENSG00000108582 CPD o++a
ENSG00000113742 CPEB4 NonAssociatedWithProgression
ENSG00000118260 CREB1 o+-
ENSG00000169118 CSNK1G1 o--a
ENSG00000151292 CSNK1G3 o++b
ENSG00000144677 CTDSPL o++b
ENSG00000036257 CUL3 o--a
ENSG00000166266 CUL5 o--b
ENSG00000183283 DAZAP2 o-o
ENSG00000043093 DCUN1D1 ---
ENSG00000215301 DDX3X oo-
ENSG00000067048 DDX3Y NonAssociatedWithProgression
ENSG00000136986 DERL1 NonAssociatedWithProgression
ENSG00000066084 DIP2B NonAssociatedWithProgression
ENSG00000138246 DNAJC13 NonAssociatedWithProgression
ENSG00000116641 DOCK7 o++a
ENSG00000083097 DOPEY1 o-+
ENSG00000092964 DPYSL2 NonAssociatedWithProgression
ENSG00000138166 DUSP5 +-o
ENSG00000135720 DYNC1LI2 NonAssociatedWithProgression
ENSG00000133740 E2F5 o--b
ENSG00000165891 E2F7 NonAssociatedWithProgression
ENSG00000074266 EED o--a
ENSG00000156976 EIF4A2 o+o
ENSG00000154380 ENAH o++b
ENSG00000095203 EPB41L4B -oo
ENSG00000135999 EPC2 oo-
ENSG00000085832 EPS15 +-o
ENSG00000120705 ETF1 o--a
ENSG00000134954 ETS1 NonAssociatedWithProgression
ENSG00000139083 ETV6 o++a
ENSG00000196937 FAM3C o+o
ENSG00000148343 FAM73B NonAssociatedWithProgression
ENSG00000138081 FBXO11 +o+
ENSG00000165355 FBXO33 o+-
ENSG00000088832 FKBP1A ---
ENSG00000157827 FMNL2 o++b
ENSG00000102531 FNDC3A o+o
ENSG00000075420 FNDC3B +-o
ENSG00000170345 FOS NonAssociatedWithProgression
ENSG00000164916 FOXK1 +-o
ENSG00000114861 FOXP1 oo-
ENSG00000138757 G3BP2 NonAssociatedWithProgression
ENSG00000165219 GAPVD1 NonAssociatedWithProgression
ENSG00000165678 GHITM o+o
ENSG00000115419 GLS o--b
ENSG00000136935 GOLGA1 o++b
ENSG00000175265 GOLGA8A NonAssociatedWithProgression
ENSG00000215252 GOLGA8B o--a
ENSG00000062194 GPBP1 ---
ENSG00000152642 GPD1L o++a
ENSG00000106070 GRB10 oo-
ENSG00000112406 HECA +-o
ENSG00000169635 HIC2 o--a
ENSG00000164104 HMGB2 o--b
ENSG00000149428 HYOU1 o--b
ENSG00000129351 ILF3 -o-
ENSG00000068383 INPP5A -o-
ENSG00000148384 INPP5E o-+
ENSG00000185950 IRS2 NonAssociatedWithProgression
ENSG00000116679 IVNS1ABP NonAssociatedWithProgression
ENSG00000153814 JAZF1 ---
ENSG00000131149 KIAA0182 o--b
ENSG00000177728 KIAA0195 o--b
ENSG00000111731 KIAA0528 o--b
ENSG00000132361 KIAA0664 ---
ENSG00000168502 KIAA0802 o-+
ENSG00000050030 KIAA2022 +o+
ENSG00000067082 KLF6 +-o
ENSG00000109466 KLHL2 o++b
ENSG00000109790 KLHL5 o++b
ENSG00000114030 KPNA1 NonAssociatedWithProgression
ENSG00000108424 KPNB1 o--a
ENSG00000161813 LARP4 o+-
ENSG00000143815 LBR +oo
ENSG00000174106 LEMD3 +-o
ENSG00000148943 LIN7C NonAssociatedWithProgression
ENSG00000164187 LMBRD2 o++b
ENSG00000154359 LONRF1 +oo
ENSG00000145012 LPP oo+
ENSG00000198589 LRBA ---
ENSG00000147650 LRP12 o++b
ENSG00000175928 LRRN1 o+o
ENSG00000166963 MAP1A o--b
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000130758 MAP3K10 o--a
ENSG00000198909 MAP3K3 o-+
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000186868 MAPT o++a
ENSG00000168906 MAT2A ---
ENSG00000139793 MBNL2 NonAssociatedWithProgression
ENSG00000169057 MECP2 o--a
ENSG00000159479 MED8 o--b
ENSG00000164024 METAP1 o--b
ENSG00000141503 MINK1 o--b
ENSG00000099875 MKNK2 o--b
ENSG00000072415 MPP5 NonAssociatedWithProgression
ENSG00000150712 MTMR12 NonAssociatedWithProgression
ENSG00000104643 MTMR9 +oo
ENSG00000105887 MTPN NonAssociatedWithProgression
ENSG00000133026 MYH10 o--a
ENSG00000140396 NCOA2 NonAssociatedWithProgression
ENSG00000102908 NFAT5 o--b
ENSG00000164190 NIPBL NonAssociatedWithProgression
ENSG00000087095 NLK oo+
ENSG00000152465 NMT2 NonAssociatedWithProgression
ENSG00000141279 NPEPPS ---
ENSG00000177463 NR2C2 NonAssociatedWithProgression
ENSG00000113580 NR3C1 o--a
ENSG00000035681 NSMAF o--a
ENSG00000147162 OGT o-o
ENSG00000070882 OSBPL3 NonAssociatedWithProgression
ENSG00000091039 OSBPL8 o-o
ENSG00000164164 OTUD4 o+-
ENSG00000130669 PAK4 o--b
ENSG00000129116 PALLD NonAssociatedWithProgression
ENSG00000145730 PAM oo+
ENSG00000115421 PAPOLG o++b
ENSG00000177425 PAWR o++b
ENSG00000167081 PBX3 NonAssociatedWithProgression
ENSG00000056661 PCGF2 ---
ENSG00000081154 PCNP NonAssociatedWithProgression
ENSG00000143870 PDIA6 o-o
ENSG00000163110 PDLIM5 -+o
ENSG00000132326 PER2 +-o
ENSG00000043143 PHF15 o--b
ENSG00000129292 PHF20L1 o++b
ENSG00000118482 PHF3 NonAssociatedWithProgression
ENSG00000139289 PHLDA1 o++b
ENSG00000038210 PI4K2B o-+
ENSG00000073921 PICALM +o+
ENSG00000117461 PIK3R3 NonAssociatedWithProgression
ENSG00000181690 PLAG1 oo-
ENSG00000154822 PLCL2 o++a
ENSG00000116095 PLEKHA3 -oo
ENSG00000104886 PLEKHJ1 o-o
ENSG00000120756 PLS1 o++a
ENSG00000189266 PNRC2 o+o
ENSG00000196313 POM121 o--b
ENSG00000213639 PPP1CB +-o
ENSG00000077157 PPP1R12B -oo
ENSG00000221823 PPP3R1 +oo
ENSG00000163932 PRKCD NonAssociatedWithProgression
ENSG00000197746 PSAP oo-
ENSG00000134644 PUM1 o--a
ENSG00000146676 PURB o--a
ENSG00000112531 QKI NonAssociatedWithProgression
ENSG00000103769 RAB11A -o-
ENSG00000107560 RAB11FIP2 NonAssociatedWithProgression
ENSG00000154710 RABGEF1 NonAssociatedWithProgression
ENSG00000164754 RAD21 o--b
ENSG00000132341 RAN o--b
ENSG00000127314 RAP1B NonAssociatedWithProgression
ENSG00000102054 RBBP7 o-o
ENSG00000086589 RBM22 o--b
ENSG00000122707 RECK NonAssociatedWithProgression
ENSG00000117000 RLF o-o
ENSG00000170633 RNF34 NonAssociatedWithProgression
ENSG00000127870 RNF6 NonAssociatedWithProgression
ENSG00000101654 RNMT NonAssociatedWithProgression
ENSG00000119314 ROD1 o--b
ENSG00000177189 RPS6KA3 NonAssociatedWithProgression
ENSG00000108443 RPS6KB1 NonAssociatedWithProgression
ENSG00000081019 RSBN1 o-o
ENSG00000137815 RTF1 NonAssociatedWithProgression
ENSG00000159216 RUNX1 o--b
ENSG00000116497 S100PBP +o+
ENSG00000151967 SCHIP1 o++b
ENSG00000153130 SCOC NonAssociatedWithProgression
ENSG00000176986 SEC24C ---
ENSG00000095539 SEMA4G NonAssociatedWithProgression
ENSG00000079387 SENP1 o+-
ENSG00000163904 SENP2 o--a
ENSG00000100167 SEPT3 NonAssociatedWithProgression
ENSG00000096717 SIRT1 +-o
ENSG00000148339 SLC25A25 ---
ENSG00000147454 SLC25A37 ---
ENSG00000059804 SLC2A3 NonAssociatedWithProgression
ENSG00000134294 SLC38A2 oo-
ENSG00000198689 SLC9A6 NonAssociatedWithProgression
ENSG00000134278 SPIRE1 o++a
ENSG00000187678 SPRY4 +-o
ENSG00000135250 SRPK2 o-o
ENSG00000184402 SS18L1 o--b
ENSG00000117155 SSX2IP -o-
ENSG00000113532 ST8SIA4 o+o
ENSG00000118007 STAG1 NonAssociatedWithProgression
ENSG00000131018 SYNE1 o++b
ENSG00000157625 TAB3 o+o
ENSG00000120948 TARDBP o--a
ENSG00000065882 TBC1D1 NonAssociatedWithProgression
ENSG00000136111 TBC1D4 o++a
ENSG00000101849 TBL1X +-o
ENSG00000177565 TBL1XR1 o-o
ENSG00000028839 TBPL1 NonAssociatedWithProgression
ENSG00000113649 TCERG1 o--a
ENSG00000117500 TMED5 o+o
ENSG00000100354 TNRC6B o+o
ENSG00000198846 TOX +-o
ENSG00000109654 TRIM2 o+o
ENSG00000100505 TRIM9 o++b
ENSG00000196428 TSC22D2 o+-
ENSG00000130338 TULP4 NonAssociatedWithProgression
ENSG00000119048 UBE2B o+-
ENSG00000009335 UBE3C o--a
ENSG00000153560 UBP1 o-+
ENSG00000077254 USP33 o++b
ENSG00000106346 USP42 NonAssociatedWithProgression
ENSG00000140153 WDR20 +oo
ENSG00000047056 WDR37 NonAssociatedWithProgression
ENSG00000198492 YTHDF2 o--a
ENSG00000185728 YTHDF3 o--b
ENSG00000170027 YWHAG o+-
ENSG00000174282 ZBTB4 o-+
ENSG00000058673 ZC3H11A NonAssociatedWithProgression
ENSG00000153786 ZDHHC7 o-o
ENSG00000185650 ZFP36L1 o-o
ENSG00000043355 ZIC2 +-o
ENSG00000010244 ZNF207 NonAssociatedWithProgression
ENSG00000204604 ZNF468 o+o
ENSG00000197619 ZNF615 NonAssociatedWithProgression
ENSG00000197343 ZNF655 o++b
ENSG00000179195 ZNF664 NonAssociatedWithProgression