PEACHi
GeneSet RNA_BINDING (GO_-_Molecular_Function.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-o- -2.7 0.04515 135.0 11.0 4.58
o--a -2.7 0.04505 135.0 31.0 19.17
o--b -3.2 0.03238 135.0 32.0 18.65
DownRegulated -5.9 6.0E-5 135.0 105.0 79.72
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000090861 AARS ---
ENSG00000122729 ACO1 o++a
ENSG00000121057 AKAP1 o--b
ENSG00000214274 ANG o++b
ENSG00000137074 APTX NonAssociatedWithProgression
ENSG00000124788 ATXN1 oo+
ENSG00000148090 AUH NonAssociatedWithProgression
ENSG00000138376 BARD1 o--b
ENSG00000116752 BCAS2 o+o
ENSG00000110619 CARS +oo
ENSG00000099622 CIRBP o--b
ENSG00000071894 CPSF1 o--a
ENSG00000111605 CPSF6 NonAssociatedWithProgression
ENSG00000101138 CSTF1 o++b
ENSG00000101811 CSTF2 o-o
ENSG00000176102 CSTF3 NonAssociatedWithProgression
ENSG00000150316 CWC15 NonAssociatedWithProgression
ENSG00000071626 DAZAP1 ---
ENSG00000100201 DDX17 NonAssociatedWithProgression
ENSG00000157349 DDX19B NonAssociatedWithProgression
ENSG00000174243 DDX23 -o-
ENSG00000100697 DICER1 NonAssociatedWithProgression
ENSG00000130826 DKC1 o--b
ENSG00000144048 DUSP11 o--b
ENSG00000198919 DZIP3 o++a
ENSG00000144895 EIF2A o+-
ENSG00000055332 EIF2AK2 o--a
ENSG00000125977 EIF2S2 NonAssociatedWithProgression
ENSG00000161960 EIF4A1 -o-
ENSG00000141543 EIF4A3 NonAssociatedWithProgression
ENSG00000063046 EIF4B o--a
ENSG00000135930 EIF4E2 o--a
ENSG00000075151 EIF4G3 NonAssociatedWithProgression
ENSG00000106682 EIF4H NonAssociatedWithProgression
ENSG00000132507 EIF5A o--a
ENSG00000120705 ETF1 o--a
ENSG00000182944 EWSR1 o--b
ENSG00000130713 EXOSC2 o--b
ENSG00000075914 EXOSC7 NonAssociatedWithProgression
ENSG00000145982 FARS2 ---
ENSG00000149806 FAU o-o
ENSG00000105202 FBL o-o
ENSG00000102081 FMR1 o+-
ENSG00000089280 FUS o+-
ENSG00000114416 FXR1 ---
ENSG00000082516 GEMIN5 NonAssociatedWithProgression
ENSG00000132463 GRSF1 o--a
ENSG00000186834 HEXIM1 o--a
ENSG00000168517 HEXIM2 NonAssociatedWithProgression
ENSG00000177733 HNRNPA0 NonAssociatedWithProgression
ENSG00000122566 HNRNPA2B1 oo-
ENSG00000104824 HNRNPL NonAssociatedWithProgression
ENSG00000125944 HNRNPR NonAssociatedWithProgression
ENSG00000153187 HNRNPU o--b
ENSG00000152795 HNRPDL oo-
ENSG00000166598 HSP90B1 NonAssociatedWithProgression
ENSG00000073792 IGF2BP2 -oo
ENSG00000136231 IGF2BP3 o-+
ENSG00000143621 ILF2 o-o
ENSG00000129351 ILF3 -o-
ENSG00000136381 IREB2 o--b
ENSG00000152969 JAKMIP1 -+o
ENSG00000121774 KHDRBS1 NonAssociatedWithProgression
ENSG00000088247 KHSRP o--b
ENSG00000151657 KIN o+o
ENSG00000175324 LSM1 o-o
ENSG00000106355 LSM5 o++b
ENSG00000152601 MBNL1 NonAssociatedWithProgression
ENSG00000155438 MKI67IP NonAssociatedWithProgression
ENSG00000183093 MRPL12 ---
ENSG00000214026 MRPL23 ---
ENSG00000114686 MRPL3 NonAssociatedWithProgression
ENSG00000125445 MRPS7 o--b
ENSG00000136937 NCBP1 o+-
ENSG00000115053 NCL o--b
ENSG00000100138 NHP2L1 NonAssociatedWithProgression
ENSG00000140939 NOL3 --o
ENSG00000165271 NOL6 o--b
ENSG00000181163 NPM1 o--b
ENSG00000167005 NUDT21 NonAssociatedWithProgression
ENSG00000083635 NUFIP1 NonAssociatedWithProgression
ENSG00000108256 NUFIP2 --o
ENSG00000070756 PABPC1 o--b
ENSG00000151846 PABPC3 o--b
ENSG00000090621 PABPC4 o--a
ENSG00000100836 PABPN1 o--a
ENSG00000172239 PAIP1 o--b
ENSG00000140694 PARN o-o
ENSG00000169564 PCBP1 NonAssociatedWithProgression
ENSG00000197111 PCBP2 o--a
ENSG00000090097 PCBP4 o-o
ENSG00000105171 POP4 NonAssociatedWithProgression
ENSG00000084072 PPIE o--a
ENSG00000117751 PPP1R8 NonAssociatedWithProgression
ENSG00000117360 PRPF3 o--a
ENSG00000174231 PRPF8 o--b
ENSG00000129084 PSMA1 o--a
ENSG00000011304 PTBP1 ---
ENSG00000146676 PURB o--a
ENSG00000111247 RAD51AP1 NonAssociatedWithProgression
ENSG00000101146 RAE1 -o-
ENSG00000125970 RALY o--a
ENSG00000102317 RBM3 -o-
ENSG00000173933 RBM4 o--a
ENSG00000155636 RBM45 o++b
ENSG00000003756 RBM5 o-o
ENSG00000004534 RBM6 NonAssociatedWithProgression
ENSG00000076067 RBMS2 NonAssociatedWithProgression
ENSG00000171865 RNASEH1 o--b
ENSG00000135828 RNASEL +o+
ENSG00000101654 RNMT NonAssociatedWithProgression
ENSG00000205937 RNPS1 NonAssociatedWithProgression
ENSG00000119314 ROD1 o--b
ENSG00000167526 RPL13 o--b
ENSG00000188846 RPL14 o--a
ENSG00000174748 RPL15 o--a
ENSG00000105640 RPL18A o-o
ENSG00000108298 RPL19 o-o
ENSG00000122026 RPL21 o--a
ENSG00000116251 RPL22 +-o
ENSG00000114391 RPL24 o--b
ENSG00000161970 RPL26 o-o
ENSG00000166441 RPL27A o--a
ENSG00000108107 RPL28 o--b
ENSG00000162244 RPL29 o--a
ENSG00000100316 RPL3 -o-
ENSG00000156482 RPL30 o++b
ENSG00000071082 RPL31 o-+
ENSG00000109475 RPL34 NonAssociatedWithProgression
ENSG00000136942 RPL35 o--b
ENSG00000198918 RPL39 o-+
ENSG00000174444 RPL4 o--b
ENSG00000089009 RPL6 o--b
ENSG00000147604 RPL7 NonAssociatedWithProgression
ENSG00000148303 RPL7A -o-
ENSG00000163682 RPL9 NonAssociatedWithProgression
ENSG00000089157 RPLP0 o--b
ENSG00000137818 RPLP1 NonAssociatedWithProgression
ENSG00000177600 RPLP2 NonAssociatedWithProgression
ENSG00000124614 RPS10 NonAssociatedWithProgression
ENSG00000112306 RPS12 o--a
ENSG00000110700 RPS13 NonAssociatedWithProgression
ENSG00000164587 RPS14 -o-
ENSG00000134419 RPS15A o+-
ENSG00000105372 RPS19 -o-
ENSG00000140988 RPS2 o--a
ENSG00000008988 RPS20 o--a
ENSG00000186468 RPS23 o-o
ENSG00000138326 RPS24 NonAssociatedWithProgression
ENSG00000197728 RPS26 NonAssociatedWithProgression
ENSG00000177954 RPS27 o-o
ENSG00000213741 RPS29 NonAssociatedWithProgression
ENSG00000149273 RPS3 o--b
ENSG00000145425 RPS3A o-o
ENSG00000083845 RPS5 o--a
ENSG00000137154 RPS6 o--a
ENSG00000171863 RPS7 o--a
ENSG00000142937 RPS8 NonAssociatedWithProgression
ENSG00000137996 RTCD1 NonAssociatedWithProgression
ENSG00000031698 SARS NonAssociatedWithProgression
ENSG00000109618 SEPSECS o-o
ENSG00000142864 SERBP1 o+-
ENSG00000168066 SF1 o-o
ENSG00000183431 SF3A3 NonAssociatedWithProgression
ENSG00000189091 SF3B3 NonAssociatedWithProgression
ENSG00000143368 SF3B4 o--b
ENSG00000092208 SIP1 NonAssociatedWithProgression
ENSG00000163950 SLBP NonAssociatedWithProgression
ENSG00000164609 SLU7 o--a
ENSG00000119953 SMNDC1 +oo
ENSG00000167088 SNRPD1 o--a
ENSG00000140319 SRP14 NonAssociatedWithProgression
ENSG00000133226 SRRM1 o--b
ENSG00000138385 SSB NonAssociatedWithProgression
ENSG00000124214 STAU1 NonAssociatedWithProgression
ENSG00000040341 STAU2 -oo
ENSG00000156502 SUPV3L1 o--a
ENSG00000148296 SURF6 NonAssociatedWithProgression
ENSG00000135316 SYNCRIP o--b
ENSG00000059588 TARBP1 -+o
ENSG00000139546 TARBP2 o-o
ENSG00000129566 TEP1 +o+
ENSG00000116001 TIA1 -o-
ENSG00000151923 TIAL1 o+o
ENSG00000072756 TRNT1 o++a
ENSG00000116747 TROVE2 NonAssociatedWithProgression
ENSG00000141759 TXNL4A NonAssociatedWithProgression
ENSG00000184575 XPOT NonAssociatedWithProgression
ENSG00000128016 ZFP36 o--b
ENSG00000185650 ZFP36L1 o-o
ENSG00000113761 ZNF346 -o-
ENSG00000075292 ZNF638 o+o
ENSG00000132485 ZRANB2 o-+