PEACHi
GeneSet POSITIVE_REGULATION_OF_CELLULAR_PROCESS (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -2.9 0.02885 250.0 170.0 147.63
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000165029 ABCA1 --o
ENSG00000097007 ABL1 o--a
ENSG00000100813 ACIN1 ---
ENSG00000114739 ACVR2B +-o
ENSG00000169129 AFAP1L2 NonAssociatedWithProgression
ENSG00000164252 AGGF1 +o+
ENSG00000156709 AIFM1 NonAssociatedWithProgression
ENSG00000166971 AKTIP NonAssociatedWithProgression
ENSG00000126016 AMOT NonAssociatedWithProgression
ENSG00000214274 ANG o++b
ENSG00000165527 ARF6 NonAssociatedWithProgression
ENSG00000132694 ARHGEF11 -+o
ENSG00000117713 ARID1A o--b
ENSG00000133794 ARNTL NonAssociatedWithProgression
ENSG00000128272 ATF4 o--b
ENSG00000118217 ATF6 o--a
ENSG00000171681 ATF7IP ---
ENSG00000197548 ATG7 ---
ENSG00000017260 ATP2C1 oo-
ENSG00000175756 AURKAIP1 ---
ENSG00000030110 BAK1 o--b
ENSG00000138376 BARD1 o--b
ENSG00000105327 BBC3 +oo
ENSG00000142867 BCL10 o+o
ENSG00000153094 BCL2L11 NonAssociatedWithProgression
ENSG00000069399 BCL3 NonAssociatedWithProgression
ENSG00000113916 BCL6 +-o
ENSG00000029363 BCLAF1 NonAssociatedWithProgression
ENSG00000015475 BID -oo
ENSG00000100290 BIK o--a
ENSG00000110330 BIRC2 NonAssociatedWithProgression
ENSG00000089685 BIRC5 ---
ENSG00000168283 BMI1 NonAssociatedWithProgression
ENSG00000125378 BMP4 +-o
ENSG00000113734 BNIP1 o--b
ENSG00000104765 BNIP3L NonAssociatedWithProgression
ENSG00000171634 BPTF NonAssociatedWithProgression
ENSG00000012048 BRCA1 NonAssociatedWithProgression
ENSG00000133639 BTG1 NonAssociatedWithProgression
ENSG00000089486 C16orf5 o--b
ENSG00000110931 CAMKK2 NonAssociatedWithProgression
ENSG00000171302 CANT1 o--b
ENSG00000014216 CAPN1 ---
ENSG00000126247 CAPNS1 o++a
ENSG00000164305 CASP3 o++b
ENSG00000196954 CASP4 o++a
ENSG00000138794 CASP6 o++b
ENSG00000064012 CASP8 +-o
ENSG00000110395 CBL o--b
ENSG00000132024 CC2D1A NonAssociatedWithProgression
ENSG00000112576 CCND3 o--b
ENSG00000134480 CCNH -o-
ENSG00000116824 CD2 ---
ENSG00000139193 CD27 NonAssociatedWithProgression
ENSG00000178562 CD28 o+o
ENSG00000004468 CD38 -+o
ENSG00000198851 CD3E o--a
ENSG00000196776 CD47 NonAssociatedWithProgression
ENSG00000125726 CD70 NonAssociatedWithProgression
ENSG00000110651 CD81 o--b
ENSG00000151465 CDC123 NonAssociatedWithProgression
ENSG00000101224 CDC25B o--a
ENSG00000070831 CDC42 +oo
ENSG00000097046 CDC7 NonAssociatedWithProgression
ENSG00000123374 CDK2 oo-
ENSG00000135446 CDK4 o--a
ENSG00000164885 CDK5 ---
ENSG00000176749 CDK5R1 NonAssociatedWithProgression
ENSG00000105810 CDK6 o--a
ENSG00000134058 CDK7 o+o
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000168564 CDKN2AIP NonAssociatedWithProgression
ENSG00000123080 CDKN2C o-o
ENSG00000003402 CFLAR +-o
ENSG00000183765 CHEK2 ---
ENSG00000144021 CIAO1 -+o
ENSG00000187288 CIDEC NonAssociatedWithProgression
ENSG00000164442 CITED2 o++b
ENSG00000128973 CLN6 ---
ENSG00000169372 CRADD o++b
ENSG00000146592 CREB5 +oo
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000102974 CTCF o--b
ENSG00000055130 CUL1 o++a
ENSG00000108094 CUL2 o+o
ENSG00000036257 CUL3 o--a
ENSG00000139842 CUL4A oo-
ENSG00000166266 CUL5 o--b
ENSG00000171604 CXXC5 o+-
ENSG00000112977 DAP NonAssociatedWithProgression
ENSG00000132676 DAP3 o--a
ENSG00000196730 DAPK1 o++a
ENSG00000204209 DAXX o--b
ENSG00000013573 DDX11 o--a
ENSG00000158796 DEDD -o-
ENSG00000160570 DEDD2 o--a
ENSG00000072849 DERL2 o-o
ENSG00000095059 DHPS o-o
ENSG00000184047 DIABLO o--a
ENSG00000069345 DNAJA2 o-o
ENSG00000011332 DPF1 o--a
ENSG00000133884 DPF2 o-o
ENSG00000127334 DYRK2 o--b
ENSG00000114346 ECT2 NonAssociatedWithProgression
ENSG00000104529 EEF1D o--a
ENSG00000124802 EEF1E1 NonAssociatedWithProgression
ENSG00000120738 EGR1 NonAssociatedWithProgression
ENSG00000149547 EI24 ---
ENSG00000145191 EIF2B5 ---
ENSG00000132507 EIF5A o--a
ENSG00000120690 ELF1 o--b
ENSG00000126767 ELK1 ---
ENSG00000120616 EPC1 o--b
ENSG00000104884 ERCC2 ---
ENSG00000163161 ERCC3 o-o
ENSG00000134954 ETS1 NonAssociatedWithProgression
ENSG00000168040 FADD o--b
ENSG00000185104 FAF1 o--a
ENSG00000026103 FAS NonAssociatedWithProgression
ENSG00000164896 FASTK o--a
ENSG00000213066 FGFR1OP o+-
ENSG00000088832 FKBP1A ---
ENSG00000196924 FLNA ---
ENSG00000090554 FLT3LG +o+
ENSG00000037280 FLT4 NonAssociatedWithProgression
ENSG00000118689 FOXO3 NonAssociatedWithProgression
ENSG00000126603 GLIS2 NonAssociatedWithProgression
ENSG00000111711 GOLT1B o-o
ENSG00000117262 GPR89A NonAssociatedWithProgression
ENSG00000082701 GSK3B -o-
ENSG00000110768 GTF2H1 o++b
ENSG00000172534 HCFC1 o--b
ENSG00000180353 HCLS1 o--a
ENSG00000100644 HIF1A NonAssociatedWithProgression
ENSG00000064393 HIPK2 NonAssociatedWithProgression
ENSG00000127124 HIVEP3 +-o
ENSG00000137309 HMGA1 o--b
ENSG00000165704 HPRT1 NonAssociatedWithProgression
ENSG00000080824 HSP90AA1 NonAssociatedWithProgression
ENSG00000096384 HSP90AB1 o--b
ENSG00000109854 HTATIP2 o+-
ENSG00000163565 IFI16 o--a
ENSG00000140443 IGF1R o++b
ENSG00000143466 IKBKE ---
ENSG00000073009 IKBKG --o
ENSG00000113520 IL4 NonAssociatedWithProgression
ENSG00000143621 ILF2 o-o
ENSG00000129351 ILF3 -o-
ENSG00000152409 JMY o--a
ENSG00000140854 KATNB1 o--b
ENSG00000182866 LCK o-o
ENSG00000189067 LITAF o++a
ENSG00000162337 LRP5 NonAssociatedWithProgression
ENSG00000226979 LTA NonAssociatedWithProgression
ENSG00000227507 LTB -o-
ENSG00000172175 MALT1 +o+
ENSG00000161021 MAML1 o--b
ENSG00000034152 MAP2K3 ---
ENSG00000130758 MAP3K10 o--a
ENSG00000198909 MAP3K3 o-+
ENSG00000197442 MAP3K5 o++a
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000186868 MAPT o++a
ENSG00000007047 MARK4 ---
ENSG00000232119 MCTS1 -+o
ENSG00000125686 MED1 NonAssociatedWithProgression
ENSG00000108510 MED13 NonAssociatedWithProgression
ENSG00000180182 MED14 -oo
ENSG00000152944 MED21 -o-
ENSG00000133997 MED6 NonAssociatedWithProgression
ENSG00000154305 MIA3 NonAssociatedWithProgression
ENSG00000197530 MIB2 ---
ENSG00000198160 MIER1 o--a
ENSG00000186260 MKL2 +o+
ENSG00000155229 MMS19 o--b
ENSG00000183093 MRPL12 ---
ENSG00000137409 MTCH1 NonAssociatedWithProgression
ENSG00000136997 MYC o--b
ENSG00000172936 MYD88 +o+
ENSG00000103510 MYST1 o--b
ENSG00000083168 MYST3 +-o
ENSG00000156650 MYST4 NonAssociatedWithProgression
ENSG00000187109 NAP1L1 +-o
ENSG00000136937 NCBP1 o+-
ENSG00000114503 NCBP2 o--b
ENSG00000158092 NCK1 o+-
ENSG00000071051 NCK2 o--b
ENSG00000198646 NCOA6 o--b
ENSG00000131507 NDFIP1 +-o
ENSG00000102471 NDFIP2 NonAssociatedWithProgression
ENSG00000186010 NDUFA13 o-o
ENSG00000213619 NDUFS3 NonAssociatedWithProgression
ENSG00000164258 NDUFS4 NonAssociatedWithProgression
ENSG00000196712 NF1 o+o
ENSG00000186575 NF2 o--b
ENSG00000239672 NME1 o--a
ENSG00000011052 NME2 NonAssociatedWithProgression
ENSG00000106100 NOD1 o-+
ENSG00000198000 NOL8 -oo
ENSG00000134250 NOTCH2 o-o
ENSG00000170485 NPAS2 o-+
ENSG00000156642 NPTN +o+
ENSG00000180530 NRIP1 o++a
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000164978 NUDT2 o-+
ENSG00000083635 NUFIP1 NonAssociatedWithProgression
ENSG00000213024 NUP62 o--a
ENSG00000137804 NUSAP1 NonAssociatedWithProgression
ENSG00000182500 ORAI1 NonAssociatedWithProgression
ENSG00000132570 PCBD2 -oo
ENSG00000090097 PCBP4 o-o
ENSG00000105185 PDCD5 o-o
ENSG00000249915 PDCD6 NonAssociatedWithProgression
ENSG00000090470 PDCD7 NonAssociatedWithProgression
ENSG00000100410 PHF5A o--b
ENSG00000118495 PLAGL1 NonAssociatedWithProgression
ENSG00000122194 PLG o+o
ENSG00000141682 PMAIP1 oo-
ENSG00000140464 PML o-o
ENSG00000186951 PPARA o++a
ENSG00000155846 PPARGC1B NonAssociatedWithProgression
ENSG00000100614 PPM1A o--a
ENSG00000113575 PPP2CA o--b
ENSG00000105568 PPP2R1A o--b
ENSG00000119383 PPP2R4 ---
ENSG00000011485 PPP5C o--a
ENSG00000131238 PPT1 +-o
ENSG00000154229 PRKCA oo+
ENSG00000101161 PRPF6 o-o
ENSG00000106772 PRUNE2 o++a
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000120899 PTK2B NonAssociatedWithProgression
ENSG00000081237 PTPRC o+o
ENSG00000103490 PYCARD o--a
ENSG00000136238 RAC1 NonAssociatedWithProgression
ENSG00000051180 RAD51 NonAssociatedWithProgression
ENSG00000239306 RBM14 o--a
ENSG00000162924 REL o-o
ENSG00000173039 RELA o--a
ENSG00000174136 RGMB o++b
ENSG00000067560 RHOA o-o
ENSG00000155366 RHOC --o
ENSG00000177105 RHOG o--a
ENSG00000137275 RIPK1 o--b
ENSG00000104312 RIPK2 o++b
ENSG00000114125 RNF7 o+o
ENSG00000198963 RORB NonAssociatedWithProgression
ENSG00000215472 RPL17 o-o
ENSG00000105372 RPS19 -o-
ENSG00000145425 RPS3A o-o
ENSG00000155876 RRAGA oo-
ENSG00000048649 RSF1 +-o
ENSG00000159216 RUNX1 o--b
ENSG00000020633 RUNX3 o--b
ENSG00000186350 RXRA ---
ENSG00000161526 SAP30BP o--b
ENSG00000114650 SCAP ---
ENSG00000132386 SERPINF1 ---
ENSG00000197019 SERTAD1 ---
ENSG00000184990 SIVA1 o--a
ENSG00000144136 SLC20A1 o-o
ENSG00000157593 SLC35B2 o-o
ENSG00000129353 SLC44A2 NonAssociatedWithProgression
ENSG00000175387 SMAD2 NonAssociatedWithProgression
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000173473 SMARCC1 o--a
ENSG00000139613 SMARCC2 --o
ENSG00000066117 SMARCD1 NonAssociatedWithProgression
ENSG00000082014 SMARCD3 +oo
ENSG00000119953 SMNDC1 +oo
ENSG00000171150 SOCS5 oo-
ENSG00000185591 SP1 o--a
ENSG00000197471 SPN o--a
ENSG00000161011 SQSTM1 ---
ENSG00000124783 SSR1 -+o
ENSG00000124356 STAMBP o--b
ENSG00000164543 STK17A NonAssociatedWithProgression
ENSG00000081320 STK17B NonAssociatedWithProgression
ENSG00000104375 STK3 oo+
ENSG00000101109 STK4 NonAssociatedWithProgression
ENSG00000103266 STUB1 ---
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000137413 TAF8 NonAssociatedWithProgression
ENSG00000149930 TAOK2 NonAssociatedWithProgression
ENSG00000135090 TAOK3 o+o
ENSG00000183735 TBK1 o++b
ENSG00000136270 TBRG4 o--a
ENSG00000114354 TFG NonAssociatedWithProgression
ENSG00000105329 TGFB1 o--a
ENSG00000163513 TGFBR2 +o+
ENSG00000054118 THRAP3 o--a
ENSG00000116001 TIA1 -o-
ENSG00000151923 TIAL1 o+o
ENSG00000127666 TICAM1 o--b
ENSG00000102265 TIMP1 o--a
ENSG00000075131 TIPIN NonAssociatedWithProgression
ENSG00000158604 TMED4 +o+
ENSG00000091947 TMEM101 oo+
ENSG00000175348 TMEM9B NonAssociatedWithProgression
ENSG00000120889 TNFRSF10B o+o
ENSG00000067182 TNFRSF1A NonAssociatedWithProgression
ENSG00000117586 TNFSF4 o++a
ENSG00000061938 TNK2 o-o
ENSG00000131747 TOP2A o--b
ENSG00000141510 TP53 o--a
ENSG00000143514 TP53BP2 oo-
ENSG00000166340 TPP1 o--a
ENSG00000102871 TRADD NonAssociatedWithProgression
ENSG00000131323 TRAF3 -+o
ENSG00000056972 TRAF3IP2 o+o
ENSG00000175104 TRAF6 NonAssociatedWithProgression
ENSG00000183763 TRAIP NonAssociatedWithProgression
ENSG00000163519 TRAT1 NonAssociatedWithProgression
ENSG00000124496 TRERF1 --o
ENSG00000204977 TRIM13 o-o
ENSG00000130726 TRIM28 o--a
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000165409 TSHR -o-
ENSG00000112742 TTK o--b
ENSG00000170315 UBB ---
ENSG00000175063 UBE2C o-o
ENSG00000072401 UBE2D1 NonAssociatedWithProgression
ENSG00000177889 UBE2N o--a
ENSG00000244687 UBE2V1 oo-
ENSG00000183520 UTP11L NonAssociatedWithProgression
ENSG00000101558 VAPA NonAssociatedWithProgression
ENSG00000112715 VEGFA +-o
ENSG00000173511 VEGFB o--b
ENSG00000196419 XRCC6 o--b
ENSG00000015153 YAF2 -oo
ENSG00000128245 YWHAH +-o
ENSG00000115085 ZAP70 o--b
ENSG00000177054 ZDHHC13 NonAssociatedWithProgression
ENSG00000186908 ZDHHC17 o-+
ENSG00000122515 ZMIZ2 o--b
ENSG00000102935 ZNF423 o--b
ENSG00000180855 ZNF443 o++b