PEACHi
GeneSet POSITIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -3.3 0.01441 88.0 66.0 51.97
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000165029 ABCA1 --o
ENSG00000169129 AFAP1L2 NonAssociatedWithProgression
ENSG00000166971 AKTIP NonAssociatedWithProgression
ENSG00000214274 ANG o++b
ENSG00000165527 ARF6 NonAssociatedWithProgression
ENSG00000132694 ARHGEF11 -+o
ENSG00000117713 ARID1A o--b
ENSG00000133794 ARNTL NonAssociatedWithProgression
ENSG00000128272 ATF4 o--b
ENSG00000118217 ATF6 o--a
ENSG00000171681 ATF7IP ---
ENSG00000197548 ATG7 ---
ENSG00000175756 AURKAIP1 ---
ENSG00000142867 BCL10 o+o
ENSG00000069399 BCL3 NonAssociatedWithProgression
ENSG00000125378 BMP4 +-o
ENSG00000171634 BPTF NonAssociatedWithProgression
ENSG00000012048 BRCA1 NonAssociatedWithProgression
ENSG00000110931 CAMKK2 NonAssociatedWithProgression
ENSG00000112576 CCND3 o--b
ENSG00000134480 CCNH -o-
ENSG00000178562 CD28 o+o
ENSG00000110651 CD81 o--b
ENSG00000134058 CDK7 o+o
ENSG00000164442 CITED2 o++b
ENSG00000128973 CLN6 ---
ENSG00000146592 CREB5 +oo
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000102974 CTCF o--b
ENSG00000127334 DYRK2 o--b
ENSG00000120738 EGR1 NonAssociatedWithProgression
ENSG00000145191 EIF2B5 ---
ENSG00000132507 EIF5A o--a
ENSG00000120690 ELF1 o--b
ENSG00000126767 ELK1 ---
ENSG00000120616 EPC1 o--b
ENSG00000104884 ERCC2 ---
ENSG00000163161 ERCC3 o-o
ENSG00000118689 FOXO3 NonAssociatedWithProgression
ENSG00000126603 GLIS2 NonAssociatedWithProgression
ENSG00000110768 GTF2H1 o++b
ENSG00000180353 HCLS1 o--a
ENSG00000100644 HIF1A NonAssociatedWithProgression
ENSG00000127124 HIVEP3 +-o
ENSG00000137309 HMGA1 o--b
ENSG00000165704 HPRT1 NonAssociatedWithProgression
ENSG00000080824 HSP90AA1 NonAssociatedWithProgression
ENSG00000096384 HSP90AB1 o--b
ENSG00000113520 IL4 NonAssociatedWithProgression
ENSG00000143621 ILF2 o-o
ENSG00000129351 ILF3 -o-
ENSG00000140854 KATNB1 o--b
ENSG00000227507 LTB -o-
ENSG00000161021 MAML1 o--b
ENSG00000034152 MAP2K3 ---
ENSG00000186868 MAPT o++a
ENSG00000125686 MED1 NonAssociatedWithProgression
ENSG00000108510 MED13 NonAssociatedWithProgression
ENSG00000180182 MED14 -oo
ENSG00000152944 MED21 -o-
ENSG00000133997 MED6 NonAssociatedWithProgression
ENSG00000186260 MKL2 +o+
ENSG00000155229 MMS19 o--b
ENSG00000183093 MRPL12 ---
ENSG00000103510 MYST1 o--b
ENSG00000083168 MYST3 +-o
ENSG00000156650 MYST4 NonAssociatedWithProgression
ENSG00000136937 NCBP1 o+-
ENSG00000158092 NCK1 o+-
ENSG00000071051 NCK2 o--b
ENSG00000198646 NCOA6 o--b
ENSG00000170485 NPAS2 o-+
ENSG00000180530 NRIP1 o++a
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000083635 NUFIP1 NonAssociatedWithProgression
ENSG00000213024 NUP62 o--a
ENSG00000132570 PCBD2 -oo
ENSG00000100410 PHF5A o--b
ENSG00000118495 PLAGL1 NonAssociatedWithProgression
ENSG00000186951 PPARA o++a
ENSG00000155846 PPARGC1B NonAssociatedWithProgression
ENSG00000119383 PPP2R4 ---
ENSG00000101161 PRPF6 o-o
ENSG00000051180 RAD51 NonAssociatedWithProgression
ENSG00000239306 RBM14 o--a
ENSG00000174136 RGMB o++b
ENSG00000198963 RORB NonAssociatedWithProgression
ENSG00000048649 RSF1 +-o
ENSG00000159216 RUNX1 o--b
ENSG00000186350 RXRA ---
ENSG00000114650 SCAP ---
ENSG00000175387 SMAD2 NonAssociatedWithProgression
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000173473 SMARCC1 o--a
ENSG00000139613 SMARCC2 --o
ENSG00000066117 SMARCD1 NonAssociatedWithProgression
ENSG00000082014 SMARCD3 +oo
ENSG00000185591 SP1 o--a
ENSG00000197471 SPN o--a
ENSG00000161011 SQSTM1 ---
ENSG00000103266 STUB1 ---
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000137413 TAF8 NonAssociatedWithProgression
ENSG00000105329 TGFB1 o--a
ENSG00000054118 THRAP3 o--a
ENSG00000067182 TNFRSF1A NonAssociatedWithProgression
ENSG00000061938 TNK2 o-o
ENSG00000141510 TP53 o--a
ENSG00000166340 TPP1 o--a
ENSG00000124496 TRERF1 --o
ENSG00000130726 TRIM28 o--a
ENSG00000170315 UBB ---
ENSG00000072401 UBE2D1 NonAssociatedWithProgression
ENSG00000177889 UBE2N o--a
ENSG00000196419 XRCC6 o--b
ENSG00000015153 YAF2 -oo
ENSG00000128245 YWHAH +-o
ENSG00000122515 ZMIZ2 o--b
ENSG00000102935 ZNF423 o--b