PEACHi
GeneSet ORGANELLE_ORGANIZATION_AND_BIOGENESIS (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -3.3 0.03669 241.0 51.0 33.3
DownRegulated -3.1 0.02102 241.0 165.0 142.32
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000165029 ABCA1 --o
ENSG00000117528 ABCD3 NonAssociatedWithProgression
ENSG00000138443 ABI2 o-o
ENSG00000097007 ABL1 o--a
ENSG00000102977 ACD o+-
ENSG00000100813 ACIN1 ---
ENSG00000136518 ACTL6A o--a
ENSG00000156709 AIFM1 NonAssociatedWithProgression
ENSG00000126016 AMOT NonAssociatedWithProgression
ENSG00000214274 ANG o++b
ENSG00000011426 ANLN NonAssociatedWithProgression
ENSG00000042753 AP2S1 o--b
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000165527 ARF6 NonAssociatedWithProgression
ENSG00000132254 ARFIP2 ---
ENSG00000089820 ARHGAP4 ---
ENSG00000111348 ARHGDIB o--b
ENSG00000116584 ARHGEF2 o--b
ENSG00000117713 ARID1A o--b
ENSG00000241685 ARPC1A o+o
ENSG00000241553 ARPC4 o--b
ENSG00000162704 ARPC5 o--b
ENSG00000113273 ARSB -+o
ENSG00000111875 ASF1A NonAssociatedWithProgression
ENSG00000101844 ATG4A o++a
ENSG00000168397 ATG4B o--b
ENSG00000125703 ATG4C o++b
ENSG00000130734 ATG4D o--b
ENSG00000198925 ATG9A o--a
ENSG00000017260 ATP2C1 oo-
ENSG00000163635 ATXN7 NonAssociatedWithProgression
ENSG00000030110 BAK1 o--b
ENSG00000105327 BBC3 +oo
ENSG00000140463 BBS4 o--b
ENSG00000171791 BCL2 NonAssociatedWithProgression
ENSG00000171552 BCL2L1 ---
ENSG00000015475 BID -oo
ENSG00000113734 BNIP1 o--b
ENSG00000171634 BPTF NonAssociatedWithProgression
ENSG00000144559 C3orf31 NonAssociatedWithProgression
ENSG00000164305 CASP3 o++b
ENSG00000115355 CCDC88A +o+
ENSG00000094880 CDC23 NonAssociatedWithProgression
ENSG00000070831 CDC42 +oo
ENSG00000143776 CDC42BPA NonAssociatedWithProgression
ENSG00000146670 CDCA5 o--b
ENSG00000138778 CENPE NonAssociatedWithProgression
ENSG00000153044 CENPH oo-
ENSG00000151849 CENPJ o+o
ENSG00000126001 CEP250 o-o
ENSG00000153140 CETN3 oo+
ENSG00000172757 CFL1 o-o
ENSG00000167670 CHAF1A o--b
ENSG00000159259 CHAF1B o-o
ENSG00000131165 CHMP1A o--a
ENSG00000175216 CKAP5 NonAssociatedWithProgression
ENSG00000074054 CLASP1 NonAssociatedWithProgression
ENSG00000163539 CLASP2 +oo
ENSG00000188603 CLN3 o++b
ENSG00000102805 CLN5 NonAssociatedWithProgression
ENSG00000128973 CLN6 ---
ENSG00000064666 CNN2 o--b
ENSG00000170037 CNTROB o-o
ENSG00000135775 COG2 o--a
ENSG00000163626 COX18 o--b
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000179979 CRIPAK NonAssociatedWithProgression
ENSG00000167193 CRK o+o
ENSG00000058453 CROCC --o
ENSG00000172115 CYCS o--b
ENSG00000113758 DBN1 NonAssociatedWithProgression
ENSG00000013573 DDX11 o--a
ENSG00000160570 DEDD2 o--a
ENSG00000160049 DFFA NonAssociatedWithProgression
ENSG00000083520 DIS3 o--a
ENSG00000130826 DKC1 o--b
ENSG00000075711 DLG1 NonAssociatedWithProgression
ENSG00000105993 DNAJB6 o+-
ENSG00000087470 DNM1L NonAssociatedWithProgression
ENSG00000134516 DOCK2 o--a
ENSG00000083097 DOPEY1 o-+
ENSG00000151914 DST -+o
ENSG00000125868 DSTN -+o
ENSG00000047579 DTNBP1 o-o
ENSG00000158560 DYNC1I1 o++a
ENSG00000088986 DYNLL1 --o
ENSG00000181090 EHMT1 NonAssociatedWithProgression
ENSG00000144895 EIF2A o+-
ENSG00000155849 ELMO1 o+o
ENSG00000085832 EPS15 +-o
ENSG00000175595 ERCC4 o-o
ENSG00000135476 ESPL1 o-+
ENSG00000196405 EVL NonAssociatedWithProgression
ENSG00000130713 EXOSC2 o--b
ENSG00000107371 EXOSC3 NonAssociatedWithProgression
ENSG00000075914 EXOSC7 NonAssociatedWithProgression
ENSG00000106462 EZH2 NonAssociatedWithProgression
ENSG00000092820 EZR NonAssociatedWithProgression
ENSG00000105202 FBL o-o
ENSG00000102302 FGD1 NonAssociatedWithProgression
ENSG00000146192 FGD2 -+o
ENSG00000127084 FGD3 o--a
ENSG00000180263 FGD6 o++b
ENSG00000214253 FIS1 --o
ENSG00000196924 FLNA ---
ENSG00000136068 FLNB NonAssociatedWithProgression
ENSG00000171298 GAA o--a
ENSG00000066455 GOLGA5 -+o
ENSG00000173230 GOLGB1 o--b
ENSG00000233276 GPX1 ---
ENSG00000116478 HDAC1 ---
ENSG00000100429 HDAC10 o--b
ENSG00000163517 HDAC11 -oo
ENSG00000196591 HDAC2 NonAssociatedWithProgression
ENSG00000171720 HDAC3 ---
ENSG00000068024 HDAC4 o--b
ENSG00000094631 HDAC6 o--a
ENSG00000147099 HDAC8 oo-
ENSG00000119969 HELLS +o+
ENSG00000149929 HIRIP3 o--a
ENSG00000137309 HMGA1 o--b
ENSG00000149948 HMGA2 oo-
ENSG00000189403 HMGB1 o--b
ENSG00000168172 HOOK3 o--b
ENSG00000107521 HPS1 NonAssociatedWithProgression
ENSG00000100099 HPS4 NonAssociatedWithProgression
ENSG00000080824 HSP90AA1 NonAssociatedWithProgression
ENSG00000086758 HUWE1 o-o
ENSG00000126709 IFI6 oo+
ENSG00000140854 KATNB1 o--b
ENSG00000138160 KIF11 o+-
ENSG00000197892 KIF13B +o+
ENSG00000054523 KIF1B o++a
ENSG00000137807 KIF23 o--a
ENSG00000142945 KIF2C o--b
ENSG00000131437 KIF3A oo-
ENSG00000101350 KIF3B o--a
ENSG00000090889 KIF4A NonAssociatedWithProgression
ENSG00000170759 KIF5B NonAssociatedWithProgression
ENSG00000168280 KIF5C +o+
ENSG00000075945 KIFAP3 NonAssociatedWithProgression
ENSG00000076321 KLHL20 o++b
ENSG00000182481 KPNA2 o--a
ENSG00000118162 KPTN ---
ENSG00000002834 LASP1 o--b
ENSG00000050405 LIMA1 -+o
ENSG00000131899 LLGL1 o--a
ENSG00000118308 LRMP o--a
ENSG00000138095 LRPPRC NonAssociatedWithProgression
ENSG00000130479 MAP1S o--a
ENSG00000173327 MAP3K11 ---
ENSG00000101367 MAPRE1 o--b
ENSG00000186868 MAPT o++a
ENSG00000007047 MARK4 ---
ENSG00000116688 MFN2 o--b
ENSG00000027001 MIPEP -oo
ENSG00000167842 MIS12 o+o
ENSG00000165943 MOAP1 NonAssociatedWithProgression
ENSG00000115204 MPV17 --o
ENSG00000183093 MRPL12 ---
ENSG00000095002 MSH2 +oo
ENSG00000125459 MSTO1 NonAssociatedWithProgression
ENSG00000149480 MTA2 ---
ENSG00000127989 MTERF o--a
ENSG00000128654 MTX2 o++b
ENSG00000133026 MYH10 o--a
ENSG00000100345 MYH9 -o-
ENSG00000092841 MYL6 o-o
ENSG00000099331 MYO9B oo+
ENSG00000103510 MYST1 o--b
ENSG00000083168 MYST3 +-o
ENSG00000156650 MYST4 NonAssociatedWithProgression
ENSG00000103174 NAGPA NonAssociatedWithProgression
ENSG00000187109 NAP1L1 +-o
ENSG00000205531 NAP1L4 ---
ENSG00000132780 NASP o--a
ENSG00000104320 NBN NonAssociatedWithProgression
ENSG00000121152 NCAPH o--a
ENSG00000158092 NCK1 o+-
ENSG00000071051 NCK2 o--b
ENSG00000080986 NDC80 o++b
ENSG00000072864 NDE1 --o
ENSG00000186010 NDUFA13 o-o
ENSG00000164258 NDUFS4 NonAssociatedWithProgression
ENSG00000168653 NDUFS5 o--a
ENSG00000115286 NDUFS7 ---
ENSG00000110717 NDUFS8 o--a
ENSG00000196712 NF1 o+o
ENSG00000186575 NF2 o--b
ENSG00000166197 NOLC1 o--b
ENSG00000182446 NPLOC4 o--a
ENSG00000181163 NPM1 o--b
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000103274 NUBP1 o--b
ENSG00000137497 NUMA1 o--b
ENSG00000137804 NUSAP1 NonAssociatedWithProgression
ENSG00000198836 OPA1 o-+
ENSG00000123240 OPTN +o+
ENSG00000100266 PACSIN2 NonAssociatedWithProgression
ENSG00000007168 PAFAH1B1 o+-
ENSG00000149269 PAK1 oo+
ENSG00000145730 PAM oo+
ENSG00000163939 PBRM1 NonAssociatedWithProgression
ENSG00000140992 PDPK1 -o-
ENSG00000083642 PDS5B NonAssociatedWithProgression
ENSG00000127980 PEX1 +-o
ENSG00000157911 PEX10 ---
ENSG00000108733 PEX12 o++b
ENSG00000162928 PEX13 o+o
ENSG00000142655 PEX14 o++b
ENSG00000162735 PEX19 --o
ENSG00000034693 PEX3 NonAssociatedWithProgression
ENSG00000167085 PHB NonAssociatedWithProgression
ENSG00000140451 PIF1 ---
ENSG00000141682 PMAIP1 oo-
ENSG00000140464 PML o-o
ENSG00000105171 POP4 NonAssociatedWithProgression
ENSG00000128513 POT1 o++b
ENSG00000131238 PPT1 +-o
ENSG00000198901 PRC1 +-o
ENSG00000132600 PRMT7 o--a
ENSG00000110958 PTGES3 o--b
ENSG00000124209 RAB22A o+-
ENSG00000136238 RAC1 NonAssociatedWithProgression
ENSG00000169750 RAC3 ---
ENSG00000161800 RACGAP1 o-+
ENSG00000113522 RAD50 NonAssociatedWithProgression
ENSG00000132341 RAN o--b
ENSG00000145715 RASA1 NonAssociatedWithProgression
ENSG00000162521 RBBP4 NonAssociatedWithProgression
ENSG00000239306 RBM14 o--a
ENSG00000180198 RCC1 o--a
ENSG00000035928 RFC1 o--b
ENSG00000067560 RHOA o-o
ENSG00000139725 RHOF --o
ENSG00000126858 RHOT1 NonAssociatedWithProgression
ENSG00000140983 RHOT2 o--b
ENSG00000164327 RICTOR o--b
ENSG00000172602 RND1 -o-
ENSG00000034677 RNF19A o-o
ENSG00000067900 ROCK1 o+o
ENSG00000164587 RPS14 -o-
ENSG00000100784 RPS6KA5 NonAssociatedWithProgression
ENSG00000048649 RSF1 +-o
ENSG00000168061 SAC3D1 NonAssociatedWithProgression
ENSG00000160633 SAFB o--b
ENSG00000156876 SASS6 o++b
ENSG00000182568 SATB1 o--a
ENSG00000198301 SDAD1 o--a
ENSG00000107651 SEC23IP NonAssociatedWithProgression
ENSG00000184702 SEPT5 NonAssociatedWithProgression
ENSG00000119335 SET o--b
ENSG00000164403 SHROOM1 --o
ENSG00000146950 SHROOM2 o++b
ENSG00000096717 SIRT1 +-o
ENSG00000068903 SIRT2 --o
ENSG00000124523 SIRT5 --o
ENSG00000102743 SLC25A15 NonAssociatedWithProgression
ENSG00000151729 SLC25A4 -oo
ENSG00000173473 SMARCC1 o--a
ENSG00000139613 SMARCC2 --o
ENSG00000066117 SMARCD1 NonAssociatedWithProgression
ENSG00000073584 SMARCE1 -oo
ENSG00000072501 SMC1A o--a
ENSG00000108055 SMC3 NonAssociatedWithProgression
ENSG00000113810 SMC4 o+-
ENSG00000070366 SMG6 ---
ENSG00000092531 SNAP23 o+o
ENSG00000099940 SNAP29 o-+
ENSG00000142168 SOD1 NonAssociatedWithProgression
ENSG00000160460 SPTBN4 NonAssociatedWithProgression
ENSG00000122862 SRGN NonAssociatedWithProgression
ENSG00000141298 SSH2 NonAssociatedWithProgression
ENSG00000066923 STAG3 o--b
ENSG00000131748 STARD3 ---
ENSG00000117632 STMN1 o--b
ENSG00000162236 STX5 o--a
ENSG00000092201 SUPT16H o--a
ENSG00000213246 SUPT4H1 o--a
ENSG00000131018 SYNE1 o++b
ENSG00000162227 TAF6L ---
ENSG00000149930 TAOK2 NonAssociatedWithProgression
ENSG00000102125 TAZ o-+
ENSG00000129566 TEP1 +o+
ENSG00000132604 TERF2 o--a
ENSG00000166848 TERF2IP o--b
ENSG00000070759 TESK2 +o+
ENSG00000108064 TFAM NonAssociatedWithProgression
ENSG00000162851 TFB2M NonAssociatedWithProgression
ENSG00000134375 TIMM17A -oo
ENSG00000126768 TIMM17B --o
ENSG00000138297 TIMM23 o--a
ENSG00000104980 TIMM44 ---
ENSG00000105197 TIMM50 ---
ENSG00000092330 TINF2 o--b
ENSG00000198586 TLK1 NonAssociatedWithProgression
ENSG00000170348 TMED10 --o
ENSG00000058804 TMEM48 NonAssociatedWithProgression
ENSG00000154620 TMSB4Y o+o
ENSG00000100216 TOMM22 o--b
ENSG00000025772 TOMM34 o--a
ENSG00000131747 TOP2A o--b
ENSG00000141510 TP53 o--a
ENSG00000072756 TRNT1 o++a
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000112742 TTK o--b
ENSG00000074935 TUBE1 o+o
ENSG00000131462 TUBG1 --o
ENSG00000153575 TUBGCP5 o-o
ENSG00000128159 TUBGCP6 o--a
ENSG00000177889 UBE2N o--a
ENSG00000119541 VPS4B NonAssociatedWithProgression
ENSG00000112290 WASF1 NonAssociatedWithProgression
ENSG00000158195 WASF2 NonAssociatedWithProgression
ENSG00000106299 WASL o+o
ENSG00000147548 WHSC1L1 o--b
ENSG00000115935 WIPF1 -+o
ENSG00000106636 YKT6 o--a
ENSG00000086827 ZW10 NonAssociatedWithProgression
ENSG00000122952 ZWINT o-o