PEACHi
GeneSet NEGATIVE_REGULATION_OF_METABOLIC_PROCESS (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.9 0.04823 124.0 29.0 17.13
DownRegulated -3.2 0.01458 124.0 90.0 73.23
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000166313 APBB1 o-o
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000116584 ARHGEF2 o--b
ENSG00000032219 ARID4A o-+
ENSG00000171681 ATF7IP ---
ENSG00000175054 ATR NonAssociatedWithProgression
ENSG00000124788 ATXN1 oo+
ENSG00000069399 BCL3 NonAssociatedWithProgression
ENSG00000113916 BCL6 +-o
ENSG00000029363 BCLAF1 NonAssociatedWithProgression
ENSG00000183337 BCOR o--a
ENSG00000171634 BPTF NonAssociatedWithProgression
ENSG00000012048 BRCA1 NonAssociatedWithProgression
ENSG00000100211 CBY1 NonAssociatedWithProgression
ENSG00000070831 CDC42 +oo
ENSG00000094804 CDC6 NonAssociatedWithProgression
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000123080 CDKN2C o-o
ENSG00000117724 CENPF o--a
ENSG00000131165 CHMP1A o--a
ENSG00000074054 CLASP1 NonAssociatedWithProgression
ENSG00000149600 COMMD7 oo+
ENSG00000137504 CREBZF NonAssociatedWithProgression
ENSG00000060138 CSDA -o-
ENSG00000102974 CTCF o--b
ENSG00000160967 CUX1 o+o
ENSG00000204209 DAXX o--b
ENSG00000158796 DEDD -o-
ENSG00000136770 DNAJC1 NonAssociatedWithProgression
ENSG00000130816 DNMT1 o-o
ENSG00000117505 DR1 o--a
ENSG00000175550 DRAP1 o--b
ENSG00000101412 E2F1 o--b
ENSG00000169016 E2F6 oo-
ENSG00000086232 EIF2AK1 NonAssociatedWithProgression
ENSG00000172071 EIF2AK3 NonAssociatedWithProgression
ENSG00000141543 EIF4A3 NonAssociatedWithProgression
ENSG00000074800 ENO1 o--b
ENSG00000120616 EPC1 o--b
ENSG00000175595 ERCC4 o-o
ENSG00000125740 FOSB +-o
ENSG00000053254 FOXN3 oo+
ENSG00000140564 FURIN o++a
ENSG00000167491 GATAD2A o--a
ENSG00000001084 GCLC NonAssociatedWithProgression
ENSG00000102393 GLA ---
ENSG00000126603 GLIS2 NonAssociatedWithProgression
ENSG00000112312 GMNN NonAssociatedWithProgression
ENSG00000160007 GRLF1 +o+
ENSG00000107937 GTPBP4 o--b
ENSG00000147099 HDAC8 oo-
ENSG00000119969 HELLS +o+
ENSG00000186834 HEXIM1 o--a
ENSG00000168517 HEXIM2 NonAssociatedWithProgression
ENSG00000189403 HMGB1 o--b
ENSG00000230989 HSBP1 NonAssociatedWithProgression
ENSG00000125968 ID1 o--a
ENSG00000117318 ID3 ---
ENSG00000129351 ILF3 -o-
ENSG00000111653 ING4 o+-
ENSG00000168310 IRF2 o++b
ENSG00000185507 IRF7 ---
ENSG00000153814 JAZF1 ---
ENSG00000140854 KATNB1 o--b
ENSG00000121774 KHDRBS1 NonAssociatedWithProgression
ENSG00000155090 KLF10 o--b
ENSG00000118922 KLF12 o+o
ENSG00000132434 LANCL2 NonAssociatedWithProgression
ENSG00000198728 LDB1 o--b
ENSG00000050405 LIMA1 -+o
ENSG00000101367 MAPRE1 o--b
ENSG00000135679 MDM2 -o-
ENSG00000198625 MDM4 o-o
ENSG00000169057 MECP2 o--a
ENSG00000134138 MEIS2 o++b
ENSG00000133895 MEN1 ---
ENSG00000123933 MXD4 ---
ENSG00000103510 MYST1 o--b
ENSG00000083168 MYST3 +-o
ENSG00000156650 MYST4 NonAssociatedWithProgression
ENSG00000186010 NDUFA13 o-o
ENSG00000186575 NF2 o--b
ENSG00000086102 NFX1 NonAssociatedWithProgression
ENSG00000186416 NKRF o--b
ENSG00000131408 NR1H2 o--a
ENSG00000180530 NRIP1 o++a
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000170515 PA2G4 NonAssociatedWithProgression
ENSG00000120727 PAIP2 NonAssociatedWithProgression
ENSG00000177425 PAWR o++b
ENSG00000156374 PCGF6 o+o
ENSG00000150593 PDCD4 oo-
ENSG00000179094 PER1 ---
ENSG00000142655 PEX14 o++b
ENSG00000167085 PHB NonAssociatedWithProgression
ENSG00000109118 PHF12 o--a
ENSG00000135365 PHF21A ---
ENSG00000140464 PML o-o
ENSG00000143190 POU2F1 NonAssociatedWithProgression
ENSG00000112033 PPARD ---
ENSG00000119383 PPP2R4 ---
ENSG00000152942 RAD17 o--a
ENSG00000172613 RAD9A o--b
ENSG00000139687 RB1 NonAssociatedWithProgression
ENSG00000168214 RBPJ o--b
ENSG00000080298 RFX3 NonAssociatedWithProgression
ENSG00000048649 RSF1 +-o
ENSG00000124813 RUNX2 +oo
ENSG00000163602 RYBP -o-
ENSG00000163191 S100A11 oo-
ENSG00000119335 SET o--b
ENSG00000185187 SIGIRR o--b
ENSG00000169375 SIN3A o--b
ENSG00000096717 SIRT1 +-o
ENSG00000068903 SIRT2 --o
ENSG00000124523 SIRT5 --o
ENSG00000101082 SLA2 o+o
ENSG00000175387 SMAD2 NonAssociatedWithProgression
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000141646 SMAD4 o--b
ENSG00000139613 SMARCC2 --o
ENSG00000073584 SMARCE1 -oo
ENSG00000100603 SNW1 NonAssociatedWithProgression
ENSG00000129515 SNX6 o--a
ENSG00000185338 SOCS1 o--a
ENSG00000142168 SOD1 NonAssociatedWithProgression
ENSG00000168610 STAT3 o--b
ENSG00000111707 SUDS3 o--a
ENSG00000116030 SUMO1 NonAssociatedWithProgression
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000172465 TCEAL1 oo+
ENSG00000141002 TCF25 o-o
ENSG00000132604 TERF2 o--a
ENSG00000166848 TERF2IP o--b
ENSG00000105329 TGFB1 o--a
ENSG00000177426 TGIF1 o+o
ENSG00000102265 TIMP1 o--a
ENSG00000075131 TIPIN NonAssociatedWithProgression
ENSG00000196781 TLE1 o--a
ENSG00000154620 TMSB4Y o+o
ENSG00000163519 TRAT1 NonAssociatedWithProgression
ENSG00000204713 TRIM27 o--a
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000184205 TSPYL2 o--b
ENSG00000153560 UBP1 o-+
ENSG00000087206 UIMC1 o--a
ENSG00000134086 VHL ---
ENSG00000163159 VPS72 o--b
ENSG00000123124 WWP1 -o-
ENSG00000015153 YAF2 -oo
ENSG00000148516 ZEB1 oo-
ENSG00000198081 ZFP161 NonAssociatedWithProgression
ENSG00000165156 ZHX1 NonAssociatedWithProgression
ENSG00000178764 ZHX2 NonAssociatedWithProgression
ENSG00000174306 ZHX3 ---
ENSG00000015171 ZMYND11 NonAssociatedWithProgression
ENSG00000196646 ZNF136 NonAssociatedWithProgression
ENSG00000163848 ZNF148 NonAssociatedWithProgression
ENSG00000103343 ZNF174 o++b
ENSG00000188629 ZNF177 -+o
ENSG00000136870 ZNF189 +o+
ENSG00000166261 ZNF202 ---
ENSG00000179456 ZNF238 o-o
ENSG00000172466 ZNF24 o--b
ENSG00000213096 ZNF254 NonAssociatedWithProgression
ENSG00000162702 ZNF281 o+o
ENSG00000102935 ZNF423 o--b