PEACHi
GeneSet NEGATIVE_REGULATION_OF_CELLULAR_PROCESS (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
oo- -3.6 0.02851 281.0 14.0 5.35
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000108270 AATF o--b
ENSG00000136754 ABI1 NonAssociatedWithProgression
ENSG00000072110 ACTN1 -+o
ENSG00000137845 ADAM10 NonAssociatedWithProgression
ENSG00000204472 AIF1 o--a
ENSG00000204673 AKT1S1 ---
ENSG00000214274 ANG o++b
ENSG00000167772 ANGPTL4 NonAssociatedWithProgression
ENSG00000135046 ANXA1 o+-
ENSG00000196975 ANXA4 NonAssociatedWithProgression
ENSG00000164111 ANXA5 -+o
ENSG00000166313 APBB1 o-o
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000166181 API5 NonAssociatedWithProgression
ENSG00000165527 ARF6 NonAssociatedWithProgression
ENSG00000141522 ARHGDIA ---
ENSG00000111348 ARHGDIB o--b
ENSG00000116584 ARHGEF2 o--b
ENSG00000032219 ARID4A o-+
ENSG00000171681 ATF7IP ---
ENSG00000130770 ATPIF1 o++a
ENSG00000175054 ATR NonAssociatedWithProgression
ENSG00000124788 ATXN1 oo+
ENSG00000169857 AVEN NonAssociatedWithProgression
ENSG00000027847 B4GALT7 o--a
ENSG00000156735 BAG4 ---
ENSG00000163930 BAP1 o--b
ENSG00000138376 BARD1 o--b
ENSG00000142867 BCL10 o+o
ENSG00000171791 BCL2 NonAssociatedWithProgression
ENSG00000171552 BCL2L1 ---
ENSG00000069399 BCL3 NonAssociatedWithProgression
ENSG00000113916 BCL6 +-o
ENSG00000029363 BCLAF1 NonAssociatedWithProgression
ENSG00000183337 BCOR o--a
ENSG00000126581 BECN1 oo+
ENSG00000103429 BFAR o++b
ENSG00000023445 BIRC3 o++a
ENSG00000089685 BIRC5 ---
ENSG00000115760 BIRC6 -+o
ENSG00000125378 BMP4 +-o
ENSG00000113734 BNIP1 o--b
ENSG00000140299 BNIP2 NonAssociatedWithProgression
ENSG00000104765 BNIP3L NonAssociatedWithProgression
ENSG00000171634 BPTF NonAssociatedWithProgression
ENSG00000157764 BRAF oo-
ENSG00000089234 BRAP NonAssociatedWithProgression
ENSG00000012048 BRCA1 NonAssociatedWithProgression
ENSG00000158019 BRE o--a
ENSG00000133639 BTG1 NonAssociatedWithProgression
ENSG00000159388 BTG2 o-o
ENSG00000154640 BTG3 NonAssociatedWithProgression
ENSG00000110888 CAPRIN2 NonAssociatedWithProgression
ENSG00000105483 CARD8 o++a
ENSG00000164305 CASP3 o++b
ENSG00000141582 CBX4 o+-
ENSG00000100211 CBY1 NonAssociatedWithProgression
ENSG00000135535 CD164 oo-
ENSG00000139193 CD27 NonAssociatedWithProgression
ENSG00000178562 CD28 o+o
ENSG00000151465 CDC123 NonAssociatedWithProgression
ENSG00000070831 CDC42 +oo
ENSG00000094804 CDC6 NonAssociatedWithProgression
ENSG00000185324 CDK10 o--a
ENSG00000101391 CDK5RAP1 o--a
ENSG00000105810 CDK6 o--a
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000168564 CDKN2AIP NonAssociatedWithProgression
ENSG00000123080 CDKN2C o-o
ENSG00000100526 CDKN3 NonAssociatedWithProgression
ENSG00000117724 CENPF o--a
ENSG00000172757 CFL1 o-o
ENSG00000003402 CFLAR +-o
ENSG00000100532 CGRRF1 o+o
ENSG00000149554 CHEK1 o+o
ENSG00000131165 CHMP1A o--a
ENSG00000005194 CIAPIN1 o--a
ENSG00000074054 CLASP1 NonAssociatedWithProgression
ENSG00000169504 CLIC4 +oo
ENSG00000188603 CLN3 o++b
ENSG00000155508 CNOT8 oo-
ENSG00000182871 COL18A1 NonAssociatedWithProgression
ENSG00000149600 COMMD7 oo+
ENSG00000137504 CREBZF NonAssociatedWithProgression
ENSG00000060138 CSDA -o-
ENSG00000159692 CTBP1 NonAssociatedWithProgression
ENSG00000175029 CTBP2 o++a
ENSG00000102974 CTCF o--b
ENSG00000055130 CUL1 o++a
ENSG00000108094 CUL2 o+o
ENSG00000036257 CUL3 o--a
ENSG00000139842 CUL4A oo-
ENSG00000166266 CUL5 o--b
ENSG00000160967 CUX1 o+o
ENSG00000129562 DAD1 -oo
ENSG00000204209 DAXX o--b
ENSG00000057019 DCBLD2 o++a
ENSG00000158796 DEDD -o-
ENSG00000160049 DFFA NonAssociatedWithProgression
ENSG00000116133 DHCR24 NonAssociatedWithProgression
ENSG00000100867 DHRS2 NonAssociatedWithProgression
ENSG00000075711 DLG1 NonAssociatedWithProgression
ENSG00000151208 DLG5 o--b
ENSG00000136770 DNAJC1 NonAssociatedWithProgression
ENSG00000130816 DNMT1 o-o
ENSG00000117505 DR1 o--a
ENSG00000175550 DRAP1 o--b
ENSG00000135144 DTX1 o--b
ENSG00000101412 E2F1 o--b
ENSG00000169016 E2F6 oo-
ENSG00000124802 EEF1E1 NonAssociatedWithProgression
ENSG00000086232 EIF2AK1 NonAssociatedWithProgression
ENSG00000055332 EIF2AK2 o--a
ENSG00000172071 EIF2AK3 NonAssociatedWithProgression
ENSG00000141543 EIF4A3 NonAssociatedWithProgression
ENSG00000110321 EIF4G2 o+-
ENSG00000142227 EMP3 o--b
ENSG00000074800 ENO1 o--b
ENSG00000120616 EPC1 o--b
ENSG00000082805 ERC1 o--a
ENSG00000175595 ERCC4 o-o
ENSG00000134899 ERCC5 NonAssociatedWithProgression
ENSG00000134954 ETS1 NonAssociatedWithProgression
ENSG00000185104 FAF1 o--a
ENSG00000162894 FAIM3 NonAssociatedWithProgression
ENSG00000026103 FAS NonAssociatedWithProgression
ENSG00000125740 FOSB +-o
ENSG00000053254 FOXN3 oo+
ENSG00000184481 FOXO4 --o
ENSG00000167996 FTH1 oo-
ENSG00000140564 FURIN o++a
ENSG00000116717 GADD45A o+o
ENSG00000180447 GAS1 o++b
ENSG00000007237 GAS7 ---
ENSG00000141013 GAS8 NonAssociatedWithProgression
ENSG00000167491 GATAD2A o--a
ENSG00000001084 GCLC NonAssociatedWithProgression
ENSG00000102393 GLA ---
ENSG00000126603 GLIS2 NonAssociatedWithProgression
ENSG00000124767 GLO1 o-o
ENSG00000104499 GML o++b
ENSG00000112312 GMNN NonAssociatedWithProgression
ENSG00000147437 GNRH1 o+o
ENSG00000136235 GPNMB o++b
ENSG00000233276 GPX1 ---
ENSG00000160007 GRLF1 +o+
ENSG00000082701 GSK3B -o-
ENSG00000084207 GSTP1 o--a
ENSG00000107937 GTPBP4 o--b
ENSG00000134248 HBXIP o++a
ENSG00000116478 HDAC1 ---
ENSG00000171720 HDAC3 ---
ENSG00000147099 HDAC8 oo-
ENSG00000119969 HELLS +o+
ENSG00000186834 HEXIM1 o--a
ENSG00000168517 HEXIM2 NonAssociatedWithProgression
ENSG00000185359 HGS o--b
ENSG00000110422 HIPK3 NonAssociatedWithProgression
ENSG00000189403 HMGB1 o--b
ENSG00000230989 HSBP1 NonAssociatedWithProgression
ENSG00000166598 HSP90B1 NonAssociatedWithProgression
ENSG00000204388 HSPA1B o--b
ENSG00000113013 HSPA9 o--b
ENSG00000106211 HSPB1 o--b
ENSG00000109854 HTATIP2 o+-
ENSG00000125968 ID1 o--a
ENSG00000117318 ID3 ---
ENSG00000126709 IFI6 oo+
ENSG00000185885 IFITM1 o--a
ENSG00000140443 IGF1R o++b
ENSG00000163453 IGFBP7 NonAssociatedWithProgression
ENSG00000113520 IL4 NonAssociatedWithProgression
ENSG00000129351 ILF3 -o-
ENSG00000153487 ING1 NonAssociatedWithProgression
ENSG00000111653 ING4 o+-
ENSG00000168395 ING5 NonAssociatedWithProgression
ENSG00000173226 IQCB1 +o+
ENSG00000168310 IRF2 o++b
ENSG00000185507 IRF7 ---
ENSG00000153814 JAZF1 ---
ENSG00000152409 JMY o--a
ENSG00000140854 KATNB1 o--b
ENSG00000121774 KHDRBS1 NonAssociatedWithProgression
ENSG00000155090 KLF10 o--b
ENSG00000118922 KLF12 o+o
ENSG00000132434 LANCL2 NonAssociatedWithProgression
ENSG00000150457 LATS2 o++a
ENSG00000122188 LAX1 o+-
ENSG00000198728 LDB1 o--b
ENSG00000050405 LIMA1 -+o
ENSG00000179222 MAGED1 NonAssociatedWithProgression
ENSG00000107643 MAPK8 o+o
ENSG00000101367 MAPRE1 o--b
ENSG00000143384 MCL1 o-o
ENSG00000135679 MDM2 -o-
ENSG00000198625 MDM4 o-o
ENSG00000169057 MECP2 o--a
ENSG00000134138 MEIS2 o++b
ENSG00000133895 MEN1 ---
ENSG00000116688 MFN2 o--b
ENSG00000154305 MIA3 NonAssociatedWithProgression
ENSG00000240972 MIF o--a
ENSG00000070444 MNT NonAssociatedWithProgression
ENSG00000123933 MXD4 ---
ENSG00000119950 MXI1 +-o
ENSG00000136997 MYC o--b
ENSG00000103510 MYST1 o--b
ENSG00000083168 MYST3 +-o
ENSG00000156650 MYST4 NonAssociatedWithProgression
ENSG00000249437 NAIP o+o
ENSG00000104320 NBN NonAssociatedWithProgression
ENSG00000071051 NCK2 o--b
ENSG00000186010 NDUFA13 o-o
ENSG00000213619 NDUFS3 NonAssociatedWithProgression
ENSG00000196712 NF1 o+o
ENSG00000186575 NF2 o--b
ENSG00000109320 NFKB1 o++a
ENSG00000146232 NFKBIE o--b
ENSG00000160949 NFKBIL2 ---
ENSG00000086102 NFX1 NonAssociatedWithProgression
ENSG00000186416 NKRF o--b
ENSG00000087095 NLK oo+
ENSG00000239672 NME1 o--a
ENSG00000011052 NME2 NonAssociatedWithProgression
ENSG00000140939 NOL3 --o
ENSG00000148400 NOTCH1 o+o
ENSG00000134250 NOTCH2 o-o
ENSG00000113971 NPHP3 o++a
ENSG00000181163 NPM1 o--b
ENSG00000131408 NR1H2 o--a
ENSG00000180530 NRIP1 o++a
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000213024 NUP62 o--a
ENSG00000009694 ODZ1 o+-
ENSG00000198836 OPA1 o-+
ENSG00000112038 OPRM1 ---
ENSG00000163113 OTUD7B NonAssociatedWithProgression
ENSG00000170515 PA2G4 NonAssociatedWithProgression
ENSG00000120727 PAIP2 NonAssociatedWithProgression
ENSG00000177425 PAWR o++b
ENSG00000090097 PCBP4 o-o
ENSG00000156374 PCGF6 o+o
ENSG00000150593 PDCD4 oo-
ENSG00000083642 PDS5B NonAssociatedWithProgression
ENSG00000179094 PER1 ---
ENSG00000142655 PEX14 o++b
ENSG00000167085 PHB NonAssociatedWithProgression
ENSG00000109118 PHF12 o--a
ENSG00000135365 PHF21A ---
ENSG00000105647 PIK3R2 o--a
ENSG00000137193 PIM1 o--b
ENSG00000118495 PLAGL1 NonAssociatedWithProgression
ENSG00000122194 PLG o+o
ENSG00000140464 PML o-o
ENSG00000143190 POU2F1 NonAssociatedWithProgression
ENSG00000112033 PPARD ---
ENSG00000115241 PPM1G o--a
ENSG00000087074 PPP1R15A ---
ENSG00000108819 PPP1R9B -+o
ENSG00000167393 PPP2R3B o--a
ENSG00000119383 PPP2R4 ---
ENSG00000131238 PPT1 +-o
ENSG00000167815 PRDX2 --o
ENSG00000067606 PRKCZ ---
ENSG00000180228 PRKRA --o
ENSG00000137492 PRKRIR NonAssociatedWithProgression
ENSG00000080815 PSEN1 o-o
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000081237 PTPRC o+o
ENSG00000116260 QSOX1 o-+
ENSG00000136238 RAC1 NonAssociatedWithProgression
ENSG00000152942 RAD17 o--a
ENSG00000172613 RAD9A o--b
ENSG00000145715 RASA1 NonAssociatedWithProgression
ENSG00000068028 RASSF1 o--a
ENSG00000139687 RB1 NonAssociatedWithProgression
ENSG00000162521 RBBP4 NonAssociatedWithProgression
ENSG00000168214 RBPJ o--b
ENSG00000173039 RELA o--a
ENSG00000080298 RFX3 NonAssociatedWithProgression
ENSG00000143878 RHOB +-o
ENSG00000168421 RHOH o--b
ENSG00000172602 RND1 -o-
ENSG00000114125 RNF7 o+o
ENSG00000215695 RSC1A1 +-o
ENSG00000048649 RSF1 +-o
ENSG00000114993 RTKN NonAssociatedWithProgression
ENSG00000115310 RTN4 +oo
ENSG00000124813 RUNX2 +oo
ENSG00000020633 RUNX3 o--b
ENSG00000163602 RYBP -o-
ENSG00000163191 S100A11 oo-
ENSG00000187764 SEMA4D o++b
ENSG00000170542 SERPINB9 o++b
ENSG00000179833 SERTAD2 NonAssociatedWithProgression
ENSG00000167565 SERTAD3 NonAssociatedWithProgression
ENSG00000119335 SET o--b
ENSG00000097033 SH3GLB1 o+o
ENSG00000185187 SIGIRR o--b
ENSG00000169375 SIN3A o--b
ENSG00000096717 SIRT1 +-o
ENSG00000068903 SIRT2 --o
ENSG00000124523 SIRT5 --o
ENSG00000101082 SLA2 o+o
ENSG00000175387 SMAD2 NonAssociatedWithProgression
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000141646 SMAD4 o--b
ENSG00000139613 SMARCC2 --o
ENSG00000073584 SMARCE1 -oo
ENSG00000100603 SNW1 NonAssociatedWithProgression
ENSG00000129515 SNX6 o--a
ENSG00000185338 SOCS1 o--a
ENSG00000171150 SOCS5 oo-
ENSG00000142168 SOD1 NonAssociatedWithProgression
ENSG00000159140 SON NonAssociatedWithProgression
ENSG00000072195 SPEG NonAssociatedWithProgression
ENSG00000197471 SPN o--a
ENSG00000168610 STAT3 o--b
ENSG00000109689 STIM2 --o
ENSG00000118046 STK11 o--a
ENSG00000111707 SUDS3 o--a
ENSG00000116030 SUMO1 NonAssociatedWithProgression
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000135090 TAOK3 o+o
ENSG00000106052 TAX1BP1 o+o
ENSG00000213977 TAX1BP3 ---
ENSG00000154144 TBRG1 o--b
ENSG00000136270 TBRG4 o--a
ENSG00000172465 TCEAL1 oo+
ENSG00000141002 TCF25 o-o
ENSG00000132604 TERF2 o--a
ENSG00000166848 TERF2IP o--b
ENSG00000105329 TGFB1 o--a
ENSG00000177426 TGIF1 o+o
ENSG00000102265 TIMP1 o--a
ENSG00000075131 TIPIN NonAssociatedWithProgression
ENSG00000196781 TLE1 o--a
ENSG00000154620 TMSB4Y o+o
ENSG00000118503 TNFAIP3 o--a
ENSG00000145779 TNFAIP8 o++b
ENSG00000141232 TOB1 NonAssociatedWithProgression
ENSG00000141510 TP53 o--a
ENSG00000143514 TP53BP2 oo-
ENSG00000175274 TP53I11 ---
ENSG00000133112 TPT1 oo-
ENSG00000163519 TRAT1 NonAssociatedWithProgression
ENSG00000170855 TRIAP1 o--b
ENSG00000204713 TRIM27 o--a
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000184205 TSPYL2 o--b
ENSG00000239264 TXNDC5 o--b
ENSG00000153560 UBP1 o-+
ENSG00000152332 UHMK1 o--a
ENSG00000087206 UIMC1 o--a
ENSG00000120800 UTP20 NonAssociatedWithProgression
ENSG00000035403 VCL o++a
ENSG00000112715 VEGFA +-o
ENSG00000134086 VHL ---
ENSG00000163159 VPS72 o--b
ENSG00000140105 WARS NonAssociatedWithProgression
ENSG00000123124 WWP1 -o-
ENSG00000015153 YAF2 -oo
ENSG00000128245 YWHAH +-o
ENSG00000164924 YWHAZ o--b
ENSG00000116809 ZBTB17 o--b
ENSG00000148516 ZEB1 oo-
ENSG00000198081 ZFP161 NonAssociatedWithProgression
ENSG00000165156 ZHX1 NonAssociatedWithProgression
ENSG00000178764 ZHX2 NonAssociatedWithProgression
ENSG00000174306 ZHX3 ---
ENSG00000015171 ZMYND11 NonAssociatedWithProgression
ENSG00000196646 ZNF136 NonAssociatedWithProgression
ENSG00000163848 ZNF148 NonAssociatedWithProgression
ENSG00000103343 ZNF174 o++b
ENSG00000188629 ZNF177 -+o
ENSG00000136870 ZNF189 +o+
ENSG00000166261 ZNF202 ---
ENSG00000179456 ZNF238 o-o
ENSG00000172466 ZNF24 o--b
ENSG00000213096 ZNF254 NonAssociatedWithProgression
ENSG00000162702 ZNF281 o+o
ENSG00000102935 ZNF423 o--b