PEACHi
GeneSet Metabolism of proteins (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -4.5 0.00318 248.0 58.0 35.22
DownRegulated -7.2 0.0 248.0 185.0 146.45
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000100412 ACO2 -oo
ENSG00000075624 ACTB o--b
ENSG00000253710 ALG11 o--a
ENSG00000101901 ALG13 -oo
ENSG00000172339 ALG14 +o+
ENSG00000119523 ALG2 NonAssociatedWithProgression
ENSG00000214160 ALG3 o--a
ENSG00000120697 ALG5 o-o
ENSG00000088035 ALG6 NonAssociatedWithProgression
ENSG00000159063 ALG8 o--a
ENSG00000185009 AP3M1 o--a
ENSG00000124198 ARFGEF2 o+o
ENSG00000152234 ATP5A1 -o-
ENSG00000110955 ATP5B o--b
ENSG00000159199 ATP5G1 NonAssociatedWithProgression
ENSG00000170340 B3GNT2 +oo
ENSG00000175711 B3GNTL1 --o
ENSG00000086062 B4GALT1 ---
ENSG00000158850 B4GALT3 o--a
ENSG00000121578 B4GALT4 o--b
ENSG00000158470 B4GALT5 o++b
ENSG00000118276 B4GALT6 NonAssociatedWithProgression
ENSG00000074582 BCS1L o-o
ENSG00000106392 C1GALT1 o++b
ENSG00000171155 C1GALT1C1 o++b
ENSG00000179218 CALR ---
ENSG00000127022 CANX NonAssociatedWithProgression
ENSG00000166226 CCT2 o--a
ENSG00000163468 CCT3 NonAssociatedWithProgression
ENSG00000115484 CCT4 o--a
ENSG00000150753 CCT5 o--a
ENSG00000146731 CCT6A NonAssociatedWithProgression
ENSG00000135624 CCT7 ---
ENSG00000156261 CCT8 o--b
ENSG00000173085 COQ2 o--b
ENSG00000138495 COX17 o+-
ENSG00000062485 CS +-o
ENSG00000179091 CYC1 ---
ENSG00000129562 DAD1 -oo
ENSG00000244038 DDOST o--a
ENSG00000095059 DHPS o-o
ENSG00000205981 DNAJC19 o--b
ENSG00000129932 DOHH ---
ENSG00000175283 DOLK NonAssociatedWithProgression
ENSG00000167130 DOLPP1 NonAssociatedWithProgression
ENSG00000172269 DPAGT1 -+o
ENSG00000000419 DPM1 o+-
ENSG00000136908 DPM2 o--a
ENSG00000179085 DPM3 o-o
ENSG00000134109 EDEM1 o--b
ENSG00000088298 EDEM2 o--a
ENSG00000116406 EDEM3 o--a
ENSG00000156508 EEF1A1 o--a
ENSG00000114942 EEF1B2 -o-
ENSG00000104529 EEF1D o--a
ENSG00000167658 EEF2 oo-
ENSG00000173674 EIF1AX ---
ENSG00000111361 EIF2B1 -+o
ENSG00000119718 EIF2B2 o--a
ENSG00000070785 EIF2B3 NonAssociatedWithProgression
ENSG00000115211 EIF2B4 o-o
ENSG00000145191 EIF2B5 ---
ENSG00000134001 EIF2S1 o--a
ENSG00000125977 EIF2S2 NonAssociatedWithProgression
ENSG00000130741 EIF2S3 o--a
ENSG00000107581 EIF3A NonAssociatedWithProgression
ENSG00000106263 EIF3B o--a
ENSG00000184110 EIF3C o--b
ENSG00000100353 EIF3D o--a
ENSG00000104408 EIF3E +-o
ENSG00000130811 EIF3G ---
ENSG00000147677 EIF3H o+o
ENSG00000084623 EIF3I -o-
ENSG00000104131 EIF3J oo-
ENSG00000178982 EIF3K o+o
ENSG00000161960 EIF4A1 -o-
ENSG00000156976 EIF4A2 o+o
ENSG00000063046 EIF4B o--a
ENSG00000187840 EIF4EBP1 o--b
ENSG00000114867 EIF4G1 ---
ENSG00000106682 EIF4H NonAssociatedWithProgression
ENSG00000100664 EIF5 o--b
ENSG00000132507 EIF5A o--a
ENSG00000163577 EIF5A2 o+-
ENSG00000158417 EIF5B o--b
ENSG00000120705 ETF1 o--a
ENSG00000149806 FAU o-o
ENSG00000005812 FBXL3 o--a
ENSG00000118564 FBXL5 o-+
ENSG00000151876 FBXO4 ---
ENSG00000119402 FBXW2 +-o
ENSG00000107829 FBXW4 o--a
ENSG00000159069 FBXW5 o-o
ENSG00000109670 FBXW7 o+-
ENSG00000140564 FURIN o++a
ENSG00000033170 FUT8 -+o
ENSG00000132286 FXC1 o--a
ENSG00000165060 FXN -oo
ENSG00000141429 GALNT1 NonAssociatedWithProgression
ENSG00000164574 GALNT10 o++a
ENSG00000119514 GALNT12 NonAssociatedWithProgression
ENSG00000143641 GALNT2 o--a
ENSG00000109586 GALNT7 o--b
ENSG00000110328 GALNTL4 oo+
ENSG00000089597 GANAB o--a
ENSG00000127554 GFER ---
ENSG00000198380 GFPT1 NonAssociatedWithProgression
ENSG00000115486 GGCX o+o
ENSG00000144591 GMPPA --o
ENSG00000173540 GMPPB o--b
ENSG00000109519 GRPEL1 o--b
ENSG00000164284 GRPEL2 o-o
ENSG00000189369 GSPT2 o+-
ENSG00000100209 HSCB o+-
ENSG00000113013 HSPA9 o--b
ENSG00000144381 HSPD1 o--b
ENSG00000067829 IDH3G ---
ENSG00000074695 LMAN1 o-o
ENSG00000102910 LONP2 o--a
ENSG00000111885 MAN1A1 o++a
ENSG00000198162 MAN1A2 o+o
ENSG00000177239 MAN1B1 ---
ENSG00000112893 MAN2A1 -o-
ENSG00000172469 MANEA NonAssociatedWithProgression
ENSG00000180398 MCFD2 NonAssociatedWithProgression
ENSG00000131446 MGAT1 o--a
ENSG00000168282 MGAT2 o--b
ENSG00000071073 MGAT4A NonAssociatedWithProgression
ENSG00000161013 MGAT4B ---
ENSG00000110917 MLEC o--b
ENSG00000115275 MOGS o-o
ENSG00000178802 MPI ---
ENSG00000173171 MTX1 o--a
ENSG00000128654 MTX2 o++b
ENSG00000185499 MUC1 +-o
ENSG00000176945 MUC20 oo+
ENSG00000101361 NOP56 o--b
ENSG00000070756 PABPC1 o--b
ENSG00000167004 PDIA3 o--a
ENSG00000113068 PFDN1 o-o
ENSG00000143256 PFDN2 NonAssociatedWithProgression
ENSG00000101132 PFDN4 NonAssociatedWithProgression
ENSG00000123349 PFDN5 NonAssociatedWithProgression
ENSG00000204220 PFDN6 ---
ENSG00000197121 PGAP1 NonAssociatedWithProgression
ENSG00000013375 PGM3 +o+
ENSG00000165195 PIGA NonAssociatedWithProgression
ENSG00000069943 PIGB o++b
ENSG00000135845 PIGC oo+
ENSG00000151665 PIGF -+o
ENSG00000174227 PIGG o++b
ENSG00000100564 PIGH NonAssociatedWithProgression
ENSG00000142892 PIGK -+o
ENSG00000108474 PIGL o--b
ENSG00000143315 PIGM -+o
ENSG00000197563 PIGN --o
ENSG00000165282 PIGO ---
ENSG00000185808 PIGP NonAssociatedWithProgression
ENSG00000007541 PIGQ ---
ENSG00000087111 PIGS o-o
ENSG00000124155 PIGT o--b
ENSG00000101464 PIGU o--a
ENSG00000060642 PIGV NonAssociatedWithProgression
ENSG00000163964 PIGX o--a
ENSG00000100417 PMM1 NonAssociatedWithProgression
ENSG00000140650 PMM2 o--b
ENSG00000165688 PMPCA o--a
ENSG00000105819 PMPCB o+o
ENSG00000138073 PREB o--a
ENSG00000130175 PRKCSH o--b
ENSG00000163933 RFT1 --o
ENSG00000147403 RPL10 o-o
ENSG00000198755 RPL10A NonAssociatedWithProgression
ENSG00000142676 RPL11 o--b
ENSG00000197958 RPL12 NonAssociatedWithProgression
ENSG00000167526 RPL13 o--b
ENSG00000142541 RPL13A NonAssociatedWithProgression
ENSG00000188846 RPL14 o--a
ENSG00000174748 RPL15 o--a
ENSG00000215472 RPL17 o-o
ENSG00000105640 RPL18A o-o
ENSG00000108298 RPL19 o-o
ENSG00000122026 RPL21 o--a
ENSG00000116251 RPL22 +-o
ENSG00000125691 RPL23 NonAssociatedWithProgression
ENSG00000198242 RPL23A o--a
ENSG00000114391 RPL24 o--b
ENSG00000161970 RPL26 o-o
ENSG00000131469 RPL27 NonAssociatedWithProgression
ENSG00000166441 RPL27A o--a
ENSG00000108107 RPL28 o--b
ENSG00000162244 RPL29 o--a
ENSG00000100316 RPL3 -o-
ENSG00000156482 RPL30 o++b
ENSG00000071082 RPL31 o-+
ENSG00000144713 RPL32 NonAssociatedWithProgression
ENSG00000109475 RPL34 NonAssociatedWithProgression
ENSG00000136942 RPL35 o--b
ENSG00000182899 RPL35A NonAssociatedWithProgression
ENSG00000130255 RPL36 o-o
ENSG00000241343 RPL36A ---
ENSG00000145592 RPL37 NonAssociatedWithProgression
ENSG00000197756 RPL37A NonAssociatedWithProgression
ENSG00000198918 RPL39 o-+
ENSG00000174444 RPL4 o--b
ENSG00000122406 RPL5 NonAssociatedWithProgression
ENSG00000089009 RPL6 o--b
ENSG00000147604 RPL7 NonAssociatedWithProgression
ENSG00000148303 RPL7A -o-
ENSG00000161016 RPL8 ---
ENSG00000163682 RPL9 NonAssociatedWithProgression
ENSG00000089157 RPLP0 o--b
ENSG00000137818 RPLP1 NonAssociatedWithProgression
ENSG00000177600 RPLP2 NonAssociatedWithProgression
ENSG00000163902 RPN1 o-o
ENSG00000118705 RPN2 o--a
ENSG00000124614 RPS10 NonAssociatedWithProgression
ENSG00000142534 RPS11 o--a
ENSG00000112306 RPS12 o--a
ENSG00000110700 RPS13 NonAssociatedWithProgression
ENSG00000164587 RPS14 -o-
ENSG00000115268 RPS15 NonAssociatedWithProgression
ENSG00000134419 RPS15A o+-
ENSG00000105193 RPS16 o--b
ENSG00000231500 RPS18 o-o
ENSG00000105372 RPS19 -o-
ENSG00000140988 RPS2 o--a
ENSG00000008988 RPS20 o--a
ENSG00000186468 RPS23 o-o
ENSG00000138326 RPS24 NonAssociatedWithProgression
ENSG00000197728 RPS26 NonAssociatedWithProgression
ENSG00000177954 RPS27 o-o
ENSG00000143947 RPS27A o+o
ENSG00000233927 RPS28 o-o
ENSG00000213741 RPS29 NonAssociatedWithProgression
ENSG00000149273 RPS3 o--b
ENSG00000145425 RPS3A o-o
ENSG00000198034 RPS4X NonAssociatedWithProgression
ENSG00000129824 RPS4Y1 o--a
ENSG00000083845 RPS5 o--a
ENSG00000137154 RPS6 o--a
ENSG00000171863 RPS7 o--a
ENSG00000142937 RPS8 NonAssociatedWithProgression
ENSG00000170889 RPS9 o--b
ENSG00000168028 RPSA o--b
ENSG00000100347 SAMM50 NonAssociatedWithProgression
ENSG00000152700 SAR1B o++b
ENSG00000140612 SEC11A oo-
ENSG00000166562 SEC11C NonAssociatedWithProgression
ENSG00000157020 SEC13 --o
ENSG00000100934 SEC23A o++b
ENSG00000113615 SEC24A NonAssociatedWithProgression
ENSG00000138802 SEC24B NonAssociatedWithProgression
ENSG00000176986 SEC24C ---
ENSG00000150961 SEC24D NonAssociatedWithProgression
ENSG00000138674 SEC31A o+o
ENSG00000058262 SEC61A1 ---
ENSG00000065665 SEC61A2 +o+
ENSG00000106803 SEC61B o++a
ENSG00000132432 SEC61G NonAssociatedWithProgression
ENSG00000204351 SKIV2L -oo
ENSG00000115840 SLC25A12 o++a
ENSG00000004864 SLC25A13 NonAssociatedWithProgression
ENSG00000151729 SLC25A4 -oo
ENSG00000169100 SLC25A6 o-o
ENSG00000114902 SPCS1 o-o
ENSG00000129128 SPCS3 ---
ENSG00000140319 SRP14 NonAssociatedWithProgression
ENSG00000153037 SRP19 NonAssociatedWithProgression
ENSG00000100883 SRP54 -+o
ENSG00000167881 SRP68 o-+
ENSG00000174780 SRP72 o--b
ENSG00000143742 SRP9 NonAssociatedWithProgression
ENSG00000182934 SRPR o--a
ENSG00000144867 SRPRB NonAssociatedWithProgression
ENSG00000124783 SSR1 -+o
ENSG00000163479 SSR2 o--b
ENSG00000114850 SSR3 NonAssociatedWithProgression
ENSG00000180879 SSR4 ---
ENSG00000008513 ST3GAL1 +oo
ENSG00000157350 ST3GAL2 NonAssociatedWithProgression
ENSG00000126091 ST3GAL3 --o
ENSG00000110080 ST3GAL4 o-o
ENSG00000073849 ST6GAL1 NonAssociatedWithProgression
ENSG00000134910 STT3A NonAssociatedWithProgression
ENSG00000102125 TAZ o-+
ENSG00000171530 TBCA NonAssociatedWithProgression
ENSG00000105254 TBCB NonAssociatedWithProgression
ENSG00000124659 TBCC o--a
ENSG00000141556 TBCD o--b
ENSG00000116957 TBCE o--a
ENSG00000120438 TCP1 -o-
ENSG00000134809 TIMM10 o-o
ENSG00000099800 TIMM13 o--a
ENSG00000134375 TIMM17A -oo
ENSG00000126768 TIMM17B --o
ENSG00000138297 TIMM23 o--a
ENSG00000104980 TIMM44 ---
ENSG00000105197 TIMM50 ---
ENSG00000126953 TIMM8A NonAssociatedWithProgression
ENSG00000150779 TIMM8B --o
ENSG00000100575 TIMM9 -+o
ENSG00000173726 TOMM20 +-o
ENSG00000100216 TOMM22 o--b
ENSG00000130204 TOMM40 o--a
ENSG00000214736 TOMM6 o--b
ENSG00000196683 TOMM7 NonAssociatedWithProgression
ENSG00000154174 TOMM70A o+-
ENSG00000067167 TRAM1 NonAssociatedWithProgression
ENSG00000167552 TUBA1A +oo
ENSG00000123416 TUBA1B NonAssociatedWithProgression
ENSG00000167553 TUBA1C o--b
ENSG00000127824 TUBA4A NonAssociatedWithProgression
ENSG00000137267 TUBB2A NonAssociatedWithProgression
ENSG00000137285 TUBB2B oo+
ENSG00000127589 TUBB4Q o--a
ENSG00000176014 TUBB6 NonAssociatedWithProgression
ENSG00000117143 UAP1 o++a
ENSG00000221983 UBA52 o--a
ENSG00000136731 UGGT1 NonAssociatedWithProgression
ENSG00000102226 USP11 o-o
ENSG00000155959 VBP1 o+-
ENSG00000213585 VDAC1 --o
ENSG00000167397 VKORC1 o-o
ENSG00000088930 XRN2 NonAssociatedWithProgression