PEACHi
GeneSet MITOCHONDRION (GO_-_Cellular_Component.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
--o -3.2 0.01679 208.0 15.0 6.38
o--a -3.2 0.01679 208.0 46.0 29.54
DownRegulated -3.3 0.0099 208.0 145.0 122.83
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000183044 ABAT o++a
ENSG00000131269 ABCB7 o-o
ENSG00000197150 ABCB8 o-o
ENSG00000164163 ABCE1 NonAssociatedWithProgression
ENSG00000033050 ABCF2 o--a
ENSG00000117054 ACADM o--b
ENSG00000122971 ACADS --o
ENSG00000196177 ACADSB oo+
ENSG00000072778 ACADVL o--b
ENSG00000075239 ACAT1 NonAssociatedWithProgression
ENSG00000196636 ACN9 o++b
ENSG00000100412 ACO2 -oo
ENSG00000119673 ACOT2 --o
ENSG00000162836 ACP6 o-+
ENSG00000141385 AFG3L2 o--b
ENSG00000155189 AGPAT5 -o-
ENSG00000156709 AIFM1 NonAssociatedWithProgression
ENSG00000147853 AK3 o--b
ENSG00000112294 ALDH5A1 o++b
ENSG00000242110 AMACR -oo
ENSG00000145020 AMT ---
ENSG00000081181 ARG2 NonAssociatedWithProgression
ENSG00000152234 ATP5A1 -o-
ENSG00000110955 ATP5B o--b
ENSG00000165629 ATP5C1 NonAssociatedWithProgression
ENSG00000099624 ATP5D o--a
ENSG00000124172 ATP5E NonAssociatedWithProgression
ENSG00000116459 ATP5F1 NonAssociatedWithProgression
ENSG00000159199 ATP5G1 NonAssociatedWithProgression
ENSG00000135390 ATP5G2 oo-
ENSG00000154518 ATP5G3 NonAssociatedWithProgression
ENSG00000154723 ATP5J o+o
ENSG00000241837 ATP5O +o+
ENSG00000130770 ATPIF1 o++a
ENSG00000030110 BAK1 o--b
ENSG00000105327 BBC3 +oo
ENSG00000105552 BCAT2 o--a
ENSG00000248098 BCKDHA o-o
ENSG00000083123 BCKDHB o++a
ENSG00000103507 BCKDK o--a
ENSG00000171791 BCL2 NonAssociatedWithProgression
ENSG00000171552 BCL2L1 ---
ENSG00000074582 BCS1L o-o
ENSG00000164039 BDH2 o++b
ENSG00000015475 BID -oo
ENSG00000104765 BNIP3L NonAssociatedWithProgression
ENSG00000137274 BPHL o--b
ENSG00000005379 BZRAP1 o--a
ENSG00000113845 C3orf1 o++b
ENSG00000179152 C3orf23 ---
ENSG00000144559 C3orf31 NonAssociatedWithProgression
ENSG00000110888 CAPRIN2 NonAssociatedWithProgression
ENSG00000165806 CASP7 o-o
ENSG00000064012 CASP8 +-o
ENSG00000106554 CHCHD3 o-o
ENSG00000122873 CISD1 NonAssociatedWithProgression
ENSG00000188603 CLN3 o++b
ENSG00000166855 CLPX NonAssociatedWithProgression
ENSG00000167113 COQ4 o--a
ENSG00000119723 COQ6 o--a
ENSG00000167186 COQ7 o--b
ENSG00000166260 COX11 NonAssociatedWithProgression
ENSG00000014919 COX15 NonAssociatedWithProgression
ENSG00000163626 COX18 o--b
ENSG00000131148 COX4NB o-+
ENSG00000080819 CPOX NonAssociatedWithProgression
ENSG00000110090 CPT1A --o
ENSG00000205560 CPT1B o--a
ENSG00000008405 CRY1 NonAssociatedWithProgression
ENSG00000062485 CS +-o
ENSG00000179091 CYC1 ---
ENSG00000172115 CYCS o--b
ENSG00000180902 D2HGDH NonAssociatedWithProgression
ENSG00000137992 DBT -o-
ENSG00000114956 DGUOK NonAssociatedWithProgression
ENSG00000157326 DHRS4 o--b
ENSG00000184047 DIABLO o--a
ENSG00000091140 DLD NonAssociatedWithProgression
ENSG00000103423 DNAJA3 NonAssociatedWithProgression
ENSG00000205981 DNAJC19 o--b
ENSG00000128951 DUT o--a
ENSG00000127884 ECHS1 o--a
ENSG00000130159 ECSIT o--a
ENSG00000140374 ETFA NonAssociatedWithProgression
ENSG00000161513 FDXR -oo
ENSG00000091483 FH o+-
ENSG00000172500 FIBP --o
ENSG00000214253 FIS1 --o
ENSG00000136877 FPGS o--a
ENSG00000165060 FXN -oo
ENSG00000146729 GBAS o+o
ENSG00000105607 GCDH NonAssociatedWithProgression
ENSG00000165678 GHITM o+o
ENSG00000023572 GLRX2 -+o
ENSG00000182512 GLRX5 NonAssociatedWithProgression
ENSG00000148672 GLUD1 o+o
ENSG00000125166 GOT2 o--a
ENSG00000167468 GPX4 o--b
ENSG00000109519 GRPEL1 o--b
ENSG00000100577 GSTZ1 o-o
ENSG00000138796 HADH --o
ENSG00000138029 HADHB o-o
ENSG00000143575 HAX1 ---
ENSG00000137133 HINT2 o-o
ENSG00000100209 HSCB o+-
ENSG00000072506 HSD17B10 o--b
ENSG00000204388 HSPA1B o--b
ENSG00000113013 HSPA9 o--b
ENSG00000144381 HSPD1 o--b
ENSG00000115541 HSPE1 o+-
ENSG00000115317 HTRA2 o--a
ENSG00000182054 IDH2 NonAssociatedWithProgression
ENSG00000101365 IDH3B NonAssociatedWithProgression
ENSG00000126709 IFI6 oo+
ENSG00000132305 IMMT NonAssociatedWithProgression
ENSG00000136003 ISCU o+o
ENSG00000065427 KARS o-o
ENSG00000081791 KIAA0141 o++a
ENSG00000158941 KIAA1967 o--a
ENSG00000087299 L2HGDH o++b
ENSG00000168924 LETM1 ---
ENSG00000196365 LONP1 o--b
ENSG00000138095 LRPPRC NonAssociatedWithProgression
ENSG00000152428 MARS2 NonAssociatedWithProgression
ENSG00000100294 MCAT o--b
ENSG00000143384 MCL1 o-o
ENSG00000116353 MECR ---
ENSG00000116688 MFN2 o--b
ENSG00000027001 MIPEP -oo
ENSG00000115204 MPV17 --o
ENSG00000159111 MRPL10 o--a
ENSG00000183093 MRPL12 ---
ENSG00000214026 MRPL23 ---
ENSG00000106591 MRPL32 NonAssociatedWithProgression
ENSG00000185608 MRPL40 NonAssociatedWithProgression
ENSG00000182154 MRPL41 ---
ENSG00000198015 MRPL42 o--a
ENSG00000111639 MRPL51 NonAssociatedWithProgression
ENSG00000172590 MRPL52 oo+
ENSG00000162910 MRPL55 o--a
ENSG00000048544 MRPS10 -o-
ENSG00000181991 MRPS11 o--a
ENSG00000128626 MRPS12 o--a
ENSG00000116898 MRPS15 o--b
ENSG00000182180 MRPS16 --o
ENSG00000096080 MRPS18A NonAssociatedWithProgression
ENSG00000163319 MRPS18C NonAssociatedWithProgression
ENSG00000175110 MRPS22 o--a
ENSG00000062582 MRPS24 o--a
ENSG00000147586 MRPS28 o+o
ENSG00000102738 MRPS31 o+o
ENSG00000061794 MRPS35 o--a
ENSG00000134056 MRPS36 -+o
ENSG00000148450 MSRB2 o--a
ENSG00000174099 MSRB3 o+o
ENSG00000125459 MSTO1 NonAssociatedWithProgression
ENSG00000137409 MTCH1 NonAssociatedWithProgression
ENSG00000127989 MTERF o--a
ENSG00000100714 MTHFD1 -+o
ENSG00000065911 MTHFD2 +-o
ENSG00000085760 MTIF2 -+o
ENSG00000122033 MTIF3 o+-
ENSG00000120662 MTRF1 o++b
ENSG00000128654 MTX2 o++b
ENSG00000146085 MUT NonAssociatedWithProgression
ENSG00000134265 NAPG o-+
ENSG00000125356 NDUFA1 o+o
ENSG00000174886 NDUFA11 o-o
ENSG00000186010 NDUFA13 o-o
ENSG00000131495 NDUFA2 o--b
ENSG00000189043 NDUFA4 -+o
ENSG00000184983 NDUFA6 o++b
ENSG00000119421 NDUFA8 oo+
ENSG00000139180 NDUFA9 o--a
ENSG00000023228 NDUFS1 o+o
ENSG00000158864 NDUFS2 --o
ENSG00000213619 NDUFS3 NonAssociatedWithProgression
ENSG00000164258 NDUFS4 NonAssociatedWithProgression
ENSG00000168653 NDUFS5 o--a
ENSG00000115286 NDUFS7 ---
ENSG00000110717 NDUFS8 o--a
ENSG00000167792 NDUFV1 --o
ENSG00000244005 NFS1 NonAssociatedWithProgression
ENSG00000184117 NIPSNAP1 o--a
ENSG00000103202 NME4 --o
ENSG00000112992 NNT -+o
ENSG00000113580 NR3C1 o--a
ENSG00000065154 OAT o-o
ENSG00000105953 OGDH ---
ENSG00000198836 OPA1 o-+
ENSG00000155463 OXA1L +o+
ENSG00000083720 OXCT1 -+o
ENSG00000151093 OXSM NonAssociatedWithProgression
ENSG00000173599 PC o--a
ENSG00000114054 PCCB NonAssociatedWithProgression
ENSG00000131828 PDHA1 o+-
ENSG00000152256 PDK1 NonAssociatedWithProgression
ENSG00000067992 PDK3 o++b
ENSG00000198721 PECI o++a
ENSG00000059691 PET112L -o-
ENSG00000087157 PGS1 o--a
ENSG00000167085 PHB NonAssociatedWithProgression
ENSG00000215021 PHB2 ---
ENSG00000102309 PIN4 -+o
ENSG00000107959 PITRM1 NonAssociatedWithProgression
ENSG00000141682 PMAIP1 oo-
ENSG00000165688 PMPCA o--a
ENSG00000140521 POLG o--b
ENSG00000136480 POLG2 NonAssociatedWithProgression
ENSG00000143224 PPOX +o+
ENSG00000126432 PRDX5 o--a
ENSG00000169230 PRELID1 o--b
ENSG00000080815 PSEN1 o-o
ENSG00000148334 PTGES2 NonAssociatedWithProgression
ENSG00000150787 PTS NonAssociatedWithProgression
ENSG00000132155 RAF1 NonAssociatedWithProgression
ENSG00000126858 RHOT1 NonAssociatedWithProgression
ENSG00000140983 RHOT2 o--b
ENSG00000123453 SARDH o--a
ENSG00000133028 SCO1 NonAssociatedWithProgression
ENSG00000130489 SCO2 o-+
ENSG00000073578 SDHA o-o
ENSG00000117118 SDHB NonAssociatedWithProgression
ENSG00000143252 SDHC o--b
ENSG00000204370 SDHD NonAssociatedWithProgression
ENSG00000182199 SHMT2 o--a
ENSG00000108528 SLC25A11 ---
ENSG00000115840 SLC25A12 o++a
ENSG00000004864 SLC25A13 NonAssociatedWithProgression
ENSG00000102078 SLC25A14 o-o
ENSG00000102743 SLC25A15 NonAssociatedWithProgression
ENSG00000177542 SLC25A22 NonAssociatedWithProgression
ENSG00000151729 SLC25A4 -oo
ENSG00000169100 SLC25A6 o-o
ENSG00000198689 SLC9A6 NonAssociatedWithProgression
ENSG00000100335 SMCR7L NonAssociatedWithProgression
ENSG00000142168 SOD1 NonAssociatedWithProgression
ENSG00000112096 SOD2 o++b
ENSG00000197912 SPG7 o-o
ENSG00000136143 SUCLA2 -+o
ENSG00000163541 SUCLG1 o-o
ENSG00000156502 SUPV3L1 o--a
ENSG00000148290 SURF1 o--a
ENSG00000136270 TBRG4 o--a
ENSG00000108064 TFAM NonAssociatedWithProgression
ENSG00000162851 TFB2M NonAssociatedWithProgression
ENSG00000113272 THG1L -oo
ENSG00000134809 TIMM10 o-o
ENSG00000099800 TIMM13 o--a
ENSG00000134375 TIMM17A -oo
ENSG00000126768 TIMM17B --o
ENSG00000138297 TIMM23 o--a
ENSG00000104980 TIMM44 ---
ENSG00000105197 TIMM50 ---
ENSG00000150779 TIMM8B --o
ENSG00000100575 TIMM9 -+o
ENSG00000184857 TMEM186 NonAssociatedWithProgression
ENSG00000100216 TOMM22 o--b
ENSG00000025772 TOMM34 o--a
ENSG00000141510 TP53 o--a
ENSG00000182606 TRAK1 oo+
ENSG00000170855 TRIAP1 o--b
ENSG00000100416 TRMU ---
ENSG00000072756 TRNT1 o++a
ENSG00000123297 TSFM o+-
ENSG00000178952 TUFM o--a
ENSG00000184470 TXNRD2 --o
ENSG00000175564 UCP3 NonAssociatedWithProgression
ENSG00000156467 UQCRB o++b
ENSG00000010256 UQCRC1 o--a
ENSG00000173660 UQCRH NonAssociatedWithProgression
ENSG00000213585 VDAC1 --o
ENSG00000165637 VDAC2 -o-
ENSG00000078668 VDAC3 -+o