GeneSet KEGG_PURINE_METABOLISM (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-+o -3.3 0.02028 72.0 10.0 3.36
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000196839 ADA -o-
ENSG00000138031 ADCY3 o-o
ENSG00000121281 ADCY7 -+o
ENSG00000156110 ADK -+o
ENSG00000239900 ADSL -+o
ENSG00000035687 ADSS NonAssociatedWithProgression
ENSG00000185100 ADSSL1 NonAssociatedWithProgression
ENSG00000106992 AK1 NonAssociatedWithProgression
ENSG00000004455 AK2 o--a
ENSG00000116337 AMPD2 NonAssociatedWithProgression
ENSG00000198931 APRT o--b
ENSG00000138363 ATIC o--b
ENSG00000170222 C17orf48 o-+
ENSG00000171302 CANT1 o--b
ENSG00000156136 DCK ---
ENSG00000114956 DGUOK NonAssociatedWithProgression
ENSG00000197217 ENTPD4 NonAssociatedWithProgression
ENSG00000197586 ENTPD6 o-o
ENSG00000159131 GART NonAssociatedWithProgression
ENSG00000100938 GMPR2 -+o
ENSG00000163655 GMPS o--a
ENSG00000061918 GUCY1B3 -+o
ENSG00000143774 GUK1 o--a
ENSG00000165704 HPRT1 NonAssociatedWithProgression
ENSG00000106348 IMPDH1 o--a
ENSG00000178035 IMPDH2 o-o
ENSG00000125877 ITPA NonAssociatedWithProgression
ENSG00000239672 NME1 o--a
ENSG00000243678 NME1-NME2 NonAssociatedWithProgression
ENSG00000011052 NME2 NonAssociatedWithProgression
ENSG00000103202 NME4 --o
ENSG00000143156 NME7 o+o
ENSG00000159899 NPR2 ---
ENSG00000125458 NT5C o-o
ENSG00000076685 NT5C2 o--b
ENSG00000122643 NT5C3 NonAssociatedWithProgression
ENSG00000164978 NUDT2 o-+
ENSG00000165609 NUDT5 --o
ENSG00000170502 NUDT9 o+-
ENSG00000128050 PAICS NonAssociatedWithProgression
ENSG00000138801 PAPSS1 -+o
ENSG00000112541 PDE10A o++b
ENSG00000123360 PDE1B o-+
ENSG00000065989 PDE4A ---
ENSG00000138735 PDE5A o++a
ENSG00000156973 PDE6D NonAssociatedWithProgression
ENSG00000205268 PDE7A ---
ENSG00000073417 PDE8A o++a
ENSG00000178921 PFAS ---
ENSG00000143627 PKLR NonAssociatedWithProgression
ENSG00000067225 PKM2 o--b
ENSG00000198805 PNP o--a
ENSG00000138035 PNPT1 o+-
ENSG00000101868 POLA1 NonAssociatedWithProgression
ENSG00000014138 POLA2 o++b
ENSG00000062822 POLD1 o--a
ENSG00000106628 POLD2 o--b
ENSG00000077514 POLD3 o+o
ENSG00000175482 POLD4 --o
ENSG00000177084 POLE o--b
ENSG00000100479 POLE2 -o-
ENSG00000148229 POLE3 o--a
ENSG00000068654 POLR1A NonAssociatedWithProgression
ENSG00000125630 POLR1B oo-
ENSG00000186184 POLR1D o--a
ENSG00000137054 POLR1E o--b
ENSG00000181222 POLR2A ---
ENSG00000047315 POLR2B +oo
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000144231 POLR2D o--b
ENSG00000100142 POLR2F NonAssociatedWithProgression
ENSG00000168002 POLR2G NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000105258 POLR2I --o
ENSG00000005075 POLR2J ---
ENSG00000228049 POLR2J2 o--a
ENSG00000177700 POLR2L o-o
ENSG00000148606 POLR3A NonAssociatedWithProgression
ENSG00000013503 POLR3B -+o
ENSG00000186141 POLR3C ---
ENSG00000168495 POLR3D -+o
ENSG00000132664 POLR3F o-o
ENSG00000113356 POLR3G -+o
ENSG00000121851 POLR3GL NonAssociatedWithProgression
ENSG00000100413 POLR3H o--a
ENSG00000161980 POLR3K -oo
ENSG00000128059 PPAT NonAssociatedWithProgression
ENSG00000198056 PRIM1 ---
ENSG00000146143 PRIM2 o-+
ENSG00000147224 PRPS1 o--a
ENSG00000101911 PRPS2 ---
ENSG00000143363 PRUNE +o+
ENSG00000167325 RRM1 o--a
ENSG00000171848 RRM2 o--a
ENSG00000048392 RRM2B -+o
ENSG00000066379 ZNRD1 NonAssociatedWithProgression