PEACHi
GeneSet KEGG_CELL_CYCLE (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.7 0.0349 74.0 19.0 10.22
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000097007 ABL1 o--a
ENSG00000153107 ANAPC1 o--a
ENSG00000164162 ANAPC10 o++b
ENSG00000141552 ANAPC11 NonAssociatedWithProgression
ENSG00000129055 ANAPC13 o++b
ENSG00000176248 ANAPC2 NonAssociatedWithProgression
ENSG00000053900 ANAPC4 NonAssociatedWithProgression
ENSG00000089053 ANAPC5 o++a
ENSG00000196510 ANAPC7 o++b
ENSG00000149311 ATM NonAssociatedWithProgression
ENSG00000175054 ATR NonAssociatedWithProgression
ENSG00000169679 BUB1 -o-
ENSG00000156970 BUB1B +oo
ENSG00000154473 BUB3 o--a
ENSG00000145386 CCNA2 o--b
ENSG00000134057 CCNB1 oo-
ENSG00000157456 CCNB2 oo-
ENSG00000112576 CCND3 o--b
ENSG00000105173 CCNE1 o--b
ENSG00000175305 CCNE2 NonAssociatedWithProgression
ENSG00000134480 CCNH -o-
ENSG00000079335 CDC14A o+o
ENSG00000130177 CDC16 NonAssociatedWithProgression
ENSG00000094880 CDC23 NonAssociatedWithProgression
ENSG00000164045 CDC25A o--b
ENSG00000101224 CDC25B o--a
ENSG00000158402 CDC25C o-+
ENSG00000176386 CDC26 NonAssociatedWithProgression
ENSG00000004897 CDC27 NonAssociatedWithProgression
ENSG00000093009 CDC45 o++b
ENSG00000094804 CDC6 NonAssociatedWithProgression
ENSG00000097046 CDC7 NonAssociatedWithProgression
ENSG00000170312 CDK1 o-+
ENSG00000123374 CDK2 oo-
ENSG00000135446 CDK4 o--a
ENSG00000105810 CDK6 o--a
ENSG00000134058 CDK7 o+o
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000123080 CDKN2C o-o
ENSG00000149554 CHEK1 o+o
ENSG00000183765 CHEK2 ---
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000055130 CUL1 o++a
ENSG00000006634 DBF4 ---
ENSG00000101412 E2F1 o--b
ENSG00000007968 E2F2 o--a
ENSG00000112242 E2F3 NonAssociatedWithProgression
ENSG00000205250 E2F4 ---
ENSG00000133740 E2F5 o--b
ENSG00000100393 EP300 o++b
ENSG00000135476 ESPL1 o-+
ENSG00000116717 GADD45A o+o
ENSG00000099860 GADD45B o--b
ENSG00000082701 GSK3B -o-
ENSG00000116478 HDAC1 ---
ENSG00000196591 HDAC2 NonAssociatedWithProgression
ENSG00000002822 MAD1L1 o-o
ENSG00000164109 MAD2L1 NonAssociatedWithProgression
ENSG00000116670 MAD2L2 o--a
ENSG00000073111 MCM2 o--a
ENSG00000104738 MCM4 o--a
ENSG00000100297 MCM5 o--b
ENSG00000076003 MCM6 o--a
ENSG00000166508 MCM7 o--b
ENSG00000135679 MDM2 -o-
ENSG00000136997 MYC o--b
ENSG00000132646 PCNA -o-
ENSG00000127564 PKMYT1 +-o
ENSG00000166851 PLK1 o--a
ENSG00000253729 PRKDC o--b
ENSG00000164611 PTTG1 NonAssociatedWithProgression
ENSG00000164754 RAD21 o--b
ENSG00000139687 RB1 NonAssociatedWithProgression
ENSG00000080839 RBL1 +o+
ENSG00000103479 RBL2 NonAssociatedWithProgression
ENSG00000100387 RBX1 o--a
ENSG00000113558 SKP1 ---
ENSG00000145604 SKP2 o++b
ENSG00000175387 SMAD2 NonAssociatedWithProgression
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000141646 SMAD4 o--b
ENSG00000072501 SMC1A o--a
ENSG00000108055 SMC3 NonAssociatedWithProgression
ENSG00000118007 STAG1 NonAssociatedWithProgression
ENSG00000101972 STAG2 o--b
ENSG00000198176 TFDP1 -o-
ENSG00000114126 TFDP2 o--b
ENSG00000105329 TGFB1 o--a
ENSG00000141510 TP53 o--a
ENSG00000112742 TTK o--b
ENSG00000166483 WEE1 NonAssociatedWithProgression
ENSG00000166913 YWHAB o--b
ENSG00000108953 YWHAE NonAssociatedWithProgression
ENSG00000170027 YWHAG o+-
ENSG00000128245 YWHAH +-o
ENSG00000134308 YWHAQ o+-
ENSG00000164924 YWHAZ o--b
ENSG00000116809 ZBTB17 o--b