PEACHi
GeneSet HYDROLASE_ACTIVITY_ACTING_ON_ESTER_BONDS (GO_-_Molecular_Function.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
+oo -3.2 0.03238 103.0 7.0 1.93
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000101473 ACOT8 ---
ENSG00000143727 ACP1 +oo
ENSG00000134575 ACP2 NonAssociatedWithProgression
ENSG00000162836 ACP6 o-+
ENSG00000214274 ANG o++b
ENSG00000100823 APEX1 NonAssociatedWithProgression
ENSG00000137074 APTX NonAssociatedWithProgression
ENSG00000100299 ARSA ---
ENSG00000113273 ARSB -+o
ENSG00000141337 ARSG o++a
ENSG00000164291 ARSK -+o
ENSG00000101224 CDC25B o--a
ENSG00000100526 CDKN3 NonAssociatedWithProgression
ENSG00000172831 CES2 ---
ENSG00000173786 CNP ---
ENSG00000060069 CTDP1 ---
ENSG00000172115 CYCS o--b
ENSG00000138231 DBR1 o--b
ENSG00000160049 DFFA NonAssociatedWithProgression
ENSG00000100697 DICER1 NonAssociatedWithProgression
ENSG00000075711 DLG1 NonAssociatedWithProgression
ENSG00000013563 DNASE1L1 o-o
ENSG00000167968 DNASE1L2 o--a
ENSG00000105612 DNASE2 NonAssociatedWithProgression
ENSG00000120129 DUSP1 o--a
ENSG00000144048 DUSP11 o--b
ENSG00000081721 DUSP12 NonAssociatedWithProgression
ENSG00000158050 DUSP2 o--b
ENSG00000108861 DUSP3 o-+
ENSG00000120875 DUSP4 ---
ENSG00000138166 DUSP5 +-o
ENSG00000139318 DUSP6 NonAssociatedWithProgression
ENSG00000164086 DUSP7 o--a
ENSG00000184545 DUSP8 ---
ENSG00000112425 EPM2A +oo
ENSG00000175595 ERCC4 o-o
ENSG00000134899 ERCC5 NonAssociatedWithProgression
ENSG00000174371 EXO1 o++b
ENSG00000130713 EXOSC2 o--b
ENSG00000075914 EXOSC7 NonAssociatedWithProgression
ENSG00000168496 FEN1 NonAssociatedWithProgression
ENSG00000135677 GNS o-o
ENSG00000063854 HAGH o--a
ENSG00000198130 HIBCH o++b
ENSG00000010404 IDS +oo
ENSG00000133731 IMPA1 o+o
ENSG00000141401 IMPA2 o--b
ENSG00000168918 INPP5D -oo
ENSG00000148384 INPP5E o-+
ENSG00000182866 LCK o-o
ENSG00000120992 LYPLA1 o+-
ENSG00000130479 MAP1S o--a
ENSG00000129071 MBD4 o+o
ENSG00000107789 MINPP1 NonAssociatedWithProgression
ENSG00000163719 MTMR14 o-+
ENSG00000087053 MTMR2 o+o
ENSG00000100330 MTMR3 NonAssociatedWithProgression
ENSG00000078177 N4BP2 NonAssociatedWithProgression
ENSG00000239672 NME1 o--a
ENSG00000125458 NT5C o-o
ENSG00000076685 NT5C2 o--b
ENSG00000122643 NT5C3 NonAssociatedWithProgression
ENSG00000065057 NTHL1 --o
ENSG00000122126 OCRL o++a
ENSG00000114026 OGG1 o--a
ENSG00000112541 PDE10A o++b
ENSG00000123360 PDE1B o-+
ENSG00000065989 PDE4A ---
ENSG00000205268 PDE7A ---
ENSG00000167004 PDIA3 o--a
ENSG00000197121 PGAP1 NonAssociatedWithProgression
ENSG00000184381 PLA2G6 ---
ENSG00000137841 PLCB2 o-+
ENSG00000114805 PLCH1 o+o
ENSG00000105223 PLD3 ---
ENSG00000135241 PNPLA8 NonAssociatedWithProgression
ENSG00000105854 PON2 o++a
ENSG00000104356 POP1 o+o
ENSG00000105171 POP4 NonAssociatedWithProgression
ENSG00000172336 POP7 o--a
ENSG00000067113 PPAP2A o+-
ENSG00000162407 PPAP2B NonAssociatedWithProgression
ENSG00000086717 PPEF1 +o+
ENSG00000100614 PPM1A o--a
ENSG00000138032 PPM1B o-o
ENSG00000115241 PPM1G o--a
ENSG00000164088 PPM1M ---
ENSG00000214517 PPME1 o--b
ENSG00000172531 PPP1CA o--a
ENSG00000117751 PPP1R8 NonAssociatedWithProgression
ENSG00000104695 PPP2CB +o+
ENSG00000221914 PPP2R2A o--b
ENSG00000167393 PPP2R3B o--a
ENSG00000011485 PPP5C o--a
ENSG00000119414 PPP6C o--b
ENSG00000131238 PPT1 +-o
ENSG00000117592 PRDX6 NonAssociatedWithProgression
ENSG00000146733 PSPH ---
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000184007 PTP4A2 o--a
ENSG00000165996 PTPLA +o+
ENSG00000196396 PTPN1 +oo
ENSG00000179295 PTPN11 NonAssociatedWithProgression
ENSG00000127947 PTPN12 +oo
ENSG00000175354 PTPN2 NonAssociatedWithProgression
ENSG00000134242 PTPN22 o++b
ENSG00000070159 PTPN3 NonAssociatedWithProgression
ENSG00000088179 PTPN4 o++b
ENSG00000143851 PTPN7 o--b
ENSG00000132670 PTPRA o--a
ENSG00000081237 PTPRC o+o
ENSG00000153707 PTPRD NonAssociatedWithProgression
ENSG00000132334 PTPRE +oo
ENSG00000142949 PTPRF ---
ENSG00000144724 PTPRG NonAssociatedWithProgression
ENSG00000152894 PTPRK NonAssociatedWithProgression
ENSG00000173482 PTPRM NonAssociatedWithProgression
ENSG00000155093 PTPRN2 -+o
ENSG00000113456 RAD1 NonAssociatedWithProgression
ENSG00000113522 RAD50 NonAssociatedWithProgression
ENSG00000172613 RAD9A o--b
ENSG00000076043 REXO2 o++b
ENSG00000169413 RNASE6 NonAssociatedWithProgression
ENSG00000171865 RNASEH1 o--b
ENSG00000104889 RNASEH2A o--b
ENSG00000148688 RPP30 NonAssociatedWithProgression
ENSG00000152464 RPP38 o+o
ENSG00000124787 RPP40 NonAssociatedWithProgression
ENSG00000100241 SBF1 ---
ENSG00000166311 SMPD1 o-+
ENSG00000159082 SYNJ1 NonAssociatedWithProgression
ENSG00000105197 TIMM50 ---
ENSG00000141510 TP53 o--a
ENSG00000213689 TREX1 o--b
ENSG00000118939 UCHL3 NonAssociatedWithProgression
ENSG00000152484 USP12 o--b
ENSG00000143258 USP21 -o-
ENSG00000111667 USP5 ---
ENSG00000145390 USP53 o++b
ENSG00000165392 WRN +oo
ENSG00000088930 XRN2 NonAssociatedWithProgression
ENSG00000180667 YOD1 o--b