PEACHi
GeneSet HIV_Schoggins_et_al_2011 (HIV_Collection.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++b -2.4 0.04139 115.0 17.0 9.2
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000166016 ABTB2 NonAssociatedWithProgression
ENSG00000160710 ADAR o--a
ENSG00000148926 ADM +oo
ENSG00000117020 AKT3 o++b
ENSG00000081181 ARG2 NonAssociatedWithProgression
ENSG00000163947 ARHGEF3 NonAssociatedWithProgression
ENSG00000133794 ARNTL NonAssociatedWithProgression
ENSG00000162772 ATF3 +-o
ENSG00000158470 B4GALT5 o++b
ENSG00000069399 BCL3 NonAssociatedWithProgression
ENSG00000100220 C22orf28 NonAssociatedWithProgression
ENSG00000174749 C4orf32 o++a
ENSG00000151470 C4orf33 o++b
ENSG00000157693 C9orf91 o-+
ENSG00000165806 CASP7 o-o
ENSG00000005059 CCDC109B o++b
ENSG00000152133 CCDC75 o+o
ENSG00000119242 CCDC92 ---
ENSG00000112576 CCND3 o--b
ENSG00000004468 CD38 -+o
ENSG00000010278 CD9 o-o
ENSG00000124762 CDKN1A oo-
ENSG00000086065 CHMP5 o++b
ENSG00000110852 CLEC2B NonAssociatedWithProgression
ENSG00000168405 CMAH o--a
ENSG00000148444 COMMD3 -+o
ENSG00000110090 CPT1A --o
ENSG00000008405 CRY1 NonAssociatedWithProgression
ENSG00000060138 CSDA -o-
ENSG00000168209 DDIT4 o+-
ENSG00000215301 DDX3X oo-
ENSG00000163840 DTX3L oo+
ENSG00000138166 DUSP5 +-o
ENSG00000146425 DYNLT1 NonAssociatedWithProgression
ENSG00000100129 EIF3L o-o
ENSG00000120690 ELF1 o--b
ENSG00000107566 ERLIN1 o-o
ENSG00000139083 ETV6 o++a
ENSG00000196814 FAM125B o--a
ENSG00000125355 FAM70A oo+
ENSG00000096060 FKBP5 o--b
ENSG00000196371 FUT4 NonAssociatedWithProgression
ENSG00000178950 GAK o--a
ENSG00000143641 GALNT2 o--a
ENSG00000115271 GCA --o
ENSG00000131979 GCH1 +o+
ENSG00000198814 GK -oo
ENSG00000100226 GTPBP1 o--a
ENSG00000172432 GTPBP2 o--a
ENSG00000173706 HEG1 NonAssociatedWithProgression
ENSG00000188290 HES4 o--b
ENSG00000163666 HESX1 o++b
ENSG00000159399 HK2 o--b
ENSG00000204525 HLA-C o-+
ENSG00000204592 HLA-E +-o
ENSG00000163565 IFI16 o--a
ENSG00000216490 IFI30 oo+
ENSG00000137965 IFI44 o+o
ENSG00000126709 IFI6 oo+
ENSG00000027697 IFNGR1 NonAssociatedWithProgression
ENSG00000115457 IGFBP2 o--b
ENSG00000141401 IMPA2 o--b
ENSG00000125347 IRF1 o+o
ENSG00000168310 IRF2 o++b
ENSG00000185507 IRF7 ---
ENSG00000213928 IRF9 NonAssociatedWithProgression
ENSG00000187608 ISG15 o-+
ENSG00000171223 JUNB ---
ENSG00000002549 LAP3 -+o
ENSG00000116678 LEPR NonAssociatedWithProgression
ENSG00000100600 LGMN +-o
ENSG00000107798 LIPA NonAssociatedWithProgression
ENSG00000160932 LY6E o--b
ENSG00000197442 MAP3K5 o++a
ENSG00000155130 MARCKS +-o
ENSG00000125952 MAX NonAssociatedWithProgression
ENSG00000143384 MCL1 o-o
ENSG00000204516 MICB o-o
ENSG00000163738 MTHFD2L o+o
ENSG00000183486 MX2 NonAssociatedWithProgression
ENSG00000172936 MYD88 +o+
ENSG00000080986 NDC80 o++b
ENSG00000165030 NFIL3 -+o
ENSG00000123609 NMI -+o
ENSG00000170485 NPAS2 o-+
ENSG00000124785 NRN1 o--b
ENSG00000122643 NT5C3 NonAssociatedWithProgression
ENSG00000093000 NUP50 NonAssociatedWithProgression
ENSG00000060491 OGFR o--b
ENSG00000123240 OPTN +o+
ENSG00000090621 PABPC4 o--a
ENSG00000059378 PARP12 o++a
ENSG00000152256 PDK1 NonAssociatedWithProgression
ENSG00000170525 PFKFB3 o--a
ENSG00000136147 PHF11 o++b
ENSG00000043143 PHF15 o--b
ENSG00000038210 PI4K2B o-+
ENSG00000198355 PIM3 o--a
ENSG00000188313 PLSCR1 o++b
ENSG00000141682 PMAIP1 oo-
ENSG00000140464 PML o-o
ENSG00000140650 PMM2 o--b
ENSG00000138035 PNPT1 o+-
ENSG00000163644 PPM1K -+o
ENSG00000204264 PSMB8 o--b
ENSG00000240065 PSMB9 o-o
ENSG00000187514 PTMA o--b
ENSG00000177192 PUS1 NonAssociatedWithProgression
ENSG00000168297 PXK o+o
ENSG00000069974 RAB27A o++b
ENSG00000125826 RBCK1 o--a
ENSG00000090104 RGS1 o++b
ENSG00000104312 RIPK2 o++b
ENSG00000116514 RNF19B o++b
ENSG00000116251 RPL22 +-o
ENSG00000138760 SCARB2 o++b
ENSG00000170542 SERPINB9 o++b
ENSG00000106366 SERPINE1 o+-
ENSG00000155380 SLC16A1 o--b
ENSG00000155287 SLC25A28 o--b
ENSG00000174032 SLC25A30 +o+
ENSG00000166750 SLFN5 NonAssociatedWithProgression
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000185338 SOCS1 o--a
ENSG00000135899 SP110 NonAssociatedWithProgression
ENSG00000171621 SPSB1 o--a
ENSG00000104549 SQLE +oo
ENSG00000157216 SSBP3 o--a
ENSG00000172345 STARD5 -+o
ENSG00000115415 STAT1 oo+
ENSG00000168610 STAT3 o--b
ENSG00000164691 TAGAP +oo
ENSG00000183684 THOC4 -o-
ENSG00000102265 TIMP1 o--a
ENSG00000062716 TMEM49 o-+
ENSG00000118503 TNFAIP3 o--a
ENSG00000135148 TRAFD1 NonAssociatedWithProgression
ENSG00000213689 TREX1 o--b
ENSG00000106785 TRIM14 NonAssociatedWithProgression
ENSG00000132109 TRIM21 NonAssociatedWithProgression
ENSG00000121060 TRIM25 NonAssociatedWithProgression
ENSG00000132256 TRIM5 o++b
ENSG00000156587 UBE2L6 oo+
ENSG00000140105 WARS NonAssociatedWithProgression