PEACHi
GeneSet CELL_CYCLE_GO_0007049 (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -3.5 0.02938 169.0 40.0 24.0
DownRegulated -2.9 0.03039 169.0 118.0 99.8
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000097007 ABL1 o--a
ENSG00000169129 AFAP1L2 NonAssociatedWithProgression
ENSG00000204472 AIF1 o--a
ENSG00000105127 AKAP8 NonAssociatedWithProgression
ENSG00000164162 ANAPC10 o++b
ENSG00000141552 ANAPC11 NonAssociatedWithProgression
ENSG00000176248 ANAPC2 NonAssociatedWithProgression
ENSG00000053900 ANAPC4 NonAssociatedWithProgression
ENSG00000089053 ANAPC5 o++a
ENSG00000011426 ANLN NonAssociatedWithProgression
ENSG00000166313 APBB1 o-o
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000149311 ATM NonAssociatedWithProgression
ENSG00000175054 ATR NonAssociatedWithProgression
ENSG00000164053 ATRIP NonAssociatedWithProgression
ENSG00000087586 AURKA +-o
ENSG00000060982 BCAT1 +-o
ENSG00000107949 BCCIP -+o
ENSG00000089685 BIRC5 ---
ENSG00000125378 BMP4 +-o
ENSG00000154640 BTG3 NonAssociatedWithProgression
ENSG00000169679 BUB1 -o-
ENSG00000156970 BUB1B +oo
ENSG00000102760 C13orf15 NonAssociatedWithProgression
ENSG00000145386 CCNA2 o--b
ENSG00000112576 CCND3 o--b
ENSG00000175305 CCNE2 NonAssociatedWithProgression
ENSG00000113328 CCNG1 +o+
ENSG00000138764 CCNG2 ---
ENSG00000090061 CCNK +-o
ENSG00000082258 CCNT2 o-o
ENSG00000178562 CD28 o+o
ENSG00000151465 CDC123 NonAssociatedWithProgression
ENSG00000130177 CDC16 NonAssociatedWithProgression
ENSG00000094880 CDC23 NonAssociatedWithProgression
ENSG00000164045 CDC25A o--b
ENSG00000101224 CDC25B o--a
ENSG00000158402 CDC25C o-+
ENSG00000004897 CDC27 NonAssociatedWithProgression
ENSG00000105401 CDC37 ---
ENSG00000094804 CDC6 NonAssociatedWithProgression
ENSG00000097046 CDC7 NonAssociatedWithProgression
ENSG00000146670 CDCA5 o--b
ENSG00000185324 CDK10 o--a
ENSG00000123374 CDK2 oo-
ENSG00000111328 CDK2AP1 --o
ENSG00000135446 CDK4 o--a
ENSG00000176749 CDK5R1 NonAssociatedWithProgression
ENSG00000101391 CDK5RAP1 o--a
ENSG00000108465 CDK5RAP3 NonAssociatedWithProgression
ENSG00000105810 CDK6 o--a
ENSG00000134058 CDK7 o+o
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000123080 CDKN2C o-o
ENSG00000100526 CDKN3 NonAssociatedWithProgression
ENSG00000138778 CENPE NonAssociatedWithProgression
ENSG00000117724 CENPF o--a
ENSG00000126001 CEP250 o-o
ENSG00000153140 CETN3 oo+
ENSG00000149554 CHEK1 o+o
ENSG00000183765 CHEK2 ---
ENSG00000072609 CHFR o-o
ENSG00000131165 CHMP1A o--a
ENSG00000122966 CIT +-o
ENSG00000164442 CITED2 o++b
ENSG00000175216 CKAP5 NonAssociatedWithProgression
ENSG00000173207 CKS1B NonAssociatedWithProgression
ENSG00000123975 CKS2 o--a
ENSG00000130779 CLIP1 o+o
ENSG00000170037 CNTROB o-o
ENSG00000055130 CUL1 o++a
ENSG00000108094 CUL2 o+o
ENSG00000036257 CUL3 o--a
ENSG00000139842 CUL4A oo-
ENSG00000166266 CUL5 o--b
ENSG00000006634 DBF4 ---
ENSG00000175203 DCTN2 --o
ENSG00000167986 DDB1 o--a
ENSG00000013573 DDX11 o--a
ENSG00000100867 DHRS2 NonAssociatedWithProgression
ENSG00000075711 DLG1 NonAssociatedWithProgression
ENSG00000168393 DTYMK o-o
ENSG00000101412 E2F1 o--b
ENSG00000110321 EIF4G2 o+-
ENSG00000104884 ERCC2 ---
ENSG00000163161 ERCC3 o-o
ENSG00000135476 ESPL1 o-+
ENSG00000112029 FBXO5 NonAssociatedWithProgression
ENSG00000053254 FOXN3 oo+
ENSG00000184481 FOXO4 --o
ENSG00000116717 GADD45A o+o
ENSG00000180447 GAS1 o++b
ENSG00000007237 GAS7 ---
ENSG00000162676 GFI1 o-o
ENSG00000104499 GML o++b
ENSG00000112312 GMNN NonAssociatedWithProgression
ENSG00000169727 GPS1 ---
ENSG00000132522 GPS2 ---
ENSG00000103342 GSPT1 NonAssociatedWithProgression
ENSG00000110768 GTF2H1 o++b
ENSG00000107937 GTPBP4 o--b
ENSG00000172534 HCFC1 o--b
ENSG00000138646 HERC5 +-o
ENSG00000186834 HEXIM1 o--a
ENSG00000168517 HEXIM2 NonAssociatedWithProgression
ENSG00000136273 HUS1 o+o
ENSG00000111653 ING4 o+-
ENSG00000152409 JMY o--a
ENSG00000186625 KATNA1 NonAssociatedWithProgression
ENSG00000121774 KHDRBS1 NonAssociatedWithProgression
ENSG00000138160 KIF11 o+-
ENSG00000163808 KIF15 NonAssociatedWithProgression
ENSG00000079616 KIF22 o--b
ENSG00000137807 KIF23 o--a
ENSG00000142945 KIF2C o--b
ENSG00000184445 KNTC1 o+o
ENSG00000182481 KPNA2 o--a
ENSG00000150457 LATS2 o++a
ENSG00000005156 LIG3 NonAssociatedWithProgression
ENSG00000164109 MAD2L1 NonAssociatedWithProgression
ENSG00000116670 MAD2L2 o--a
ENSG00000110514 MADD o--b
ENSG00000173327 MAP3K11 ---
ENSG00000073111 MCM2 o--a
ENSG00000198625 MDM4 o-o
ENSG00000116688 MFN2 o--b
ENSG00000135698 MPHOSPH6 -+o
ENSG00000051825 MPHOSPH9 o--b
ENSG00000204410 MSH5 NonAssociatedWithProgression
ENSG00000136997 MYC o--b
ENSG00000133026 MYH10 o--a
ENSG00000159593 NAE1 o+o
ENSG00000132780 NASP o--a
ENSG00000104320 NBN NonAssociatedWithProgression
ENSG00000121152 NCAPH o--a
ENSG00000080986 NDC80 o++b
ENSG00000072864 NDE1 --o
ENSG00000117650 NEK2 o--b
ENSG00000166197 NOLC1 o--b
ENSG00000134250 NOTCH2 o-o
ENSG00000181163 NPM1 o--b
ENSG00000137497 NUMA1 o--b
ENSG00000137804 NUSAP1 NonAssociatedWithProgression
ENSG00000170515 PA2G4 NonAssociatedWithProgression
ENSG00000007168 PAFAH1B1 o+-
ENSG00000145730 PAM oo+
ENSG00000163939 PBRM1 NonAssociatedWithProgression
ENSG00000090097 PCBP4 o-o
ENSG00000083642 PDS5B NonAssociatedWithProgression
ENSG00000113068 PFDN1 o-o
ENSG00000102096 PIM2 NonAssociatedWithProgression
ENSG00000127445 PIN1 o-o
ENSG00000127564 PKMYT1 +-o
ENSG00000118495 PLAGL1 NonAssociatedWithProgression
ENSG00000166851 PLK1 o--a
ENSG00000140464 PML o-o
ENSG00000101868 POLA1 NonAssociatedWithProgression
ENSG00000062822 POLD1 o--a
ENSG00000177084 POLE o--b
ENSG00000115241 PPM1G o--a
ENSG00000087074 PPP1R15A ---
ENSG00000108819 PPP1R9B -+o
ENSG00000167393 PPP2R3B o--a
ENSG00000011485 PPP5C o--a
ENSG00000119414 PPP6C o--b
ENSG00000198901 PRC1 +-o
ENSG00000100462 PRMT5 o--a
ENSG00000106772 PRUNE2 o++a
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000081237 PTPRC o+o
ENSG00000011454 RABGAP1 o--a
ENSG00000161800 RACGAP1 o-+
ENSG00000113456 RAD1 NonAssociatedWithProgression
ENSG00000152942 RAD17 o--a
ENSG00000164754 RAD21 o--b
ENSG00000113522 RAD50 NonAssociatedWithProgression
ENSG00000051180 RAD51 NonAssociatedWithProgression
ENSG00000182185 RAD51L1 ---
ENSG00000185379 RAD51L3 o--b
ENSG00000197275 RAD54B NonAssociatedWithProgression
ENSG00000085999 RAD54L NonAssociatedWithProgression
ENSG00000172613 RAD9A o--b
ENSG00000132341 RAN o--b
ENSG00000068028 RASSF1 o--a
ENSG00000139687 RB1 NonAssociatedWithProgression
ENSG00000101773 RBBP8 NonAssociatedWithProgression
ENSG00000180198 RCC1 o--a
ENSG00000143878 RHOB +-o
ENSG00000135249 RINT1 o--b
ENSG00000020633 RUNX3 o--b
ENSG00000168061 SAC3D1 NonAssociatedWithProgression
ENSG00000156876 SASS6 o++b
ENSG00000197019 SERTAD1 ---
ENSG00000145604 SKP2 o++b
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000072501 SMC1A o--a
ENSG00000108055 SMC3 NonAssociatedWithProgression
ENSG00000113810 SMC4 o+-
ENSG00000173465 SSSCA1 NonAssociatedWithProgression
ENSG00000066923 STAG3 o--b
ENSG00000118046 STK11 o--a
ENSG00000117632 STMN1 o--b
ENSG00000196792 STRN3 o+o
ENSG00000165416 SUGT1 -+o
ENSG00000147133 TAF1 NonAssociatedWithProgression
ENSG00000120948 TARDBP o--a
ENSG00000154144 TBRG1 o--b
ENSG00000136270 TBRG4 o--a
ENSG00000105329 TGFB1 o--a
ENSG00000075131 TIPIN NonAssociatedWithProgression
ENSG00000177302 TOP3A o--a
ENSG00000141510 TP53 o--a
ENSG00000143514 TP53BP2 oo-
ENSG00000088325 TPX2 o--b
ENSG00000170855 TRIAP1 o--b
ENSG00000112742 TTK o--b
ENSG00000074935 TUBE1 o+o
ENSG00000131462 TUBG1 --o
ENSG00000170315 UBB ---
ENSG00000175063 UBE2C o-o
ENSG00000152332 UHMK1 o--a
ENSG00000147854 UHRF2 o-o
ENSG00000005007 UPF1 o--b
ENSG00000156256 USP16 NonAssociatedWithProgression
ENSG00000154767 XPC o--b
ENSG00000196584 XRCC2 ---
ENSG00000116809 ZBTB17 o--b
ENSG00000086827 ZW10 NonAssociatedWithProgression
ENSG00000122952 ZWINT o-o