| ENSG00000142208 |
AKT1 |
---
|
| ENSG00000105221 |
AKT2 |
o--a
|
| ENSG00000117020 |
AKT3 |
o++b
|
| ENSG00000178562 |
CD28 |
o+o
|
| ENSG00000070831 |
CDC42 |
+oo
|
| ENSG00000010810 |
FYN |
+oo
|
| ENSG00000100351 |
GRAP2 |
---
|
| ENSG00000177885 |
GRB2 |
NonAssociatedWithProgression
|
| ENSG00000182866 |
LCK |
o-o
|
| ENSG00000006062 |
MAP3K14 |
---
|
| ENSG00000107968 |
MAP3K8 |
o++a
|
| ENSG00000119487 |
MAPKAP1 |
o--a
|
| ENSG00000167965 |
MLST8 |
o--a
|
| ENSG00000198793 |
MTOR |
NonAssociatedWithProgression
|
| ENSG00000149269 |
PAK1 |
oo+
|
| ENSG00000180370 |
PAK2 |
---
|
| ENSG00000140992 |
PDPK1 |
-o-
|
| ENSG00000121879 |
PIK3CA |
+-o
|
| ENSG00000145675 |
PIK3R1 |
o--a
|
| ENSG00000105647 |
PIK3R2 |
o--a
|
| ENSG00000117461 |
PIK3R3 |
NonAssociatedWithProgression
|
| ENSG00000136238 |
RAC1 |
NonAssociatedWithProgression
|
| ENSG00000164327 |
RICTOR |
o--b
|
| ENSG00000101255 |
TRIB3 |
+-o
|
| ENSG00000141968 |
VAV1 |
o--a
|
| ENSG00000176105 |
YES1 |
+-o
|
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at
three phases of the viral life cycle, namely reverse transcription, integration, and late phase.
Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering.
Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).