PEACHi
GeneSet Signaling by NOTCH (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
AllGenesAssociatedWithProgression -2.6 0.03147 76.0 65.0 55.37
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000137845 ADAM10 NonAssociatedWithProgression
ENSG00000151694 ADAM17 +-o
ENSG00000117362 APH1A o--a
ENSG00000138613 APH1B o++b
ENSG00000141480 ARRB2 ---
ENSG00000174437 ATP2A2 -o-
ENSG00000074370 ATP2A3 o--b
ENSG00000086062 B4GALT1 ---
ENSG00000112237 CCNC o--a
ENSG00000132964 CDK8 o+o
ENSG00000005339 CREBBP NonAssociatedWithProgression
ENSG00000055130 CUL1 o++a
ENSG00000135144 DTX1 o--b
ENSG00000091073 DTX2 ---
ENSG00000092847 EIF2C1 -+o
ENSG00000123908 EIF2C2 o--b
ENSG00000126070 EIF2C3 o+o
ENSG00000134698 EIF2C4 +o+
ENSG00000100393 EP300 o++b
ENSG00000109670 FBXW7 o+-
ENSG00000140564 FURIN o++a
ENSG00000116478 HDAC1 ---
ENSG00000100429 HDAC10 o--b
ENSG00000163517 HDAC11 -oo
ENSG00000196591 HDAC2 NonAssociatedWithProgression
ENSG00000171720 HDAC3 ---
ENSG00000068024 HDAC4 o--b
ENSG00000094631 HDAC6 o--a
ENSG00000061273 HDAC7 o--b
ENSG00000147099 HDAC8 oo-
ENSG00000114315 HES1 NonAssociatedWithProgression
ENSG00000197921 HES5 o--a
ENSG00000164683 HEY1 +o+
ENSG00000100644 HIF1A NonAssociatedWithProgression
ENSG00000078747 ITCH o++b
ENSG00000108773 KAT2A o--a
ENSG00000114166 KAT2B NonAssociatedWithProgression
ENSG00000161021 MAML1 o--b
ENSG00000013619 MAMLD1 oo+
ENSG00000100060 MFNG o--a
ENSG00000101752 MIB1 NonAssociatedWithProgression
ENSG00000197530 MIB2 ---
ENSG00000155363 MOV10 ---
ENSG00000136997 MYC o--b
ENSG00000141027 NCOR1 NonAssociatedWithProgression
ENSG00000196498 NCOR2 ---
ENSG00000162736 NCSTN o--b
ENSG00000148400 NOTCH1 o+o
ENSG00000134250 NOTCH2 o-o
ENSG00000074181 NOTCH3 o--b
ENSG00000101346 POFUT1 -oo
ENSG00000163389 POGLUT1 o++a
ENSG00000080815 PSEN1 o-o
ENSG00000205155 PSENEN NonAssociatedWithProgression
ENSG00000175582 RAB6A o++b
ENSG00000168214 RBPJ o--b
ENSG00000100387 RBX1 o--a
ENSG00000169733 RFNG o--a
ENSG00000143947 RPS27A o+o
ENSG00000113558 SKP1 ---
ENSG00000100603 SNW1 NonAssociatedWithProgression
ENSG00000126091 ST3GAL3 --o
ENSG00000110080 ST3GAL4 o-o
ENSG00000064225 ST3GAL6 o++a
ENSG00000101849 TBL1X +-o
ENSG00000177565 TBL1XR1 o-o
ENSG00000196781 TLE1 o--a
ENSG00000065717 TLE2 ---
ENSG00000140332 TLE3 ---
ENSG00000106829 TLE4 NonAssociatedWithProgression
ENSG00000086598 TMED2 +o+
ENSG00000090905 TNRC6A +-o
ENSG00000100354 TNRC6B o+o
ENSG00000141510 TP53 o--a
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---