PEACHi
GeneSet Signaling by ERBB4 (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-o- -2.1 0.04749 51.0 5.0 1.73
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000151694 ADAM17 +-o
ENSG00000142208 AKT1 ---
ENSG00000204673 AKT1S1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000117362 APH1A o--a
ENSG00000138613 APH1B o++b
ENSG00000166167 BTRC --o
ENSG00000170312 CDK1 o-+
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000118260 CREB1 o+-
ENSG00000055130 CUL1 o++a
ENSG00000118689 FOXO3 NonAssociatedWithProgression
ENSG00000184481 FOXO4 --o
ENSG00000177885 GRB2 NonAssociatedWithProgression
ENSG00000105723 GSK3A ---
ENSG00000082701 GSK3B -o-
ENSG00000113070 HBEGF o++a
ENSG00000174775 HRAS o--b
ENSG00000078747 ITCH o++b
ENSG00000096968 JAK2 o++a
ENSG00000133703 KRAS o+o
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000126934 MAP2K2 o--a
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000102882 MAPK3 o--b
ENSG00000119487 MAPKAP1 o--a
ENSG00000135679 MDM2 -o-
ENSG00000167965 MLST8 o--a
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000141027 NCOR1 NonAssociatedWithProgression
ENSG00000162736 NCSTN o--b
ENSG00000069869 NEDD4 -+o
ENSG00000213281 NRAS o--b
ENSG00000140992 PDPK1 -o-
ENSG00000081913 PHLPP1 NonAssociatedWithProgression
ENSG00000121879 PIK3CA +-o
ENSG00000145675 PIK3R1 o--a
ENSG00000172179 PRL o++a
ENSG00000080815 PSEN1 o-o
ENSG00000205155 PSENEN NonAssociatedWithProgression
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000179295 PTPN11 NonAssociatedWithProgression
ENSG00000132155 RAF1 NonAssociatedWithProgression
ENSG00000100387 RBX1 o--a
ENSG00000164327 RICTOR o--b
ENSG00000143947 RPS27A o+o
ENSG00000175634 RPS6KB2 -o-
ENSG00000178188 SH2B1 ---
ENSG00000160691 SHC1 o--a
ENSG00000113558 SKP1 ---
ENSG00000115904 SOS1 -+o
ENSG00000126561 STAT5A o-o
ENSG00000173757 STAT5B ---
ENSG00000055208 TAB2 o--b
ENSG00000101255 TRIB3 +-o
ENSG00000103197 TSC2 ---
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---
ENSG00000186153 WWOX NonAssociatedWithProgression
ENSG00000123124 WWP1 -o-
ENSG00000166913 YWHAB o--b