PEACHi
GeneSet Signaling by EGFR (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
+-o -2.5 0.03073 62.0 6.0 1.94
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000137845 ADAM10 NonAssociatedWithProgression
ENSG00000151694 ADAM17 +-o
ENSG00000138031 ADCY3 o-o
ENSG00000121281 ADCY7 -+o
ENSG00000173020 ADRBK1 o--b
ENSG00000142208 AKT1 ---
ENSG00000204673 AKT1S1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000196961 AP2A1 ---
ENSG00000006125 AP2B1 ---
ENSG00000161203 AP2M1 ---
ENSG00000042753 AP2S1 o--b
ENSG00000102606 ARHGEF7 NonAssociatedWithProgression
ENSG00000198668 CALM1 NonAssociatedWithProgression
ENSG00000152495 CAMK4 +-o
ENSG00000110395 CBL o--b
ENSG00000070831 CDC42 +oo
ENSG00000170312 CDK1 o-+
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000122705 CLTA +-o
ENSG00000141367 CLTC -o-
ENSG00000118260 CREB1 o+-
ENSG00000103653 CSK o--b
ENSG00000063245 EPN1 ---
ENSG00000085832 EPS15 +-o
ENSG00000127527 EPS15L1 ---
ENSG00000118689 FOXO3 NonAssociatedWithProgression
ENSG00000184481 FOXO4 --o
ENSG00000177885 GRB2 NonAssociatedWithProgression
ENSG00000105723 GSK3A ---
ENSG00000082701 GSK3B -o-
ENSG00000185359 HGS o--b
ENSG00000174775 HRAS o--b
ENSG00000150995 ITPR1 o++b
ENSG00000096433 ITPR3 o-o
ENSG00000133703 KRAS o+o
ENSG00000144749 LRIG1 -+o
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000126934 MAP2K2 o--a
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000102882 MAPK3 o--b
ENSG00000119487 MAPKAP1 o--a
ENSG00000135679 MDM2 -o-
ENSG00000167965 MLST8 o--a
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000213281 NRAS o--b
ENSG00000123360 PDE1B o-+
ENSG00000140992 PDPK1 -o-
ENSG00000081913 PHLPP1 NonAssociatedWithProgression
ENSG00000121879 PIK3CA +-o
ENSG00000145675 PIK3R1 o--a
ENSG00000072062 PRKACA ---
ENSG00000142875 PRKACB o--b
ENSG00000108946 PRKAR1A o+-
ENSG00000188191 PRKAR1B NonAssociatedWithProgression
ENSG00000154229 PRKCA oo+
ENSG00000163932 PRKCD NonAssociatedWithProgression
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000179295 PTPN11 NonAssociatedWithProgression
ENSG00000132155 RAF1 NonAssociatedWithProgression
ENSG00000164327 RICTOR o--b
ENSG00000143947 RPS27A o+o
ENSG00000175634 RPS6KB2 -o-
ENSG00000147010 SH3KBP1 +o+
ENSG00000160691 SHC1 o--a
ENSG00000115904 SOS1 -+o
ENSG00000164056 SPRY1 +o+
ENSG00000136158 SPRY2 o+o
ENSG00000136738 STAM NonAssociatedWithProgression
ENSG00000115145 STAM2 o+o
ENSG00000101255 TRIB3 +-o
ENSG00000103197 TSC2 ---
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---
ENSG00000166913 YWHAB o--b