GeneSet Platelet homeostasis (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++b -2.8 0.01963 29.0 7.0 2.32
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000174437 ATP2A2 -o-
ENSG00000074370 ATP2A3 o--b
ENSG00000070961 ATP2B1 +-o
ENSG00000157087 ATP2B2 o++b
ENSG00000058668 ATP2B4 o++b
ENSG00000000938 FGR o--b
ENSG00000087460 GNAS NonAssociatedWithProgression
ENSG00000078369 GNB1 o--a
ENSG00000172354 GNB2 ---
ENSG00000114450 GNB4 -+o
ENSG00000069966 GNB5 -o-
ENSG00000242616 GNG10 o++b
ENSG00000186469 GNG2 o++b
ENSG00000168243 GNG4 o--a
ENSG00000174021 GNG5 o+o
ENSG00000123201 GUCY1B2 NonAssociatedWithProgression
ENSG00000061918 GUCY1B3 -+o
ENSG00000150995 ITPR1 o++b
ENSG00000096433 ITPR3 o-o
ENSG00000135643 KCNMB4 NonAssociatedWithProgression
ENSG00000157193 LRP8 o--a
ENSG00000112062 MAPK14 o++b
ENSG00000182500 ORAI1 NonAssociatedWithProgression
ENSG00000108405 P2RX1 NonAssociatedWithProgression
ENSG00000112541 PDE10A o++b
ENSG00000123360 PDE1B o-+
ENSG00000138735 PDE5A o++a
ENSG00000113575 PPP2CA o--b
ENSG00000104695 PPP2CB +o+
ENSG00000105568 PPP2R1A o--b
ENSG00000137713 PPP2R1B o-+
ENSG00000066027 PPP2R5A o--b
ENSG00000068971 PPP2R5B NonAssociatedWithProgression
ENSG00000078304 PPP2R5C NonAssociatedWithProgression
ENSG00000112640 PPP2R5D o--a
ENSG00000154001 PPP2R5E o-o
ENSG00000179295 PTPN11 NonAssociatedWithProgression