PEACHi
GeneSet NUCLEOLUS (GO_-_Cellular_Component.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -7.0 3.0E-5 76.0 28.0 10.5
DownRegulated -4.6 6.6E-4 76.0 61.0 44.88
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000097007 ABL1 o--a
ENSG00000214274 ANG o++b
ENSG00000137074 APTX NonAssociatedWithProgression
ENSG00000198356 ASNA1 o--b
ENSG00000134152 C15orf29 NonAssociatedWithProgression
ENSG00000168564 CDKN2AIP NonAssociatedWithProgression
ENSG00000141076 CIRH1A NonAssociatedWithProgression
ENSG00000121058 COIL +-o
ENSG00000013573 DDX11 o--a
ENSG00000165732 DDX21 -o-
ENSG00000089737 DDX24 NonAssociatedWithProgression
ENSG00000213782 DDX47 o-o
ENSG00000136271 DDX56 o--b
ENSG00000158796 DEDD -o-
ENSG00000160570 DEDD2 o--a
ENSG00000130826 DKC1 o--b
ENSG00000128590 DNAJB9 o--b
ENSG00000134014 ELP3 o+o
ENSG00000171311 EXOSC1 NonAssociatedWithProgression
ENSG00000171824 EXOSC10 NonAssociatedWithProgression
ENSG00000123737 EXOSC9 o--b
ENSG00000105058 FAM32A o--b
ENSG00000102081 FMR1 o+-
ENSG00000114416 FXR1 ---
ENSG00000163938 GNL3 o--b
ENSG00000163565 IFI16 o--a
ENSG00000070061 IKBKAP NonAssociatedWithProgression
ENSG00000143621 ILF2 o-o
ENSG00000177971 IMP3 o--a
ENSG00000136718 IMP4 o--b
ENSG00000122550 KLHL7 o+o
ENSG00000111615 KRR1 o--b
ENSG00000145220 LYAR o--b
ENSG00000135679 MDM2 -o-
ENSG00000155438 MKI67IP NonAssociatedWithProgression
ENSG00000123562 MORF4L2 NonAssociatedWithProgression
ENSG00000124383 MPHOSPH10 o--b
ENSG00000132382 MYBBP1A o--b
ENSG00000115053 NCL o--b
ENSG00000186575 NF2 o--b
ENSG00000100138 NHP2L1 NonAssociatedWithProgression
ENSG00000184967 NOC4L o--a
ENSG00000140939 NOL3 --o
ENSG00000165271 NOL6 o--b
ENSG00000198000 NOL8 -oo
ENSG00000166197 NOLC1 o--b
ENSG00000146909 NOM1 o--b
ENSG00000181163 NPM1 o--b
ENSG00000037474 NSUN2 o--a
ENSG00000083635 NUFIP1 NonAssociatedWithProgression
ENSG00000143799 PARP1 o--b
ENSG00000140464 PML o-o
ENSG00000176903 PNMA1 +oo
ENSG00000115946 PNO1 -o-
ENSG00000101868 POLA1 NonAssociatedWithProgression
ENSG00000137054 POLR1E o--b
ENSG00000181222 POLR2A ---
ENSG00000104356 POP1 o+o
ENSG00000172336 POP7 o--a
ENSG00000011304 PTBP1 ---
ENSG00000168214 RBPJ o--b
ENSG00000148300 REXO4 o--b
ENSG00000142676 RPL11 o--b
ENSG00000100316 RPL3 -o-
ENSG00000136942 RPL35 o--b
ENSG00000130255 RPL36 o-o
ENSG00000148688 RPP30 NonAssociatedWithProgression
ENSG00000152464 RPP38 o+o
ENSG00000124787 RPP40 NonAssociatedWithProgression
ENSG00000105372 RPS19 -o-
ENSG00000171863 RPS7 o--a
ENSG00000160214 RRP1 ---
ENSG00000198301 SDAD1 o--a
ENSG00000174669 SLC29A2 ---
ENSG00000123415 SMUG1 NonAssociatedWithProgression
ENSG00000115306 SPTBN1 oo-
ENSG00000167881 SRP68 o-+
ENSG00000148296 SURF6 NonAssociatedWithProgression
ENSG00000148835 TAF5 o--a
ENSG00000070814 TCOF1 o--b
ENSG00000173451 THAP2 -+o
ENSG00000198900 TOP1 o+o
ENSG00000131747 TOP2A o--b
ENSG00000077097 TOP2B o+o
ENSG00000141510 TP53 o--a
ENSG00000184205 TSPYL2 o--b
ENSG00000108312 UBTF o--a
ENSG00000011260 UTP18 NonAssociatedWithProgression
ENSG00000120800 UTP20 NonAssociatedWithProgression
ENSG00000132467 UTP3 o++b
ENSG00000165392 WRN +oo
ENSG00000088930 XRN2 NonAssociatedWithProgression
ENSG00000109917 ZNF259 o--b
ENSG00000171606 ZNF274 o--a
ENSG00000109445 ZNF330 o++b
ENSG00000113761 ZNF346 -o-
ENSG00000081665 ZNF506 NonAssociatedWithProgression