GeneSet NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -3.0 0.04404 17.0 7.0 2.35
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000166313 APBB1 o-o
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000116584 ARHGEF2 o--b
ENSG00000069399 BCL3 NonAssociatedWithProgression
ENSG00000070831 CDC42 +oo
ENSG00000074054 CLASP1 NonAssociatedWithProgression
ENSG00000136770 DNAJC1 NonAssociatedWithProgression
ENSG00000086232 EIF2AK1 NonAssociatedWithProgression
ENSG00000172071 EIF2AK3 NonAssociatedWithProgression
ENSG00000141543 EIF4A3 NonAssociatedWithProgression
ENSG00000140564 FURIN o++a
ENSG00000107937 GTPBP4 o--b
ENSG00000140854 KATNB1 o--b
ENSG00000050405 LIMA1 -+o
ENSG00000101367 MAPRE1 o--b
ENSG00000198625 MDM4 o-o
ENSG00000186010 NDUFA13 o-o
ENSG00000186575 NF2 o--b
ENSG00000120727 PAIP2 NonAssociatedWithProgression
ENSG00000119383 PPP2R4 ---
ENSG00000119335 SET o--b
ENSG00000185187 SIGIRR o--b
ENSG00000185338 SOCS1 o--a
ENSG00000102265 TIMP1 o--a
ENSG00000154620 TMSB4Y o+o
ENSG00000163519 TRAT1 NonAssociatedWithProgression
ENSG00000165699 TSC1 NonAssociatedWithProgression