PEACHi
GeneSet Mitochondrial Protein Import (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-oo -2.9 0.0193 41.0 4.0 0.84
AllGenesAssociatedWithProgression -2.7 0.02284 46.0 41.0 33.51
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000100412 ACO2 -oo
ENSG00000152234 ATP5A1 -o-
ENSG00000110955 ATP5B o--b
ENSG00000159199 ATP5G1 NonAssociatedWithProgression
ENSG00000074582 BCS1L o-o
ENSG00000173085 COQ2 o--b
ENSG00000138495 COX17 o+-
ENSG00000062485 CS +-o
ENSG00000179091 CYC1 ---
ENSG00000205981 DNAJC19 o--b
ENSG00000132286 FXC1 o--a
ENSG00000165060 FXN -oo
ENSG00000127554 GFER ---
ENSG00000109519 GRPEL1 o--b
ENSG00000164284 GRPEL2 o-o
ENSG00000100209 HSCB o+-
ENSG00000113013 HSPA9 o--b
ENSG00000144381 HSPD1 o--b
ENSG00000067829 IDH3G ---
ENSG00000173171 MTX1 o--a
ENSG00000128654 MTX2 o++b
ENSG00000165688 PMPCA o--a
ENSG00000105819 PMPCB o+o
ENSG00000100347 SAMM50 NonAssociatedWithProgression
ENSG00000115840 SLC25A12 o++a
ENSG00000004864 SLC25A13 NonAssociatedWithProgression
ENSG00000151729 SLC25A4 -oo
ENSG00000169100 SLC25A6 o-o
ENSG00000102125 TAZ o-+
ENSG00000134809 TIMM10 o-o
ENSG00000099800 TIMM13 o--a
ENSG00000134375 TIMM17A -oo
ENSG00000126768 TIMM17B --o
ENSG00000138297 TIMM23 o--a
ENSG00000104980 TIMM44 ---
ENSG00000105197 TIMM50 ---
ENSG00000126953 TIMM8A NonAssociatedWithProgression
ENSG00000150779 TIMM8B --o
ENSG00000100575 TIMM9 -+o
ENSG00000173726 TOMM20 +-o
ENSG00000100216 TOMM22 o--b
ENSG00000130204 TOMM40 o--a
ENSG00000214736 TOMM6 o--b
ENSG00000196683 TOMM7 NonAssociatedWithProgression
ENSG00000154174 TOMM70A o+-
ENSG00000213585 VDAC1 --o