PEACHi
GeneSet Metabolism of vitamins and cofactors (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-+o -2.5 0.03156 32.0 5.0 1.49
AllGenesAssociatedWithProgression -2.8 0.0182 35.0 32.0 25.5
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000149313 AASDHPPT o+o
ENSG00000068120 COASY o-o
ENSG00000166347 CYB5A o++b
ENSG00000100243 CYB5R3 o-o
ENSG00000228716 DHFR o++a
ENSG00000169710 FASN o--b
ENSG00000160688 FLAD1 o--b
ENSG00000136877 FPGS o--a
ENSG00000171723 GPHN -+o
ENSG00000148834 GSTO1 o-o
ENSG00000124615 MOCS1 o--a
ENSG00000164172 MOCS2 -+o
ENSG00000100714 MTHFD1 -+o
ENSG00000177000 MTHFR o-o
ENSG00000008130 NADK o--a
ENSG00000172890 NADSYN1 o--a
ENSG00000105835 NAMPT NonAssociatedWithProgression
ENSG00000244005 NFS1 NonAssociatedWithProgression
ENSG00000152782 PANK1 o++b
ENSG00000125779 PANK2 +-o
ENSG00000120137 PANK3 +oo
ENSG00000157881 PANK4 o--b
ENSG00000160209 PDXK -+o
ENSG00000108439 PNPO o--a
ENSG00000127125 PPCS o++a
ENSG00000103485 QPRT o--a
ENSG00000176974 SHMT1 o--a
ENSG00000173638 SLC19A1 ---
ENSG00000117479 SLC19A2 +o+
ENSG00000089057 SLC23A2 +-o
ENSG00000164933 SLC25A32 +-o
ENSG00000117394 SLC2A1 o--b
ENSG00000059804 SLC2A3 NonAssociatedWithProgression
ENSG00000138074 SLC5A6 ---
ENSG00000196511 TPK1 -+o