PEACHi
GeneSet KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++a -2.6 0.0404 42.0 6.0 1.92
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000064012 CASP8 +-o
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000143387 CTSK oo+
ENSG00000168040 FADD o--b
ENSG00000170345 FOS NonAssociatedWithProgression
ENSG00000142166 IFNAR1 NonAssociatedWithProgression
ENSG00000159110 IFNAR2 -oo
ENSG00000104365 IKBKB o++a
ENSG00000143466 IKBKE ---
ENSG00000073009 IKBKG --o
ENSG00000184216 IRAK1 o--a
ENSG00000198001 IRAK4 o--a
ENSG00000126456 IRF3 o--a
ENSG00000185507 IRF7 ---
ENSG00000177606 JUN NonAssociatedWithProgression
ENSG00000154589 LY96 o++a
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000126934 MAP2K2 o--a
ENSG00000034152 MAP2K3 ---
ENSG00000065559 MAP2K4 NonAssociatedWithProgression
ENSG00000076984 MAP2K7 ---
ENSG00000135341 MAP3K7 NonAssociatedWithProgression
ENSG00000107968 MAP3K8 o++a
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000112062 MAPK14 o++b
ENSG00000102882 MAPK3 o--b
ENSG00000107643 MAPK8 o+o
ENSG00000050748 MAPK9 -o-
ENSG00000172936 MYD88 +o+
ENSG00000109320 NFKB1 o++a
ENSG00000100906 NFKBIA o-o
ENSG00000121879 PIK3CA +-o
ENSG00000051382 PIK3CB -o-
ENSG00000171608 PIK3CD o++a
ENSG00000105851 PIK3CG o++b
ENSG00000145675 PIK3R1 o--a
ENSG00000105647 PIK3R2 o--a
ENSG00000117461 PIK3R3 NonAssociatedWithProgression
ENSG00000136238 RAC1 NonAssociatedWithProgression
ENSG00000173039 RELA o--a
ENSG00000137275 RIPK1 o--b
ENSG00000115415 STAT1 oo+
ENSG00000055208 TAB2 o--b
ENSG00000183735 TBK1 o++b
ENSG00000127666 TICAM1 o--b
ENSG00000150455 TIRAP -+o
ENSG00000187554 TLR5 o++a
ENSG00000078902 TOLLIP o-o
ENSG00000131323 TRAF3 -+o
ENSG00000175104 TRAF6 NonAssociatedWithProgression