PEACHi
GeneSet KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++a -2.7 0.035 30.0 5.0 1.37
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000151726 ACSL1 NonAssociatedWithProgression
ENSG00000123983 ACSL3 NonAssociatedWithProgression
ENSG00000068366 ACSL4 o+-
ENSG00000159346 ADIPOR1 NonAssociatedWithProgression
ENSG00000006831 ADIPOR2 oo-
ENSG00000142208 AKT1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000004660 CAMKK1 ---
ENSG00000110931 CAMKK2 NonAssociatedWithProgression
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000110090 CPT1A --o
ENSG00000205560 CPT1B o--a
ENSG00000104365 IKBKB o++a
ENSG00000073009 IKBKG --o
ENSG00000169047 IRS1 o--b
ENSG00000185950 IRS2 NonAssociatedWithProgression
ENSG00000096968 JAK2 o++a
ENSG00000116678 LEPR NonAssociatedWithProgression
ENSG00000107643 MAPK8 o+o
ENSG00000050748 MAPK9 -o-
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000109320 NFKB1 o++a
ENSG00000100906 NFKBIA o-o
ENSG00000104825 NFKBIB ---
ENSG00000146232 NFKBIE o--b
ENSG00000186951 PPARA o++a
ENSG00000132356 PRKAA1 -o-
ENSG00000162409 PRKAA2 o++a
ENSG00000111725 PRKAB1 ---
ENSG00000131791 PRKAB2 NonAssociatedWithProgression
ENSG00000181929 PRKAG1 ---
ENSG00000065675 PRKCQ o+o
ENSG00000179295 PTPN11 NonAssociatedWithProgression
ENSG00000173039 RELA o--a
ENSG00000186350 RXRA ---
ENSG00000204231 RXRB NonAssociatedWithProgression
ENSG00000117394 SLC2A1 o--b
ENSG00000168610 STAT3 o--b
ENSG00000118046 STK11 o--a
ENSG00000067182 TNFRSF1A NonAssociatedWithProgression
ENSG00000102871 TRADD NonAssociatedWithProgression
ENSG00000127191 TRAF2 o--b