GeneSet Interferon gamma signaling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
UpRegulated -2.7 0.03061 20.0 11.0 5.41
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000166710 B2M o+o
ENSG00000145349 CAMK2D NonAssociatedWithProgression
ENSG00000148660 CAMK2G o+o
ENSG00000026508 CD44 o++b
ENSG00000206503 HLA-A +-o
ENSG00000234745 HLA-B o-+
ENSG00000204525 HLA-C o-+
ENSG00000204592 HLA-E +-o
ENSG00000216490 IFI30 oo+
ENSG00000027697 IFNGR1 NonAssociatedWithProgression
ENSG00000159128 IFNGR2 o++a
ENSG00000125347 IRF1 o+o
ENSG00000168310 IRF2 o++b
ENSG00000126456 IRF3 o--a
ENSG00000185507 IRF7 ---
ENSG00000213928 IRF9 NonAssociatedWithProgression
ENSG00000162434 JAK1 o--b
ENSG00000096968 JAK2 o++a
ENSG00000125148 MT2A NonAssociatedWithProgression
ENSG00000140464 PML o-o
ENSG00000163932 PRKCD NonAssociatedWithProgression
ENSG00000196396 PTPN1 +oo
ENSG00000179295 PTPN11 NonAssociatedWithProgression
ENSG00000175354 PTPN2 NonAssociatedWithProgression
ENSG00000185338 SOCS1 o--a
ENSG00000067066 SP100 o++b
ENSG00000115415 STAT1 oo+
ENSG00000116030 SUMO1 NonAssociatedWithProgression