PEACHi
GeneSet Influenza Life Cycle (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-o- -2.5 0.02903 88.0 8.0 2.98
o--a -2.3 0.03787 88.0 21.0 12.5
o-o -4.5 0.00318 88.0 19.0 7.38
DownRegulated -6.5 1.0E-5 88.0 73.0 51.97
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000094914 AAAS o--a
ENSG00000179218 CALR ---
ENSG00000127022 CANX NonAssociatedWithProgression
ENSG00000122705 CLTA +-o
ENSG00000141367 CLTC -o-
ENSG00000102580 DNAJC3 NonAssociatedWithProgression
ENSG00000149806 FAU o-o
ENSG00000132463 GRSF1 o--a
ENSG00000125651 GTF2F1 o--a
ENSG00000188342 GTF2F2 NonAssociatedWithProgression
ENSG00000080824 HSP90AA1 NonAssociatedWithProgression
ENSG00000204389 HSPA1A o--b
ENSG00000065150 IPO5 -o-
ENSG00000114030 KPNA1 NonAssociatedWithProgression
ENSG00000108424 KPNB1 o--a
ENSG00000111581 NUP107 -+o
ENSG00000069248 NUP133 o+-
ENSG00000124789 NUP153 o+-
ENSG00000113569 NUP155 NonAssociatedWithProgression
ENSG00000030066 NUP160 NonAssociatedWithProgression
ENSG00000095319 NUP188 ---
ENSG00000155561 NUP205 -o-
ENSG00000132182 NUP210 o-o
ENSG00000126883 NUP214 NonAssociatedWithProgression
ENSG00000163002 NUP35 oo-
ENSG00000075188 NUP37 NonAssociatedWithProgression
ENSG00000093000 NUP50 NonAssociatedWithProgression
ENSG00000138750 NUP54 o-o
ENSG00000213024 NUP62 o--a
ENSG00000125450 NUP85 o--b
ENSG00000108559 NUP88 NonAssociatedWithProgression
ENSG00000102900 NUP93 o-o
ENSG00000110713 NUP98 o--a
ENSG00000139496 NUPL1 +-o
ENSG00000136243 NUPL2 o+-
ENSG00000181222 POLR2A ---
ENSG00000047315 POLR2B +oo
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000144231 POLR2D o--b
ENSG00000100142 POLR2F NonAssociatedWithProgression
ENSG00000168002 POLR2G NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000105258 POLR2I --o
ENSG00000005075 POLR2J ---
ENSG00000177700 POLR2L o-o
ENSG00000196313 POM121 o--b
ENSG00000101146 RAE1 -o-
ENSG00000132341 RAN o--b
ENSG00000153201 RANBP2 o+o
ENSG00000147403 RPL10 o-o
ENSG00000198755 RPL10A NonAssociatedWithProgression
ENSG00000142676 RPL11 o--b
ENSG00000197958 RPL12 NonAssociatedWithProgression
ENSG00000167526 RPL13 o--b
ENSG00000142541 RPL13A NonAssociatedWithProgression
ENSG00000188846 RPL14 o--a
ENSG00000174748 RPL15 o--a
ENSG00000215472 RPL17 o-o
ENSG00000105640 RPL18A o-o
ENSG00000108298 RPL19 o-o
ENSG00000122026 RPL21 o--a
ENSG00000116251 RPL22 +-o
ENSG00000125691 RPL23 NonAssociatedWithProgression
ENSG00000198242 RPL23A o--a
ENSG00000114391 RPL24 o--b
ENSG00000161970 RPL26 o-o
ENSG00000131469 RPL27 NonAssociatedWithProgression
ENSG00000166441 RPL27A o--a
ENSG00000108107 RPL28 o--b
ENSG00000162244 RPL29 o--a
ENSG00000100316 RPL3 -o-
ENSG00000156482 RPL30 o++b
ENSG00000071082 RPL31 o-+
ENSG00000144713 RPL32 NonAssociatedWithProgression
ENSG00000109475 RPL34 NonAssociatedWithProgression
ENSG00000136942 RPL35 o--b
ENSG00000182899 RPL35A NonAssociatedWithProgression
ENSG00000130255 RPL36 o-o
ENSG00000241343 RPL36A ---
ENSG00000145592 RPL37 NonAssociatedWithProgression
ENSG00000197756 RPL37A NonAssociatedWithProgression
ENSG00000198918 RPL39 o-+
ENSG00000174444 RPL4 o--b
ENSG00000122406 RPL5 NonAssociatedWithProgression
ENSG00000089009 RPL6 o--b
ENSG00000147604 RPL7 NonAssociatedWithProgression
ENSG00000148303 RPL7A -o-
ENSG00000161016 RPL8 ---
ENSG00000163682 RPL9 NonAssociatedWithProgression
ENSG00000089157 RPLP0 o--b
ENSG00000137818 RPLP1 NonAssociatedWithProgression
ENSG00000177600 RPLP2 NonAssociatedWithProgression
ENSG00000124614 RPS10 NonAssociatedWithProgression
ENSG00000142534 RPS11 o--a
ENSG00000112306 RPS12 o--a
ENSG00000110700 RPS13 NonAssociatedWithProgression
ENSG00000164587 RPS14 -o-
ENSG00000115268 RPS15 NonAssociatedWithProgression
ENSG00000134419 RPS15A o+-
ENSG00000105193 RPS16 o--b
ENSG00000231500 RPS18 o-o
ENSG00000105372 RPS19 -o-
ENSG00000140988 RPS2 o--a
ENSG00000008988 RPS20 o--a
ENSG00000186468 RPS23 o-o
ENSG00000138326 RPS24 NonAssociatedWithProgression
ENSG00000197728 RPS26 NonAssociatedWithProgression
ENSG00000177954 RPS27 o-o
ENSG00000143947 RPS27A o+o
ENSG00000233927 RPS28 o-o
ENSG00000213741 RPS29 NonAssociatedWithProgression
ENSG00000149273 RPS3 o--b
ENSG00000145425 RPS3A o-o
ENSG00000198034 RPS4X NonAssociatedWithProgression
ENSG00000129824 RPS4Y1 o--a
ENSG00000083845 RPS5 o--a
ENSG00000137154 RPS6 o--a
ENSG00000171863 RPS7 o--a
ENSG00000142937 RPS8 NonAssociatedWithProgression
ENSG00000170889 RPS9 o--b
ENSG00000168028 RPSA o--b
ENSG00000085415 SEH1L o-o
ENSG00000047410 TPR o+-
ENSG00000221983 UBA52 o--a
ENSG00000082898 XPO1 o-o