GeneSet Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o-+ -2.8 0.01955 18.0 3.0 0.52
MixedRegulation -2.8 0.02642 18.0 7.0 2.5
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000160593 AMICA1 NonAssociatedWithProgression
ENSG00000166710 B2M o+o
ENSG00000198821 CD247 NonAssociatedWithProgression
ENSG00000167286 CD3D NonAssociatedWithProgression
ENSG00000198851 CD3E o--a
ENSG00000160654 CD3G ---
ENSG00000110651 CD81 o--b
ENSG00000153563 CD8A NonAssociatedWithProgression
ENSG00000153283 CD96 o++a
ENSG00000154639 CXADR NonAssociatedWithProgression
ENSG00000126264 HCST o-+
ENSG00000206503 HLA-A +-o
ENSG00000234745 HLA-B o-+
ENSG00000204525 HLA-C o-+
ENSG00000204592 HLA-E +-o
ENSG00000108622 ICAM2 NonAssociatedWithProgression
ENSG00000185885 IFITM1 o--a
ENSG00000115232 ITGA4 o--b
ENSG00000005844 ITGAL NonAssociatedWithProgression
ENSG00000150093 ITGB1 NonAssociatedWithProgression
ENSG00000160255 ITGB2 o--a
ENSG00000139187 KLRG1 -+o
ENSG00000204516 MICB o-o
ENSG00000188404 SELL -+o
ENSG00000211889 TRAC o--b
ENSG00000111981 ULBP1 +oo