PEACHi
GeneSet HIV Late Phase of HIV Life Cycle (HIV_Collection.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o-o -2.5 0.03924 67.0 12.0 5.62
DownRegulated -2.3 0.03781 67.0 49.0 39.57
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000094914 AAAS o--a
ENSG00000134480 CCNH -o-
ENSG00000082258 CCNT2 o-o
ENSG00000134058 CDK7 o+o
ENSG00000188986 COBRA1 o--b
ENSG00000060069 CTDP1 ---
ENSG00000105656 ELL o--a
ENSG00000104884 ERCC2 ---
ENSG00000163161 ERCC3 o-o
ENSG00000140307 GTF2A2 NonAssociatedWithProgression
ENSG00000137947 GTF2B NonAssociatedWithProgression
ENSG00000153767 GTF2E1 o++b
ENSG00000197265 GTF2E2 NonAssociatedWithProgression
ENSG00000125651 GTF2F1 o--a
ENSG00000188342 GTF2F2 NonAssociatedWithProgression
ENSG00000110768 GTF2H1 o++b
ENSG00000145736 GTF2H2 o++b
ENSG00000111358 GTF2H3 NonAssociatedWithProgression
ENSG00000136937 NCBP1 o+-
ENSG00000114503 NCBP2 o--b
ENSG00000136448 NMT1 o--b
ENSG00000152465 NMT2 NonAssociatedWithProgression
ENSG00000111581 NUP107 -+o
ENSG00000069248 NUP133 o+-
ENSG00000124789 NUP153 o+-
ENSG00000113569 NUP155 NonAssociatedWithProgression
ENSG00000030066 NUP160 NonAssociatedWithProgression
ENSG00000095319 NUP188 ---
ENSG00000155561 NUP205 -o-
ENSG00000132182 NUP210 o-o
ENSG00000126883 NUP214 NonAssociatedWithProgression
ENSG00000163002 NUP35 oo-
ENSG00000075188 NUP37 NonAssociatedWithProgression
ENSG00000093000 NUP50 NonAssociatedWithProgression
ENSG00000138750 NUP54 o-o
ENSG00000213024 NUP62 o--a
ENSG00000125450 NUP85 o--b
ENSG00000108559 NUP88 NonAssociatedWithProgression
ENSG00000102900 NUP93 o-o
ENSG00000110713 NUP98 o--a
ENSG00000139496 NUPL1 +-o
ENSG00000136243 NUPL2 o+-
ENSG00000181222 POLR2A ---
ENSG00000047315 POLR2B +oo
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000144231 POLR2D o--b
ENSG00000100142 POLR2F NonAssociatedWithProgression
ENSG00000168002 POLR2G NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000105258 POLR2I --o
ENSG00000005075 POLR2J ---
ENSG00000177700 POLR2L o-o
ENSG00000196313 POM121 o--b
ENSG00000101146 RAE1 -o-
ENSG00000132341 RAN o--b
ENSG00000099901 RANBP1 NonAssociatedWithProgression
ENSG00000153201 RANBP2 o+o
ENSG00000100401 RANGAP1 o-o
ENSG00000180198 RCC1 o--a
ENSG00000204356 RDBP o-o
ENSG00000111880 RNGTT NonAssociatedWithProgression
ENSG00000101654 RNMT NonAssociatedWithProgression
ENSG00000143947 RPS27A o+o
ENSG00000085415 SEH1L o-o
ENSG00000149136 SSRP1 o--b
ENSG00000092201 SUPT16H o--a
ENSG00000213246 SUPT4H1 o--a
ENSG00000196235 SUPT5H o--b
ENSG00000147133 TAF1 NonAssociatedWithProgression
ENSG00000166337 TAF10 o--a
ENSG00000064995 TAF11 o--b
ENSG00000120656 TAF12 o--a
ENSG00000197780 TAF13 o+o
ENSG00000130699 TAF4 o++b
ENSG00000141384 TAF4B NonAssociatedWithProgression
ENSG00000148835 TAF5 o--a
ENSG00000106290 TAF6 NonAssociatedWithProgression
ENSG00000085231 TAF9 o+o
ENSG00000112592 TBP NonAssociatedWithProgression
ENSG00000187735 TCEA1 NonAssociatedWithProgression
ENSG00000154582 TCEB1 NonAssociatedWithProgression
ENSG00000103363 TCEB2 o--a
ENSG00000011007 TCEB3 NonAssociatedWithProgression
ENSG00000101158 TH1L o--b
ENSG00000047410 TPR o+-
ENSG00000074319 TSG101 NonAssociatedWithProgression
ENSG00000221983 UBA52 o--a
ENSG00000170315 UBB ---
ENSG00000160948 VPS28 o-o
ENSG00000155975 VPS37A +o+
ENSG00000139722 VPS37B o--b
ENSG00000185049 WHSC2 o--b
ENSG00000082898 XPO1 o-o