PEACHi
GeneSet BIOCARTA_TCR_PATHWAY (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -2.6 0.0404 27.0 9.0 3.83
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000198668 CALM1 NonAssociatedWithProgression
ENSG00000143933 CALM2 o--a
ENSG00000160014 CALM3 o--a
ENSG00000198821 CD247 NonAssociatedWithProgression
ENSG00000167286 CD3D NonAssociatedWithProgression
ENSG00000198851 CD3E o--a
ENSG00000160654 CD3G ---
ENSG00000126767 ELK1 ---
ENSG00000170345 FOS NonAssociatedWithProgression
ENSG00000010810 FYN +oo
ENSG00000177885 GRB2 NonAssociatedWithProgression
ENSG00000174775 HRAS o--b
ENSG00000177606 JUN NonAssociatedWithProgression
ENSG00000213658 LAT NonAssociatedWithProgression
ENSG00000182866 LCK o-o
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000065559 MAP2K4 NonAssociatedWithProgression
ENSG00000095015 MAP3K1 o--a
ENSG00000102882 MAPK3 o--b
ENSG00000107643 MAPK8 o+o
ENSG00000131196 NFATC1 o--b
ENSG00000072736 NFATC3 o--a
ENSG00000109320 NFKB1 o++a
ENSG00000100906 NFKBIA o-o
ENSG00000121879 PIK3CA +-o
ENSG00000105851 PIK3CG o++b
ENSG00000145675 PIK3R1 o--a
ENSG00000138814 PPP3CA o++b
ENSG00000107758 PPP3CB o+-
ENSG00000120910 PPP3CC NonAssociatedWithProgression
ENSG00000154229 PRKCA oo+
ENSG00000143851 PTPN7 o--b
ENSG00000136238 RAC1 NonAssociatedWithProgression
ENSG00000132155 RAF1 NonAssociatedWithProgression
ENSG00000145715 RASA1 NonAssociatedWithProgression
ENSG00000173039 RELA o--a
ENSG00000160691 SHC1 o--a
ENSG00000115904 SOS1 -+o
ENSG00000141968 VAV1 o--a
ENSG00000115085 ZAP70 o--b