GeneSet mRNA Splicing - Minor Pathway (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -2.6 0.03517 28.0 23.0 16.54
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000174243 DDX23 -o-
ENSG00000108883 EFTUD2 -o-
ENSG00000125651 GTF2F1 o--a
ENSG00000188342 GTF2F2 NonAssociatedWithProgression
ENSG00000204392 LSM2 --o
ENSG00000136937 NCBP1 o+-
ENSG00000114503 NCBP2 o--b
ENSG00000100138 NHP2L1 NonAssociatedWithProgression
ENSG00000181222 POLR2A ---
ENSG00000047315 POLR2B +oo
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000144231 POLR2D o--b
ENSG00000100142 POLR2F NonAssociatedWithProgression
ENSG00000168002 POLR2G NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000105258 POLR2I --o
ENSG00000005075 POLR2J ---
ENSG00000177700 POLR2L o-o
ENSG00000101161 PRPF6 o-o
ENSG00000174231 PRPF8 o--b
ENSG00000115524 SF3B1 o++b
ENSG00000087365 SF3B2 NonAssociatedWithProgression
ENSG00000189091 SF3B3 NonAssociatedWithProgression
ENSG00000143368 SF3B4 o--b
ENSG00000169976 SF3B5 o--a
ENSG00000144028 SNRNP200 NonAssociatedWithProgression
ENSG00000060688 SNRNP40 ---
ENSG00000125835 SNRPB o--a
ENSG00000167088 SNRPD1 o--a
ENSG00000125743 SNRPD2 o--a
ENSG00000100028 SNRPD3 o-o
ENSG00000182004 SNRPE NonAssociatedWithProgression
ENSG00000143977 SNRPG o+-
ENSG00000136450 SRSF1 -o-
ENSG00000161547 SRSF2 oo-
ENSG00000124193 SRSF6 +-o
ENSG00000115875 SRSF7 o--b
ENSG00000141759 TXNL4A NonAssociatedWithProgression