GeneSet Transport of Mature Transcript to Cytoplasm (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-o- -2.7 0.02198 39.0 5.0 1.32
o+- -2.8 0.01955 39.0 5.0 1.26
+-o -2.2 0.04638 39.0 4.0 1.22
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000094914 AAAS o--a
ENSG00000168438 CDC40 -oo
ENSG00000071894 CPSF1 o--a
ENSG00000165934 CPSF2 NonAssociatedWithProgression
ENSG00000140829 DHX38 o--a
ENSG00000162385 MAGOH o--b
ENSG00000136937 NCBP1 o+-
ENSG00000114503 NCBP2 o--b
ENSG00000086102 NFX1 NonAssociatedWithProgression
ENSG00000111581 NUP107 -+o
ENSG00000069248 NUP133 o+-
ENSG00000124789 NUP153 o+-
ENSG00000113569 NUP155 NonAssociatedWithProgression
ENSG00000030066 NUP160 NonAssociatedWithProgression
ENSG00000095319 NUP188 ---
ENSG00000155561 NUP205 -o-
ENSG00000132182 NUP210 o-o
ENSG00000126883 NUP214 NonAssociatedWithProgression
ENSG00000163002 NUP35 oo-
ENSG00000075188 NUP37 NonAssociatedWithProgression
ENSG00000093000 NUP50 NonAssociatedWithProgression
ENSG00000138750 NUP54 o-o
ENSG00000213024 NUP62 o--a
ENSG00000125450 NUP85 o--b
ENSG00000108559 NUP88 NonAssociatedWithProgression
ENSG00000102900 NUP93 o-o
ENSG00000110713 NUP98 o--a
ENSG00000139496 NUPL1 +-o
ENSG00000136243 NUPL2 o+-
ENSG00000162231 NXF1 o--a
ENSG00000196313 POM121 o--b
ENSG00000101146 RAE1 -o-
ENSG00000153201 RANBP2 o+o
ENSG00000131795 RBM8A +-o
ENSG00000205937 RNPS1 NonAssociatedWithProgression
ENSG00000085415 SEH1L o-o
ENSG00000163950 SLBP NonAssociatedWithProgression
ENSG00000133226 SRRM1 o--b
ENSG00000136450 SRSF1 -o-
ENSG00000116754 SRSF11 NonAssociatedWithProgression
ENSG00000161547 SRSF2 oo-
ENSG00000112081 SRSF3 +-o
ENSG00000116350 SRSF4 o--a
ENSG00000100650 SRSF5 o--b
ENSG00000124193 SRSF6 +-o
ENSG00000115875 SRSF7 o--b
ENSG00000111786 SRSF9 -o-
ENSG00000183684 THOC4 -o-
ENSG00000047410 TPR o+-
ENSG00000160201 U2AF1 NonAssociatedWithProgression
ENSG00000063244 U2AF2 ---
ENSG00000125351 UPF3B NonAssociatedWithProgression