PEACHi
GeneSet PKB-mediated events (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -2.7 0.02203 18.0 7.0 2.56
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000105221 AKT2 o--a
ENSG00000135932 CAB39 +o+
ENSG00000102547 CAB39L -+o
ENSG00000103319 EEF2K o++a
ENSG00000063046 EIF4B o--a
ENSG00000187840 EIF4EBP1 o--b
ENSG00000114867 EIF4G1 ---
ENSG00000167965 MLST8 o--a
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000100614 PPM1A o--a
ENSG00000132356 PRKAA1 -o-
ENSG00000162409 PRKAA2 o++a
ENSG00000111725 PRKAB1 ---
ENSG00000131791 PRKAB2 NonAssociatedWithProgression
ENSG00000181929 PRKAG1 ---
ENSG00000106615 RHEB NonAssociatedWithProgression
ENSG00000137154 RPS6 o--a
ENSG00000108443 RPS6KB1 NonAssociatedWithProgression
ENSG00000141564 RPTOR o--a
ENSG00000118046 STK11 o--a
ENSG00000125695 STRADA ---
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000103197 TSC2 ---