GeneSet PI3K events in ERBB2 signaling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
-o- -3.2 0.01135 21.0 4.0 0.71
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000204673 AKT1S1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000118260 CREB1 o+-
ENSG00000118689 FOXO3 NonAssociatedWithProgression
ENSG00000184481 FOXO4 --o
ENSG00000177885 GRB2 NonAssociatedWithProgression
ENSG00000105723 GSK3A ---
ENSG00000082701 GSK3B -o-
ENSG00000113070 HBEGF o++a
ENSG00000119487 MAPKAP1 o--a
ENSG00000135679 MDM2 -o-
ENSG00000167965 MLST8 o--a
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000140992 PDPK1 -o-
ENSG00000081913 PHLPP1 NonAssociatedWithProgression
ENSG00000121879 PIK3CA +-o
ENSG00000145675 PIK3R1 o--a
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000164327 RICTOR o--b
ENSG00000175634 RPS6KB2 -o-
ENSG00000101255 TRIB3 +-o
ENSG00000103197 TSC2 ---