PEACHi
GeneSet NEGATIVE_REGULATION_OF_CELL_CYCLE (GO_-_Biological_Process.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -3.7 0.02707 40.0 14.0 5.68
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000204472 AIF1 o--a
ENSG00000166313 APBB1 o-o
ENSG00000134982 APC NonAssociatedWithProgression
ENSG00000125378 BMP4 +-o
ENSG00000154640 BTG3 NonAssociatedWithProgression
ENSG00000151465 CDC123 NonAssociatedWithProgression
ENSG00000101391 CDK5RAP1 o--a
ENSG00000111276 CDKN1B +o+
ENSG00000123080 CDKN2C o-o
ENSG00000100526 CDKN3 NonAssociatedWithProgression
ENSG00000131165 CHMP1A o--a
ENSG00000055130 CUL1 o++a
ENSG00000108094 CUL2 o+o
ENSG00000036257 CUL3 o--a
ENSG00000139842 CUL4A oo-
ENSG00000166266 CUL5 o--b
ENSG00000100867 DHRS2 NonAssociatedWithProgression
ENSG00000075711 DLG1 NonAssociatedWithProgression
ENSG00000110321 EIF4G2 o+-
ENSG00000184481 FOXO4 --o
ENSG00000116717 GADD45A o+o
ENSG00000180447 GAS1 o++b
ENSG00000007237 GAS7 ---
ENSG00000112312 GMNN NonAssociatedWithProgression
ENSG00000186834 HEXIM1 o--a
ENSG00000168517 HEXIM2 NonAssociatedWithProgression
ENSG00000111653 ING4 o+-
ENSG00000152409 JMY o--a
ENSG00000121774 KHDRBS1 NonAssociatedWithProgression
ENSG00000150457 LATS2 o++a
ENSG00000116688 MFN2 o--b
ENSG00000136997 MYC o--b
ENSG00000104320 NBN NonAssociatedWithProgression
ENSG00000134250 NOTCH2 o-o
ENSG00000170515 PA2G4 NonAssociatedWithProgression
ENSG00000090097 PCBP4 o-o
ENSG00000118495 PLAGL1 NonAssociatedWithProgression
ENSG00000115241 PPM1G o--a
ENSG00000087074 PPP1R15A ---
ENSG00000108819 PPP1R9B -+o
ENSG00000167393 PPP2R3B o--a
ENSG00000068028 RASSF1 o--a
ENSG00000143878 RHOB +-o
ENSG00000020633 RUNX3 o--b
ENSG00000166949 SMAD3 NonAssociatedWithProgression
ENSG00000118046 STK11 o--a
ENSG00000154144 TBRG1 o--b
ENSG00000136270 TBRG4 o--a
ENSG00000105329 TGFB1 o--a
ENSG00000141510 TP53 o--a
ENSG00000143514 TP53BP2 oo-
ENSG00000152332 UHMK1 o--a
ENSG00000116809 ZBTB17 o--b