GeneSet KEGG_LYSINE_DEGRADATION (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -4.2 0.01271 26.0 11.0 3.59
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000157426 AASDH -+o
ENSG00000149313 AASDHPPT o+o
ENSG00000075239 ACAT1 NonAssociatedWithProgression
ENSG00000120437 ACAT2 o--b
ENSG00000137124 ALDH1B1 NonAssociatedWithProgression
ENSG00000072210 ALDH3A2 o--b
ENSG00000143149 ALDH9A1 o--b
ENSG00000116539 ASH1L o-o
ENSG00000119689 DLST o--a
ENSG00000104885 DOT1L o--b
ENSG00000127884 ECHS1 o--a
ENSG00000181090 EHMT1 NonAssociatedWithProgression
ENSG00000204371 EHMT2 o--b
ENSG00000105607 GCDH NonAssociatedWithProgression
ENSG00000138796 HADH --o
ENSG00000084754 HADHA NonAssociatedWithProgression
ENSG00000165671 NSD1 NonAssociatedWithProgression
ENSG00000105953 OGDH ---
ENSG00000083444 PLOD1 --o
ENSG00000106397 PLOD3 o--a
ENSG00000099381 SETD1A o--b
ENSG00000139718 SETD1B o--b
ENSG00000181555 SETD2 NonAssociatedWithProgression
ENSG00000145391 SETD7 o++a
ENSG00000183955 SETD8 o--b
ENSG00000143379 SETDB1 o--b
ENSG00000136169 SETDB2 o++b
ENSG00000170364 SETMAR NonAssociatedWithProgression
ENSG00000101945 SUV39H1 o--a
ENSG00000110066 SUV420H1 o+o
ENSG00000133247 SUV420H2 o--a
ENSG00000185973 TMLHE -oo
ENSG00000109685 WHSC1 o--b
ENSG00000147548 WHSC1L1 o--b