PEACHi
GeneSet HIV_human_PPI_GP120 (HIV_Collection.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -2.2 0.04176 32.0 25.0 18.9
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000179218 CALR ---
ENSG00000128595 CALU o--b
ENSG00000108349 CASC3 o-o
ENSG00000159259 CHAF1B o-o
ENSG00000153132 CLGN oo+
ENSG00000110367 DDX6 o--b
ENSG00000090520 DNAJB11 NonAssociatedWithProgression
ENSG00000102580 DNAJC3 NonAssociatedWithProgression
ENSG00000116406 EDEM3 o--a
ENSG00000196405 EVL NonAssociatedWithProgression
ENSG00000234545 FAM133B NonAssociatedWithProgression
ENSG00000172366 FAM195A --o
ENSG00000145907 G3BP1 ---
ENSG00000138757 G3BP2 NonAssociatedWithProgression
ENSG00000089597 GANAB o--a
ENSG00000130309 GLT25D1 o--a
ENSG00000197409 HIST1H3D +-o
ENSG00000206503 HLA-A +-o
ENSG00000166598 HSP90B1 NonAssociatedWithProgression
ENSG00000155304 HSPA13 o+o
ENSG00000173110 HSPA6 NonAssociatedWithProgression
ENSG00000120694 HSPH1 o+-
ENSG00000149428 HYOU1 o--b
ENSG00000115232 ITGA4 o--b
ENSG00000160255 ITGB2 o--a
ENSG00000161654 LSM12 o--b
ENSG00000102158 MAGT1 o-+
ENSG00000115275 MOGS o-o
ENSG00000065485 PDIA5 NonAssociatedWithProgression
ENSG00000105854 PON2 o++a
ENSG00000130175 PRKCSH o--b
ENSG00000142507 PSMB6 o-o
ENSG00000108671 PSMD11 NonAssociatedWithProgression
ENSG00000117906 RCN2 NonAssociatedWithProgression
ENSG00000070423 RNF126 o--a
ENSG00000132581 SDF2 NonAssociatedWithProgression
ENSG00000128228 SDF2L1 o--a
ENSG00000078808 SDF4 ---
ENSG00000058262 SEC61A1 ---
ENSG00000085415 SEH1L o-o
ENSG00000149257 SERPINH1 --o
ENSG00000129103 SUMF2 NonAssociatedWithProgression
ENSG00000055208 TAB2 o--b
ENSG00000170876 TMEM43 NonAssociatedWithProgression
ENSG00000136827 TOR1A NonAssociatedWithProgression
ENSG00000169905 TOR1AIP2 NonAssociatedWithProgression
ENSG00000239264 TXNDC5 o--b