PEACHi
GeneSet GTP hydrolysis and joining of the 60S ribosomal subunit (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -3.4 0.01001 69.0 20.0 9.8
o-o -2.4 0.035 69.0 12.0 5.79
DownRegulated -6.4 1.0E-5 69.0 59.0 40.75
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000173674 EIF1AX ---
ENSG00000134001 EIF2S1 o--a
ENSG00000125977 EIF2S2 NonAssociatedWithProgression
ENSG00000130741 EIF2S3 o--a
ENSG00000107581 EIF3A NonAssociatedWithProgression
ENSG00000106263 EIF3B o--a
ENSG00000184110 EIF3C o--b
ENSG00000100353 EIF3D o--a
ENSG00000104408 EIF3E +-o
ENSG00000130811 EIF3G ---
ENSG00000147677 EIF3H o+o
ENSG00000084623 EIF3I -o-
ENSG00000104131 EIF3J oo-
ENSG00000178982 EIF3K o+o
ENSG00000161960 EIF4A1 -o-
ENSG00000156976 EIF4A2 o+o
ENSG00000063046 EIF4B o--a
ENSG00000114867 EIF4G1 ---
ENSG00000106682 EIF4H NonAssociatedWithProgression
ENSG00000100664 EIF5 o--b
ENSG00000158417 EIF5B o--b
ENSG00000149806 FAU o-o
ENSG00000147403 RPL10 o-o
ENSG00000198755 RPL10A NonAssociatedWithProgression
ENSG00000142676 RPL11 o--b
ENSG00000197958 RPL12 NonAssociatedWithProgression
ENSG00000167526 RPL13 o--b
ENSG00000142541 RPL13A NonAssociatedWithProgression
ENSG00000188846 RPL14 o--a
ENSG00000174748 RPL15 o--a
ENSG00000215472 RPL17 o-o
ENSG00000105640 RPL18A o-o
ENSG00000108298 RPL19 o-o
ENSG00000122026 RPL21 o--a
ENSG00000116251 RPL22 +-o
ENSG00000125691 RPL23 NonAssociatedWithProgression
ENSG00000198242 RPL23A o--a
ENSG00000114391 RPL24 o--b
ENSG00000161970 RPL26 o-o
ENSG00000131469 RPL27 NonAssociatedWithProgression
ENSG00000166441 RPL27A o--a
ENSG00000108107 RPL28 o--b
ENSG00000162244 RPL29 o--a
ENSG00000100316 RPL3 -o-
ENSG00000156482 RPL30 o++b
ENSG00000071082 RPL31 o-+
ENSG00000144713 RPL32 NonAssociatedWithProgression
ENSG00000109475 RPL34 NonAssociatedWithProgression
ENSG00000136942 RPL35 o--b
ENSG00000182899 RPL35A NonAssociatedWithProgression
ENSG00000130255 RPL36 o-o
ENSG00000241343 RPL36A ---
ENSG00000145592 RPL37 NonAssociatedWithProgression
ENSG00000197756 RPL37A NonAssociatedWithProgression
ENSG00000198918 RPL39 o-+
ENSG00000174444 RPL4 o--b
ENSG00000122406 RPL5 NonAssociatedWithProgression
ENSG00000089009 RPL6 o--b
ENSG00000147604 RPL7 NonAssociatedWithProgression
ENSG00000148303 RPL7A -o-
ENSG00000161016 RPL8 ---
ENSG00000163682 RPL9 NonAssociatedWithProgression
ENSG00000089157 RPLP0 o--b
ENSG00000137818 RPLP1 NonAssociatedWithProgression
ENSG00000177600 RPLP2 NonAssociatedWithProgression
ENSG00000124614 RPS10 NonAssociatedWithProgression
ENSG00000142534 RPS11 o--a
ENSG00000112306 RPS12 o--a
ENSG00000110700 RPS13 NonAssociatedWithProgression
ENSG00000164587 RPS14 -o-
ENSG00000115268 RPS15 NonAssociatedWithProgression
ENSG00000134419 RPS15A o+-
ENSG00000105193 RPS16 o--b
ENSG00000231500 RPS18 o-o
ENSG00000105372 RPS19 -o-
ENSG00000140988 RPS2 o--a
ENSG00000008988 RPS20 o--a
ENSG00000186468 RPS23 o-o
ENSG00000138326 RPS24 NonAssociatedWithProgression
ENSG00000197728 RPS26 NonAssociatedWithProgression
ENSG00000177954 RPS27 o-o
ENSG00000143947 RPS27A o+o
ENSG00000233927 RPS28 o-o
ENSG00000213741 RPS29 NonAssociatedWithProgression
ENSG00000149273 RPS3 o--b
ENSG00000145425 RPS3A o-o
ENSG00000198034 RPS4X NonAssociatedWithProgression
ENSG00000129824 RPS4Y1 o--a
ENSG00000083845 RPS5 o--a
ENSG00000137154 RPS6 o--a
ENSG00000171863 RPS7 o--a
ENSG00000142937 RPS8 NonAssociatedWithProgression
ENSG00000170889 RPS9 o--b
ENSG00000168028 RPSA o--b
ENSG00000221983 UBA52 o--a