GeneSet G0 and Early G1 (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -3.6 0.00878 18.0 8.0 2.49
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000145386 CCNA2 o--b
ENSG00000105173 CCNE1 o--b
ENSG00000175305 CCNE2 NonAssociatedWithProgression
ENSG00000164045 CDC25A o--b
ENSG00000094804 CDC6 NonAssociatedWithProgression
ENSG00000170312 CDK1 o-+
ENSG00000123374 CDK2 oo-
ENSG00000157540 DYRK1A NonAssociatedWithProgression
ENSG00000101412 E2F1 o--b
ENSG00000205250 E2F4 ---
ENSG00000133740 E2F5 o--b
ENSG00000116478 HDAC1 ---
ENSG00000188223 LIN37 +o+
ENSG00000189308 LIN54 oo-
ENSG00000183814 LIN9 o+o
ENSG00000101057 MYBL2 o--b
ENSG00000132646 PCNA -o-
ENSG00000162521 RBBP4 NonAssociatedWithProgression
ENSG00000080839 RBL1 +o+
ENSG00000103479 RBL2 NonAssociatedWithProgression
ENSG00000198176 TFDP1 -o-
ENSG00000114126 TFDP2 o--b
ENSG00000131747 TOP2A o--b