GeneSet G-protein beta:gamma signalling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++b -2.2 0.04602 16.0 4.0 1.28
AllGenesAssociatedWithProgression -1.7976931348623157E308 0.0 16.0 16.0 11.66
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000078369 GNB1 o--a
ENSG00000172354 GNB2 ---
ENSG00000114450 GNB4 -+o
ENSG00000069966 GNB5 -o-
ENSG00000242616 GNG10 o++b
ENSG00000186469 GNG2 o++b
ENSG00000168243 GNG4 o--a
ENSG00000174021 GNG5 o+o
ENSG00000140992 PDPK1 -o-
ENSG00000105851 PIK3CG o++b
ENSG00000182621 PLCB1 -+o
ENSG00000137841 PLCB2 o-+
ENSG00000067560 RHOA o-o