PEACHi
GeneSet Deadenylation-dependent mRNA decay (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
DownRegulated -3.0 0.01562 34.0 28.0 20.08
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000158435 C2orf29 o--b
ENSG00000182973 CNOT10 ---
ENSG00000111596 CNOT2 o--b
ENSG00000088038 CNOT3 o--a
ENSG00000080802 CNOT4 ---
ENSG00000113300 CNOT6 +-o
ENSG00000138767 CNOT6L o--a
ENSG00000198791 CNOT7 --o
ENSG00000155508 CNOT8 oo-
ENSG00000162290 DCP1A o+o
ENSG00000151065 DCP1B o++b
ENSG00000172795 DCP2 o-o
ENSG00000110063 DCPS o--a
ENSG00000110367 DDX6 o--b
ENSG00000083520 DIS3 o--a
ENSG00000179151 EDC3 o-o
ENSG00000038358 EDC4 NonAssociatedWithProgression
ENSG00000161960 EIF4A1 -o-
ENSG00000156976 EIF4A2 o+o
ENSG00000141543 EIF4A3 NonAssociatedWithProgression
ENSG00000063046 EIF4B o--a
ENSG00000114867 EIF4G1 ---
ENSG00000171311 EXOSC1 NonAssociatedWithProgression
ENSG00000130713 EXOSC2 o--b
ENSG00000107371 EXOSC3 NonAssociatedWithProgression
ENSG00000178896 EXOSC4 --o
ENSG00000077348 EXOSC5 o--a
ENSG00000223496 EXOSC6 o--a
ENSG00000075914 EXOSC7 NonAssociatedWithProgression
ENSG00000123737 EXOSC9 o--b
ENSG00000175324 LSM1 o-o
ENSG00000204392 LSM2 --o
ENSG00000130520 LSM4 o--a
ENSG00000106355 LSM5 o++b
ENSG00000164167 LSM6 NonAssociatedWithProgression
ENSG00000130332 LSM7 o--a
ENSG00000070756 PABPC1 o--b
ENSG00000172239 PAIP1 o--b
ENSG00000135473 PAN2 NonAssociatedWithProgression
ENSG00000152520 PAN3 NonAssociatedWithProgression
ENSG00000140694 PARN o-o
ENSG00000166889 PATL1 NonAssociatedWithProgression
ENSG00000144580 RQCD1 NonAssociatedWithProgression
ENSG00000114127 XRN1 o++b